11,994 research outputs found
TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation
The interaction between TACC3 (transforming acidic coiled coil protein 3) and the microtubule polymerase ch-TOG (colonic, hepatic tumor overexpressed gene) is evolutionarily conserved. Loading of TACC3–ch-TOG onto spindle microtubules requires the phosphorylation of TACC3 by Aurora-A kinase and the subsequent interaction of TACC3 with clathrin to form a microtubule binding surface. Whether there is a pool of TACC3–ch-TOG that is independent of clathrin in human cells, and what is the function of this pool, are open questions. Here, we report that TACC3 is recruited to the plus-ends of microtubules by its association with ch-TOG and that this pool is independent of phosphorylation and binding to clathrin. The plus-end binding of TACC3–ch-TOG persists in interphase and we propose that one cellular function of TACC3–ch-TOG is to modulate cell migration. We also describe the distinct subcellular pools of TACC3, ch-TOG and clathrin. TACC3 is often described as a centrosomal protein, but we show that there is no significant population of TACC3 at centrosomes. The delineation of distinct protein pools reveals a simplified view of how these proteins are organized and controlled by post-translational modification
Pseudoradial spaces: finite products and an example from CH
∗ The first named author’s research was partially supported by GAUK grant no. 350,
partially by the Italian CNR. Both supports are gratefully acknowledged. The second author
was supported by funds of Italian Ministery of University and by funds of the University of
Trieste (40% and 60%).Aiming to solve some open problems concerning pseudoradial
spaces, we shall present the following: Assuming CH, there are two
semiradial spaces without semi-radial product. A new property of pseudoradial
spaces insuring the pseudoradiality of a product is presented
Ch. Wackenheim, Quand Dieu se tait, Coll. Théologies, 2002
Knaebel Simon. Ch. Wackenheim, Quand Dieu se tait, Coll. Théologies, 2002. In: Revue des Sciences Religieuses, tome 77, fascicule 1, 2003. pp. 113-114
Ch. Wackenheim, Quand Dieu se tait, Coll. Théologies, 2002
Knaebel Simon. Ch. Wackenheim, Quand Dieu se tait, Coll. Théologies, 2002. In: Revue des Sciences Religieuses, tome 77, fascicule 1, 2003. pp. 113-114
Ch. Wackenheim, Entre la routine et la magie, la messe, 1982
Knaebel Simon. Ch. Wackenheim, Entre la routine et la magie, la messe, 1982. In: Revue des Sciences Religieuses, tome 57, fascicule 2, 1983. pp. 164-165
Un fragment du commentaire de Joseph Kimhi sur Job (ch. I et XXXIV, 17, à XLII)
Eppenstein Simon. Un fragment du commentaire de Joseph Kimhi sur Job (ch. I et XXXIV, 17, à XLII). In: Revue des études juives, tome 37, n°73, juillet-septembre 1898. pp. 86-102
Jacques Simon, Carolles, Manche, Ed. Ch. Corlet, Réédition 1990 du volume de 1949
Boullard Bernard. Jacques Simon, Carolles, Manche, Ed. Ch. Corlet, Réédition 1990 du volume de 1949. In: Études Normandes, 39e année, n°4, 1990. Prospective et aménagement - une société en mouvement. p. 96
Fernand Chapouthier et Louis Méridier, Euripide. Oreste. Texte établi et annoté par F. Ch. et traduit par L. M
Bouquiaux-Simon Odette. Fernand Chapouthier et Louis Méridier, Euripide. Oreste. Texte établi et annoté par F. Ch. et traduit par L. M. In: L'antiquité classique, Tome 30, fasc. 2, 1961. pp. 555-558
East African pholcid spiders: an overview, with descriptions of eight new species (Araneae, Pholcidae)
This paper summarizes current knowledge about East African pholcids. East Africa is defined as the area from 12°S to 5°N and from 28° to 42°E, including all of Uganda, Kenya, Burundi, Rwanda, and Tanzania. An annotated list of the 15 genera and 87 species recorded from this area is given, together with distribution maps and an identification key to genera. Most East African species (90%) belong to one of only six genera: Buitinga Huber, 2003 (21 species); Smeringopus Simon, 1890 (18); Pholcus Walckenaer, 1805 (17); Spermophora Hentz, 1841 (12); Leptopholcus Simon, 1893 (5) and Quamtana Huber, 2003 (4). Eight species for which DNA sequence data have been published recently are newly described: Buitinga batwa sp. nov., B. wataita sp. nov., Spermophora mau sp. nov., S. maathaiae sp. nov., S. bukusu sp. nov., S. kirinyaga sp. nov., S. kyambura sp. nov. and Quamtana nyahururu sp. nov. Crossopriza johncloudsleyi Deeleman-Reinhold & van Harten, 2001, previously only known from Yemen, is redescribed based on specimens from Kenya. Additional new records are given for 21 previously described species
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