1,720,958 research outputs found
Ruolo dello specialista ORL nella valutazione degli stadi preclinici della malattia di Alzheimer
No full textCon la standardizzazione dei test olfattometrici lo specialista otorinolaringoiatra viene ad assumere un ruolo determinante nella diagnosi delle malattie neurodegenerative ed in particolare negli stadi preclinici della malattia di Alzheimer (AD). Sulla base di queste nuove acquisizioni si propone che la valutazione otorinolaringoiatrica e la somministrazione del test olfattometrico da parte dello specialista venga introdotta nella batteria di test diagnostici per gli stadi preclinici dell’AD. In questo lavoro evidenziamo il ruolo dello Sniffin’ Sticks Screening Test (SSST) nella valutazione del paziente affetto da malattie neurodegenerative anche alla luce dei risultati ottenuti nelle predemenze ed in particolare nei pazienti con amnesic Mild Cognitive Impairment (aMCI)
La clinica delle disgeusie.Argomenti di otorinolaringoiatria moderna Anno IV Supplemento n°5 Ottobre 2004, pp. 14-16
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
smell and preclinical Alzheimer disease: study of 29 patients with amnesic mild cognitive impairment
No full textObjectives: To evaluate the olfactory function in patients with amnesic mild cognitive impairment (aMCI) and the relationship to
the progression from aMCI to Alzheimer disease (AD.
Design: Cohort prospective study on aMCI patients at the first evaluation (T0) and at the 18-month follow-up (T1.
Setting: Alzheimer Unit of the University of L’Aquila, Italy.
Methods: Twenty-nine aMCI patients were enrolled in this study.
Main Outcome Measures: Olfactory function was studied with the Sniffin’ Sticks Screening Test (SSST) and the Sniffin’ Sticks
Extended Test (SSET). Olfactory functions were related to neurocognitive functions assessed by the Mini-Mental State Examination
(MMSE) and the Mental Deterioration Battery (MDB.
Results: At T0, aMCI patients showed an olfactory impairment and all of the aMCI patients had lower olfaction scores at T1. At
T1, 9 of the 29 aMCI patients (31%) developed AD and had lower mean SSST and SSET scores than 20 aMCI patients who did not develop AD. The most significant relationship was found between olfactory discrimination and visuospatial ability, language skill,
and the Rey Immediate test of the MDB and between olfactory identification and the Rey Delayed test.
Conclusion: Odour discrimination and identification performance correlated more prominently than detection thresholds with
performance on neuropsychological tests. We concluded that the olfactory deficit occurs early in aMCI, so we suggest introducing
the clinical routine use of the olfactory test for early identification of the progression of the decline from aMCI to AD
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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