5,497 research outputs found

    Father Andrew Mullen 1790-1818: a study in early nineteenth century spirituality

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    This thesis is laid out in three parts: Part I. The life and death of Andrew Mullen. The life is based, to a large extent, on a long letter to his mother, Catherine Mullen, dated 7 January 1810. The letter gives a definite insight into his spirituality based on his membership of the Archconfraternity of the Blessed Sacrament. There is a hint that he had a premonition of an early death. Part II. The burial of Andrew Mullen and the immediate cult to him This is based on documentary evidence. Part III. Most of this part is a catalogue of testimonies taken from 1993 onwards. Then there is the conclusion on the popular devotion to Andrew Mullen stressing the theological aspect of the subject. In the course of writing the thesis it was decided to separate the documentary evidence from the oral tradition. This was advantageous in developing the thesis, and the documents provided a secure basis for the oral tradition. Two pieces of information were found in March 1997. They are death notices: 2 January 1819, The Leinster Journal and 7 January 1819, The Car low Morning Post. There is a slight discrepancy between the two on the date of his death. Also this discrepancy shows a slight difference from the date of the tombstone

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Trasmissible Spongiform Encephalopathies

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    Protein folding and misfolding, relevance to disease and function / Massimi Stefani -- Alzheimer's disease / Charlotte E. Teunissen and Tischa M. van der Cammen -- Improving Cholinergic Transmission -- Cholinergic transmission and acetylcholine release enhancers / Pierre Francotte, Pascal de Tullio and Bernard Pirotte -- AChE and its inhibition / Jure Stojan -- AChE inhibitors and their clinical assessment / Pierre Francotte, Pascal de Tullio and Bernard Pirotte -- Reduction in plaque formation / Christian Czech, Helmut Jacobsen and Celine Adessi -- Non-steroidal anti-inflammatory drugs (NSAIDs) / Bruno P. Imbimbo and Francesca Speroni -- 3-hydroxy-3-methyl-glutaryl-coenzyme reductase inhibitors / Dario Cattaneo -- A' polymerization reduction / Harry LeVine III and Corrine E. Augelli-Szafran -- Carbonic anhydrase activators as potential anti-Alzheimer's disease agents / Claudiu T. Supuran and Andrea Scozzafava -- Detection and reduction of neurofibrillary lesions / Jeff Kuret -- Protein misfolding in Alzheimer disease : pathogenic or protective? / Rudy J. Castellani ... [et al.] -- Enhancement of brain retinoic acid levels / Ann B. Goodman ... [et al.] -- Parkinson's disease : what is it? what causes it? and how can it be cured? / Tom Foltynie, Andrew W. Michell and Roger A. Barker -- Restoring dopamine levels / Nuno Palma .. [et al.] -- Huntington's disease / Claire-Anne Gutekunst and Fran Norflus -- Amyotrophic lateral sclerosis (motor neuron disease) / Teresa Sanelli ... [et al.] -- Transmissible spongiform encephalopathies (TSEs) / Michael D. Geschwind and Giuseppe Legname -- Overview / H. John Smith, Claire Simons and Robert D.E. Sewell

    Figure 3. A, B in Molecules, morphology, missing data and the phylogenetic position of a recently extinct madtom catfish (Actinopterygii: Ictaluridae)

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    Figure 3. A, B, pectoral girdle, ventral view, anterior at top. A, Noturus munitus, JFBM 43107; B, N. funebris, JFBM 43002. C–E, posttemporo-supracleithrum, posterior view, anterior into page. C, N. munitus, JFBM 43107; D, N. eleutherus, JFBM 43055; E, N. funebris, JFBM 43002. cl = cleithrum; pr = pectoral radial; ps = pectoral fin spine; sco = scapulo-coracoid. Numbers refer to characters and states listed in Appendix S2. Cartilage shown by grey shading. Scale bar = 1 mm.Published as part of Egge, Jacob J. D. & Simons, Andrew M., 2009, Molecules, morphology, missing data and the phylogenetic position of a recently extinct madtom catfish (Actinopterygii: Ictaluridae), pp. 60-75 in Zoological Journal of the Linnean Society 155 (1) on page 65, DOI: 10.1111/j.1096-3642.2008.00432.x, http://zenodo.org/record/544580

    Systematics of the combtooth blenny clade Omobranchus (Blenniidae: Omobranchini), with notes on early life history stages

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    Gibbs, Sean, Hundt, Peter J., Nelson, Andrea, Egan, Joshua P., Tongnunui, Prasert, Simons, Andrew M. (2018): Systematics of the combtooth blenny clade Omobranchus (Blenniidae: Omobranchini), with notes on early life history stages. Zootaxa 4369 (2): 270-280, DOI: 10.11646/zootaxa.4369.2.

