1,720,985 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Vascular Growth in the Fetal Lung
Get PDFThe structure of the lung is truly remarkable. It is primarily composed of three branched tubular networks (the airway, pulmonary artery and vein, bronchial artery and vein) which supply blood and air to the site of gas exchange and which maintain nutrient supply to supporting tissues. This complex interwoven network is packed into a chest cavity with a volume of 6 litres but yet it services a gas-exchange surface area of 130m2, the floor area of a comfortably sized Mediterranean holiday villa! Weibel (1991) tells us that if this surface area were arranged as a balloon it would possess a radius of 3m and a volume of 113,000 litres, more than 18 thousand times the space available in the chest cavity. The process which drives this exceptional packaging involves repeated cycles of ordered branching to create a fractal network of tubules whose core dimensions decrease at a precise and regular rate with each successive branch. This is a high “gain-of–structure” process. In the airway, 23 generations of branching form a conducting tubular network with 17 million branches and a combined length of more than 7km. This provides convective air flow to 480 million alveoli each of which are located along a path length that is no further than 45cm from the external atmosphere. The pulmonary vasculature forms along side the airway but undergoes an additional five generations of branching to form the capillary network that surrounds each alveolus. If you simply assumed that each alveolus (diameter ~200?m) was serviced by only one blood vessel you would calculate that the alveolar capillary bed alone runs to nearly 100 km in length. Realistic attempts at modelling this structure in three dimensions suggest that it is, in all probability, between 2 and 6 thousand km long (Muhlfield et al., 2010), illustrating the impressive capacity of fractal branching processes to package colossal structures into ever smaller spaces.</p
Supplementary_figure_1 – Supplemental material for Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis
No full textSupplemental material, Supplementary_figure_1 for Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis by Monica Madalina Tucureanu, Alexandru Filippi, Nicoleta Alexandru, Cristina Ana Constantinescu, Letitia Ciortan, Razvan Macarie, Mihaela Vadana, Geanina Voicu, Sabina Frunza, Dan Nistor, Agneta Simionescu, Dan Teodor Simionescu, Adriana Georgescu and Ileana Manduteanu in Diabetes & Vascular Disease Researc
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Vascular Repair and Remodeling: A Review
Get PDFCardiovascular diseases (CVDs) such as ischemic heart disease (IHD), stroke, and peripheral artery disease (PAS) are the leading cause of mortality and morbidity around the world: about 30% of global deaths and 10% of global disease burden a year are due to CVDs.In this chapter, we will analyze the classic concepts of vascular remodeling, to later expand the concepts and physiopathological mechanisms of vascular inflammation. The role of immunomodulation from IL-6R alpha and the JAK / STAT3 intracellular cascade, as an activator of vascular remodeling mechanisms. In addition, the role of new drugs such as LCZ696 and immunomodulators involved in the local inflammatory response will also be analyzed.The concept of remodeling and vascular inflammation, which a decade ago was only important at the level of basic research, step by step has proved crucial in the appearance of atherosclerosis, called subclinical atherosclerosis. Much progress has been made in the treatment and discovery of pathophysiological mechanisms, rest improve the studies of deterrence and its correlation with the reduction of cardiovascular risk, this is perhaps, the decade in which we can advance in this.Fil: Renna, Nicolas Federico. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFil: García, Rodrigo Damián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; ArgentinaFil: Ramírez, Jésica. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; ArgentinaFil: Miatello, Roberto Miguel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mendoza. Instituto de Medicina y Biología Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias Médicas; Argentin
Physiologic and Pathologic Angiogenesis
No full textThe purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all
Supplementary_Table_1 – Supplemental material for Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis
No full textSupplemental material, Supplementary_Table_1 for Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis by Monica Madalina Tucureanu, Alexandru Filippi, Nicoleta Alexandru, Cristina Ana Constantinescu, Letitia Ciortan, Razvan Macarie, Mihaela Vadana, Geanina Voicu, Sabina Frunza, Dan Nistor, Agneta Simionescu, Dan Teodor Simionescu, Adriana Georgescu and Ileana Manduteanu in Diabetes & Vascular Disease Researc
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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