121,958 research outputs found
Formulación semiclásica de la aproximación adiabática hiperesférica de sistemas de dos electrones
No full textIP 1115-05-012-92No existe informe final1925-1937. -- Semiclassical calculations of intra-shell Sresonantes of doubly excited helium / P. V. Grujic,;Mahecha Gomez. -- En: Journal of Physics B: Atomic, Molecularand OpticalPhysics. -- Vol. 27 (1994); p.;S. Simonovic. -- En: Journal of Physics B: Atomic, Molecular andOptical Physics. -- Vol. 28 (1995); p.;1159-1171.;ARTICULO(S) EN REVISTA: Semiclassical hyperspherical matriz elements for helium doubly excited status / J
Shape transitions in excited states of two-electron quantum dots in a magnetic field
No full textWe use entanglement to study shape transitions in two-electron axially symmetric parabolic quantum dots in a perpendicular magnetic field. At a specific magnetic field value the dot attains a spherical symmetry. The transition from the axial to the spherical symmetry manifests itself as a drastic change of the entanglement of the lowest state with zero angular momentum projection. While the electrons in such a state are always localized in the plane (x-y) before the transition point, after this point they become localized in the vertical direction.Fil: Nazmitdinov, R.G.. Bogoliubov Laboratory Of Theoretical Physics, Joint Institute For Nuclear Research; Rusia. Universitat de Les Illes Balears; EspañaFil: Simonovic, N. S.. University of Belgrade; SerbiaFil: Plastino, Ángel Ricardo. Comisión de Regulación de Energía y Gas; Argentina. Universidad Nacional de La Plata; Argentina. Universidad de Granada; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; ArgentinaFil: Chizhov, A.V.. Bogoliubov Laboratory Of Theoretical Physics, Joint Institute For Nuclear Research; Rusi
Formulación semiclásica de la aproximación adiabática hiperesférica de sistemas de dos electrones
No full textIP 1115-05-012-92No existe informe final1925-1937. -- Semiclassical calculations of intra-shell Sresonantes of doubly excited helium / P. V. Grujic,;Mahecha Gomez. -- En: Journal of Physics B: Atomic, Molecularand OpticalPhysics. -- Vol. 27 (1994); p.;S. Simonovic. -- En: Journal of Physics B: Atomic, Molecular andOptical Physics. -- Vol. 28 (1995); p.;1159-1171.;ARTICULO(S) EN REVISTA: Semiclassical hyperspherical matriz elements for helium doubly excited status / J
Tribological behaviour of W-S-C coated ceramics in a vacuum environment
No full textSliding of the WSC coated ceramics (ball-on-disc configuration) was investigated under vacuum condition at multiple loads (2–18 N), and each experiment was followed by detailed Raman and SEM analysis of both the wear track and the wear scar (on the ball). Main finding is that under low loads (up to 8 N), wear is polishing, carbon structure becomes more ordered and the number of WS2 monolayer increases. Above 8 N, wear transitions into an abrasive regime interrupting the aforementioned processes increasing both friction and wear. Furthermore, roles of the coating components were differentiated: WS component is responsible for the low friction, whereas the carbon part is responsible for excellent wear properties.</p
Exercise elicits dynamic changes in extravascular lung water and haemodynamic congestion in heart failure patients with preserved ejection fraction
No full textA Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The vanishing author in computer-generated works: a critical analysis of recent Australian case law
No full textAbstract
The use of software is ubiquitous in the creation of many copyright works, yet the requirement in copyright law that every work have a human author who engages in independent intellectual effort means that its use may prevent copyright subsistence. Several recent Australian cases have refocused attention on authorship as an essential criterion of copyright subsistence, and these cases suggest that much computer-produced output may be authorless and thus lack copyright protection. This article, the first in a two-part series, analyses how each case deals with the question of authorship of computer-produced works and why the use of software diminishes copyright protection for a significant number of computer-generated works. The article critiques the application of conventional notions of human authorship developed in the pre-computer age to modern productions and suggests alternative approaches to authorship that satisfy both the major objectives of copyright policy and the need to adapt to the computer age. The article argues that, without a broader judicial approach to authorship of computer-generated works, Parliament must remedy the lacuna in protection for these ‘authorless’ works. Possible solutions for reform are suggested. In a forthcoming article, the author comprehensively examines those reform proposals
Diffusive author(s), cohesive author: Analysis of S/N (1994)
No full textThis study indicates the ways in which various aspects of the author(s) are brought forth in Dumb type’s performance art, the S/N production. Previous research has suggested a non-hierarchical organization of Dumb type and the absence of a “privileged author” in Dumb type’s collaborative work, S/N. However, the results that I have investigated from member’s interviews on the creative process of S/N along with my analysis of the recorded images of S/N, indicate a different aspect of the author(s). First, S/N was created through, so to speak, the collective ideas of the members of Dumb type. Further, S/N has at least nine quotations from previous performances, installations, and printed writings, besides the work-in-progress technique. Explicating one of the “author functions” as given by Michel Foucault, each text has plural subjects of the author. However, it has been revealed from members’ interviews that Teiji Furuhashi had a decision-making role in selecting the members’ ideas within the performance. Since then, S/N has had plural subjects of creation; however, Furuhashi is one of the subjects of creation along with the “privileged author.” S/N has plural authors (diffusive authors) yet at the same time, it has a “privileged author,” Teiji Furuhashi (cohesive author)
Synthesis and structure-activity relationship studies of marine-derived antimicrobial peptides and small cyclic peptidomimetics
No full textEffective antimicrobial drugs are the very core of modern medicine enabling successful prevention and treatment of infectious diseases. However, systemic misuse and overuse of antibiotics in human medicine, as well as in animal husbandry have led to widespread antibiotic-resistance, rendering many of these drugs ineffective. Therefore, there is an urgent need for new treatment options to conventional antibiotics.
Antimicrobial peptides, also known as host defense peptides, are one such option. These compounds are an important part of the innate immune system of different organisms and they are generally characterised by being short, structurally diverse, positively charged and amphipathic in nature. However, their toxicity to host cells, along with their often moderate antimicrobial activity, pose a major obstacle for their development as antibiotics. To effectively address this challenge, we need to better understand the structure-activity relationship of these compounds.
In the present work we investigated how different structural modifications affect antimicrobial and haemolytic properties of various marine-derived short antimicrobial peptides and cyclic peptidomimetics. We used three different peptide scaffolds: firstly, a 12-residue loop region of the marine antimicrobial peptide Turgencin A, secondly, a previously reported lead peptide (P6) derived from the heavy chain of the marine peptide EeCentrocin 1, and finally, a tetrapeptide scaffold containing non-canonical amino acid. We have shown that antimicrobial and haemolytic properties of Turgencin A and EeCentrocin 1 analogues can be fine-tuned by incorporating bulky, hydrophobic amino acids in the native sequence, by lysine to arginine substitution, and N-terminal acylation. For much smaller, tetrapeptide scaffold our study revealed that changes in amphipathicity and stereochemistry could be used to decrease the mammalian cell toxicity, while not significantly affecting potency of tetrapeptide analogues.
In summary, our findings show that structural modifications performed in the present work could serve as a viable strategy for the development of potent, non-haemolytic antimicrobial agents, that could help address the growing problem of antibiotic resistance
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