    Aspects of supersymmetry in multiple membrane theories

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    PhDThis thesis consists of two parts. In the rst part we investigate the worldvolume supersymmetry algebra of multiple membrane theories. We begin with a description of M-theory branes and their intersections from the perspective of spacetime and worldvolume supersymmetry algebras. We then provide an overview of the recent work on multiple M2-branes focusing on the Bagger-Lambert theory and its relation to the Nambu-Poisson M5-brane and the ABJM theory. The worldvolume supersymmetry algebras of these theories are explicitly calculated and the charges interpreted in terms of spacetime intersections of M-branes. The second part of the thesis looks at l3 p corrections to the supersymmetry transformations of the Bagger-Lambert theory. We begin with a review of the dNS duality transformation which allows a gauge eld to be dualised to a scalar eld in 2+1 dimensions. Applying this duality to 02 terms of the non-abelian D2-brane theory gives rise to the l3 p corrections of the Lorentzian Bagger-Lambert theory. We then apply this duality transformation to the 02 corrections of the D2-brane supersymmetry transformations. For the `abelian' Bagger-Lambert theory we are able to uniquely determine the l3 p corrections to the supersymmetry transformations of the scalar and fermion elds. Generalising to the `non-abelian' Bagger-Lambert theory we are able to determine the l3 p correction to the supersymmetry transformation of the fermion eld. Along the way make a number of observations relating to the implementation of the dNS duality transformation at the level of supersymmetry transformations

    The Grouped Author-Topic Model for Unsupervised Entity Resolution

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    This paper describes a generative approach for tackling the problem of identity resolution in a completely unsupervised context with no fixed assumption regarding the true number of identities. The problem of entity resolution involves associating different references to authors (in a paper's author list, for example) with real underlying identities. The references may be written in differing forms or may have errors, and identical references may refer to different real identities. The approach taken here uses a generative model of both the abstract of a document and its list of authors to resolve identities in a corpus of documents. In the model, authors and topics are associated with latent groups. For each document, an abstract and an author list are generated conditioned on a given group. Results are presented on real-world datasets, and outperform the best performing unsupervised methods.</p

    The Simons Observatory: Astro2020 Decadal Project Whitepaper

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    International audienceThe Simons Observatory (SO) is a ground-based cosmic microwave background (CMB) experiment sited on Cerro Toco in the Atacama Desert in Chile that promises to provide breakthrough discoveries in fundamental physics, cosmology, and astrophysics. Supported by the Simons Foundation, the Heising-Simons Foundation, and with contributions from collaborating institutions, SO will see first light in 2021 and start a five year survey in 2022. SO has 287 collaborators from 12 countries and 53 institutions, including 85 students and 90 postdocs. The SO experiment in its currently funded form ('SO-Nominal') consists of three 0.4 m Small Aperture Telescopes (SATs) and one 6 m Large Aperture Telescope (LAT). Optimized for minimizing systematic errors in polarization measurements at large angular scales, the SATs will perform a deep, degree-scale survey of 10% of the sky to search for the signature of primordial gravitational waves. The LAT will survey 40% of the sky with arc-minute resolution. These observations will measure (or limit) the sum of neutrino masses, search for light relics, measure the early behavior of Dark Energy, and refine our understanding of the intergalactic medium, clusters and the role of feedback in galaxy formation. With up to ten times the sensitivity and five times the angular resolution of the Planck satellite, and roughly an order of magnitude increase in mapping speed over currently operating ("Stage 3") experiments, SO will measure the CMB temperature and polarization fluctuations to exquisite precision in six frequency bands from 27 to 280 GHz. SO will rapidly advance CMB science while informing the design of future observatories such as CMB-S4

    Temperature Dependence on Domain Switching Behavior in Lead Zirconate Titanate Under Electrical Load via In Situ Neutron Diffraction

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    The influence of temperature on the kinetics of domain switching in lead zirconate titanate was investigated by using in situ neutron diffraction. Samples were electrically loaded to 1 kV/mm at 30°C, 125°C, and 175°C, after which the diffracted patterns in the on- and off-state were compared. The results demonstrated that the degree of domain switching increases with increased temperature. Corroboration with hysteresis measurements showed that while the coercive field decreases withincreasing temperature, the degree of saturation increased significantly. According to Merz’s model, it is therefore apparent that, due to increased switching rate at high temperature, domain switchability increases with temperature
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