117,401 research outputs found
In vitro response of macrophages and lymphocytes of pigs fed with aflatoxins B1 and G1.
No full textEUROPEAN JOURNAL OF VETERINARY PATHOLOG
Author Correction: Female mouse tears contain an anti-aggression pheromone (Scientific Reports, (2020), 10, 1, (2510), 10.1038/s41598-020-59293-9)
No full textThe Supplementary Information published with this Article contains errors. The footage contained in Supplementary Video S2 is a duplicate of Supplementary Video S1, which shows “Intermale aggression test: intruder mouse swabbed with water” rather than “Intermale aggression test: intruder mouse swabbed with male tears”. The correct Supplementary Video S2 file is linked to this correction notice
The vomeronasal receptor V2R2 does not require escort molecules for expression in heterologous systems
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Distribution of c-fos in the accessory olfactory bulb of prepubertal female mice exposed to pheromonal cues
No full textFemale mouse tears contain an anti-aggression pheromone
No full textTears contain pheromones that trigger specific behavioral responses. In the mouse, male tear fluid is involved in long and short-term effects such as the receptive behavior and pregnancy block in females and the aggression in males. In contrast, pup tears exert an inhibitory effect on male mating behavior, also promoting sexual rejection in females. In the rat, a male lacrimal protein acts as an intraspecific and heterospecific signal enhancing sexual behavior in females and evoking avoidance behavior in mouse. However, behavioral effects of female tears on male behavior have yet to be described. Here, we report that female lacrimal fluid of different mouse strains contains a relatively small and involatile factor that abolishes inter-male aggression switching it into a copulatory behavior. The production of this molecule by the lacrimal glands is not affected by the estrous cycle but it is sensitive to ovariectomy, thus suggesting a control mediated by hormones. Moreover, this lacrimal anti-aggression pheromone modulates the activity of the lateral habenula, a brain area responsible for the valence of the aggressive interactions
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