50,067 research outputs found
Jurisprudence – Theories of private law
No full textNote drawing attention to the upsurge in interest, amongst British and American legal scholars, in the construction of general theories of private law. The author looks at the common law structure, notions of why theories arise, law and economics and ideas of corrective justice. Piece by Dr N. E. Simmonds (Reader in Jurisprudence, Fellow of Corpus Christi College, University of Cambridge) published in Amicus Curiae - Journal of the Institute of Advanced Legal Studies and its Society for Advanced Legal Studies. The Journal is produced by the Society for Advanced Legal Studies at the Institute of Advanced Legal Studies, University of London
Jurisprudence – Theories of private law
No full textNote drawing attention to the upsurge in interest, amongst British and American legal scholars, in the construction of general theories of private law. The author looks at the common law structure, notions of why theories arise, law and economics and ideas of corrective justice. Piece by Dr N. E. Simmonds (Reader in Jurisprudence, Fellow of Corpus Christi College, University of Cambridge) published in Amicus Curiae - Journal of the Institute of Advanced Legal Studies and its Society for Advanced Legal Studies. The Journal is produced by the Society for Advanced Legal Studies at the Institute of Advanced Legal Studies, University of London
Herpes simplex encephalitis as a complication of adjuvant chemotherapy treatment for breast cancer
No full textRecommended from our members
Law as a moral idea /
No full textNigel Simmonds provides an original critique of legal positivism, arguing that the institutions of law, and the structures of legal thought, can only be understood by reference to a moral ideal - an ideal of freedom, or independence from the power of others
The synthesis of monodisperse alkanes with long chains
No full textThis thesis discusses reasons for the interest in monodisperse long chain alkanes and describes attempts, past and present, to synthesise such molecules. Chapter 1 discusses why the synthesis of such molecules are important and the objectives of this project. Chapter 2 reviews the methods previous groups have devised to prepare pure samples of long chain alkanes. In particular, work carried out by Whiting et al. at Bristol, whose scheme formed the basis of the early work in Durham. Chapter 3 describes the work in Durham and improvements which were made to Whiting's method, allowing the synthesis of longer chain lengths and greater quantities of materials to be achieved. Chapter 4 provides a summary of the practical work carried out by the author. Chapter 5 gives experimental details of the work described in Chapter 4
The differential influence of pain and fatigue on physical performance and health status in ambulatory patients with human immunodeficiency virus
No full textObjectives: The purposes of this study were to: 1) characterize physical performance in individuals with human immunodeficiency virus; and 2) examine group differences by pain and fatigue on a multivariate profile of disease, physical, and psychologic symptoms.Methods: One hundred outpatients, 78 men and 22 women (mean age 40.70 +/- 7.49 years) participated. Patients completed a battery of physical performance tests in which the time taken or the distance reached or walked was measured. Self-report questionnaires included measures of pain (0-10 numerical rating scale), fatigue (Brief Fatigue Inventory), and perceived health status (Medical Outcomes Survey-HIV scale).Results: Physical performance was compromised in a task specific manner. Patients took twice as long as healthy individuals on a belt-tie and 4 times as long on a sit-to-stand task and in 6 minutes walked 75% of the distance covered by healthy individuals. Fifty percent of patients (n = 50) had pain at the time of testing (mean 6.3 +/- 2.4), and 98% had fatigue (mean 5.4 +/- 2.3). Multivariate analysis of variance showed pain had a greater influence on performance than fatigue. Pain, distance walked in 6 minutes, and unloaded forward reach accounted for 26% of the variability in quality of life (r = 0.51, P <= 0.0001).Discussion: Pain has a substantial impact on physical performance and quality of life among ambulatory human immunodeficiency virus patients. Fatigue also impacts physical performance. Compromised ability to perform certain physical tasks affects quality of life. Further investigation of the roles of these relevant variables should be investigated in path analyses
Structural and solvatochromic studies of a series of tricyanoquinodimethane-based zwitterions
No full textThe synthesis and characterization of three new solvatochromic tricyanoquinodimethane zwitterionic systems is reported. (Z)-{?-[N-(1-Propyl)benzothiazolium-2-yl]-alpha-cyano-4-styryl}dicyanomethanide, C3H7(2)BT3CNQ, (Z)-{?-[ N-(1-propyl)benzothiazolium-2-yl]-alpha-cyano-4-(2,3,5,6-tetrafluorostyr yl)}dicyanomethanide, C3H7(2)BT3CNQF(4), and (Z)-{?-[N-(1-butyl)benzoselenazolium-2-yl]-alpha-cyano-4-styryl}dicya nomethanide, C4H9(2)BS3CNQ, exhibit negative solvatochromism, consistent with a transition from an ionic ground state to a significantly less polar excited state. X-Ray crystallography measurements confirm the zwitterionic ground state of these novel T3CNQ-based chromophores. The solvatochromic properties of these compounds are compared to those of a series of related quinolinium/pyridinium adducts, and also with those of the Reichardt betaine dye
Supplement_1_-_Member_Company_Survey - Accelerating Adoption of Patient-Facing Technologies in Clinical Trials: A Pharmaceutical Industry Perspective on Opportunities and Challenges
No full textSupplement_1_-_Member_Company_Survey for Accelerating Adoption of Patient-Facing Technologies in Clinical Trials: A Pharmaceutical Industry Perspective on Opportunities and Challenges by Ashley M. Polhemus, Hassan Kadhim, Shelly Barnes, Susan E. Zebrowski, Alex Simmonds, Shirley N. Masand, Jaclyn Banner, and Melissa Dupont in Therapeutic Innovation & Regulatory Science</p
Supplement_4_-_Patient_Advisory_Board_Interview_Guide - Accelerating Adoption of Patient-Facing Technologies in Clinical Trials: A Pharmaceutical Industry Perspective on Opportunities and Challenges
No full textSupplement_4_-_Patient_Advisory_Board_Interview_Guide for Accelerating Adoption of Patient-Facing Technologies in Clinical Trials: A Pharmaceutical Industry Perspective on Opportunities and Challenges by Ashley M. Polhemus, Hassan Kadhim, Shelly Barnes, Susan E. Zebrowski, Alex Simmonds, Shirley N. Masand, Jaclyn Banner, and Melissa Dupont in Therapeutic Innovation & Regulatory Science</p
Supplement_2_-_Member_Company_Interview_Guide - Accelerating Adoption of Patient-Facing Technologies in Clinical Trials: A Pharmaceutical Industry Perspective on Opportunities and Challenges
No full textSupplement_2_-_Member_Company_Interview_Guide for Accelerating Adoption of Patient-Facing Technologies in Clinical Trials: A Pharmaceutical Industry Perspective on Opportunities and Challenges by Ashley M. Polhemus, Hassan Kadhim, Shelly Barnes, Susan E. Zebrowski, Alex Simmonds, Shirley N. Masand, Jaclyn Banner, and Melissa Dupont in Therapeutic Innovation & Regulatory Science</p
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