1,373 research outputs found
Richard M. Sheirich research collection : materials about Richard Beer-Hofmann 1866-2002
No full textThis collection consists of Richard M. Sheirich’s materials pertaining to his research on Richard Beer-Hofmann’s private correspondence and works. In addition to the original papers, correspondence, notes, and photos of Richard Beer-Hofmann and his family that Richard M. Sheirich gathered, the collection contains Sheirich’s correspondence with Richard Beer-Hofmann’s daughter Miriam Beer-Hofmann Lens, his and other scholars’ works on Beer-Hofmann, several photocopies of the original Beer-Hofmann papers, and Sheirich’s notes.Richard M. Sheirich's book, 'Der Briefwechsel mit Paula 1896-1937’ is available in the LBI Library.Richard M. Sheirich was born on October 9, 1927 in Erie, Pennsylvania. He studied German at Colgate University, Northwestern University and at Universität Hamburg, and earned a Ph. D. in German at Harvard University in 1965; his dissertation was titled “Die Historie von König David.”After teaching German at the University of California at Berkeley, Richard M. Sheirich became a faculty member at Pomona College in 1962 and retired from the same institution in 1996. Sheirich’s research interest was the Austrian literary movement Das Junge Wien and specifically Richard Beer-Hoffman’s work. He started working on Beer-Hofmann’s writings in the 1950s. His work in this field was the preparation of an inventory of the Richard Beer-Hofmann papers for Harvard University. As part of his research, Sheirich travelled to Vienna, Austria several times and conducted a long correspondence with Richard Beer-Hofmann’s daughter Miriam Beer-Hofmann Lens. Alongside other smaller publications, the result of Sheirich’s research was the publication of Der Briefwechsel mit Paula, 1896-1937, Richard Beer-Hofmann’s correspondence with his wife Paula.Richard M. Sheirich died at his home in Claremont on Dec. 11, 2011.Richard Beer-Hofmann was a Viennese author, poet, dramatist and theater director.Processeddigitize
DRfit: Java tool for analysis of discrete multi-well plate data
No full textDRfit is a Java tool for analysis of multiple data sets comprising replicates of discrete bivariate data. In particular, the software has been designed to allow convenient analysis of data structures obtained from multi-well plate assays.
When using this program, please cite:
Hofmann, A., Preston, S., Cross, M., Dilrukshi Herath, H.M.P., Simon, A., Gasser, R.B. (2019) DRfit: a Java tool for the analysis of discrete data from multi-well plate assays. BMC Bioinformatics 20, 262
Cum ... Simon Battierius, i.u.d. phil. pract. professor celeberr. promotor rite dictus Fridericum Battierium, ... Ioh. Rodolphum Beckhium, ... Ioh. Rodolphum Frey, ... Ioh. Rodolphum Wetstenium, ... primae laureae insignibus exornaret die X. Novemb. M DC LXXIV
No full texthaec faustae congratulationis ergo fudit I.I. Hofmann, g.l.p.Gelegenheitsschrift: HochschulwesenEnthält ein Gratulationsgedicht in lat. SpracheEinblattdruckGratulationsschrift phil. Basel, 167
Comparative Analysis of DFOS and Traditional Methods for Soil Settlement Monitoring in Civil Infrastructure
No full textAccurate estimation of soil settlements in the foundation layer and the structure itself are of paramount importance during and after the construction of a new earth embankment. Various methodologies are currently available for this aim; however, only a few of them provide precise information on the location and magnitude of deformation by measuring within the structure. Distributed Fiber Optic Sensing (DFOS), which is a relatively new structural health monitoring technique, has demonstrated considerable efficacy in the surveillance and early warning of structural performance. Its extensive application in geotechnical engineering is attributed to its capability for conducting continuous and precise measurements along the entire length of the fiber optic cable, making it particularly advantageous for large-scale projects characterized by material heterogeneity. This paper utilizes deformation-detecting fibers exploited with a Brillouin Optical Frequency Domain Reflectometry (BOFDR) to monitor the soil settlements induced by the construction of a new large embankment at Resia Lake (Northern Italy). The embankment, which spans 1.5 km in length and 100 m in base width, was constructed in two phases. Each phase involved a 10 m elevation of soil, primarily composed of sands, completed over two months with a one-year interval between the phases. During this interval, fluctuations in the lake's water level influenced the settlements of the structure. The implementation and evaluation of the innovative DFOS technique evidence that DFOSs are an alternative to traditional methods, such as long-base extensometers, as they provide distributed information over the monitored section permitting the identification of specific layers of significant deformation. This study reports and discusses the results obtained through DFOS and extensometers installed in a 30 m deep vertical borehole. Particular attention is given to the cost-benefit analysis of the methodologies employed, emphasizing the advantages and disadvantages of each tested monitoring technique
Re-Examination of Cyclized Products from Lycopodine and Clavolonine
No full textTitle: Re-Examination of Cyclized Products from Lycopodine and Clavolonine, Author: Norman M. C. You, Location: ThodeCyclized products derived from lycopodine and clavolonine through
the Hofmann and von Braun reactions were prepared and examined. From
evidence obtained new structures are proposed for the Hofmann products
of lycopodine and clavolonine.ThesisMaster of Science (MS
Enrollment to exams: Perceived stress dynamics among first-year physics students
No full textThe current dropout rate in physics studies in Germany is about 60%, with the majority of dropouts occurring in the first year. Consequently, the physics study entry phase poses a significant challenge for many students. Students’ stress perceptions can provide more profound insights into the processes and challenges during that period. In a panel study featuring 67 measuring points involving up to 128 participants at each point, we investigated students’ stress perceptions with the perceived stress questionnaire (PSQ), identified underlying sources of stress, and assessed self-estimated workloads across two different cohorts. This examination occurred almost every week during the first semester, and for one cohort also in the second semester, yielding a total of 3241 PSQ data points and 5823 stressors. The PSQ data indicate a consistent stress trajectory across all three groups studied that is characterized by significant dynamics between measuring points, spanning from M=20.1,SD=15.9 to M=63.6,SD=13.4 on a scale from 0 to 100. Stress levels rise in the first weeks of the lecture, followed by stable, elevated stress levels until the exams and a relaxation phase afterward during the lecture-free time and Christmas vacation. In the first half of the lecture period, students primarily indicated the weekly exercise sheets, the physics lab course, and math courses as stressors; later on, preparation for exams and the exams themselves emerged as the most important stressors. Together with the students’ self-estimated workloads that correlate with the PSQ scores, we can create a coherent picture of stress perceptions among first-year physics students, which builds the basis for supportive measures and interventions
Author response
No full textTranscription regulation in metazoans often involves promoter-proximal pausing of RNA polymerase (Pol) II, which requires the 4-subunit negative elongation factor (NELF). Here we discern the functional architecture of human NELF through X-ray crystallography, protein crosslinking, biochemical assays, and RNA crosslinking in cells. We identify a NELF core subcomplex formed by conserved regions in subunits NELF-A and NELF-C, and resolve its crystal structure. The NELF-AC subcomplex binds single-stranded nucleic acids in vitro, and NELF-C associates with RNA in vivo. A positively charged face of NELF-AC is involved in RNA binding, whereas the opposite face of the NELF-AC subcomplex binds NELF-B. NELF-B is predicted to form a HEAT repeat fold, also binds RNA in vivo, and anchors the subunit NELF-E, which is confirmed to bind RNA in vivo. These results reveal the three-dimensional architecture and three RNA-binding faces of NELF
Making continental crust through slab melting: Constraints from niobium-tantalum fractionation in UHP metamorphic rutile
No full textThe formation of the continental crust (CC) is one of the most important processes in the evolution of the silicate Earth. Exactly how the CC formed is the subject of ongoing debate that focuses on its subchondritic Nb/Ta ratio. Nb and Ta are "geochemical identical twins," so they usually do not fractionate from each other. Here, we show that rutile grains from hydrous rutile-bearing eclogitic layers recovered from drillcores in the Dabie-Sulu ultrahigh pressure terrain have highly variable Nb/Ta values (ranging from 5.4 to 29.1, with an average of 9.8 +/- 0.6), indicating major fractionation of Nb and Ta most likely occurred during blueschist to amphibole-eclogite transformation in the absence of rutile. It is suggested that the released fluids with subchondritic Nb/Ta were transported to, and retained by, hydrous rutile-bearing eclogite in colder regions, resulting in suprachondritic Nb/Ta ratios for drier eclogite in hotter regions. Further dehydration of hydrous rutile-bearing eclogites cannot transfer the fractionated Nb/Ta values to the CC due to the low solubility of Nb and Ta in fluids in the presence of rutile, while dehydration-melting results in a major component of the CC, the tonalite-trondhjemite-granodiorite (TTG) component, which is responsible for the low Nb/Ta of the CC. Consequently, residual eclogites have variable but overall suprachondritic Nb/Ta. (c) 2006 Elsevier Inc. All rights reserved
Single Crystal X-Ray Diffraction Study of Pressure and Temperature Induced Spin Trapping in a Bistable FeII Hofmann Framework
No full textHigh-pressure single crystal X-ray diffraction has been used to trap both the low-spin (LS) and high-spin (HS) states of the iron(II) Hofmann spin crossover framework, [FeII(pdm)(H2O) [Ag(CN)2]2·H2O, under identical experimental conditions, allowing the structural changes arising from the spin-transition to be deconvoluted from previously reported thermal effects
Als Der Wohl-Edle, Großachtbare und Wohlgelahrte Herr Gottfried Hoffmann, Von Lommatsch aus Meissen, Auf der Weltberühmten Vniuersitaet Leipzig Anno 1725. den 15. Febr. die längst-verdiente Magister-Würde rühmlichst erhielte, Wollte seinen Glückwunsch nebst kürtzlicher Vorstellung Von dem berühmten Simon Stein, und andern gelehrten Lommatschern wohlmeinend ablegen M. George Samuel Hermann, Mitvv. Misn. Med. C.
No full textVorlageform des Erscheinungsvermerks: Leipzig, druckts Johann Gottlieb Bauch
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