112 research outputs found
Dynamic behaviour restructuring mediates dopamine-dependent credit assignment
No full textFunding Information: We thank V. Athalye for feedback; A. Vaz and C. Carvalho for mouse colony management; the members of the Costa laboratory for comments; the members of the Scientific Hardware Platform, Histopathology Platform, Scientific Software Platform and Advanced Bioimaging & BioOptics Experimental Platform (member of the Portuguese Platform of Bioimaging (PPBI-POCI-01-0145-FEDER-022122) of the Champalimaud Institute for help; S. Mutlu, D. Bento, P. Carriço., P. Silva and J. Araujo for hardware/software assistance; I. Marcelo for assistance with multinomial logistic regression; N. Loureiro for assistance with inertial sensor calculations; M. Mendoça, C. Alcacer, H. Rodrigues and D. Peterka for help with experimental set-ups; the members of the M. Carey laboratory for sharing apparatus; S. Fusi for project feedback; and R. Junker for advice on dynamic range boxes. This work was supported by Life Sciences Research Fellowship and NINDS K99/R00 Award (1K99NS112575) granted to J.C.Y.T. and National Institute of Health funding (5U19NS104649) and the Aligning Science Across Parkinson’s (ASAP-020551) through the Michael J. Fox Foundation for Parkinson’s Research (MJFF) to R.M.C. The authors have applied a CC BY NC public copyright license for the manuscript. Publisher Copyright: © The Author(s) 2023.Initial dopamine self-stimulations reinforced not only the stimulation-producing target action, but also actions similar to the target action and actions that occurred a few seconds before stimulation, and repeated pairings led to a gradual refinement of the behavioural repertoire to home in on the target actions.publishersversionpublishe
Accumulation Of Elements In Annual Tree Rings Measured By Synchrotron X-ray Fluorescence Analysis
No full textWood samples of hardwood (Eucalyptus sp.) and softwood (Pinus sp.) showing typical anatomical features treated with CCA (copper-chromium-arsenic) were analyzed. The distribution and quantification of metals in the sapwood/ heartwood (Eucalyptus sp.) and in the growth-rings (Pinus sp.) were obtained. The samples were scanned in 320 μm steps in the vertical direction. An x-ray beam of ∼320 × 180 urn was used. For excitation of the elements white beam synchrotron radiation was employed and for x-ray detection an Si(Li) semiconductor detector. The x-ray fluorescence intensities for the elements K, Ca, Cr, Mn, Cu, Zn and As were measured. Heterogeneous distribution of the elements was verified across growth-rings indicating irregular efficiency of the preservative distribution inside wood in the softwood samples. As expected, in eucalyptus the presence of the elements Cr, Cu and As was verified in the sapwood region only. Copyright © 2005 John Wiley & Sons, Ltd.345411416Martin, R.R., Shan, T.K., Wong Won, G., Jones, K.W., Feng, H., (2001) X-ray Spectrom., 30, p. 338Matsunaga, H., Matsumura, J., (2004) ODAK. IAWA J., 25, p. 79Daniel, G.F., Nilsoon, T., (1988) 19th Annual Meeting: The International Research Group on Wood Preservation, p. 17. , Anals. Madrid: IRG/WPLepage, E.S., (1986) Manual de Preservação de Madeiras, 2, p. 523. , Instituto de Pesquisas Tecnológicas do Estado de São Paulo: São PauloSánches, H.J., Pérez, C.A., Grenón, M., (2000) Nucl. Instrum. Methods B, 170, p. 211Bernasconi, G., Tajani, A., (1996) Quantitative X-ray Analysis System (QXAS) Software, Package: Documentation Version 1.2, , International Atomic Energy Agency: ViennaSilva, R.M.C., (2002), Doctoral Thesis, CENA/USP, PiracicabaSalvador, M.J., Dias, D.A., Moreira, S., Zucchi, O.L.A.D., (2000) J. Trace Microprobe Technol., 21, p. 377Taiz, L., Zeiger, E., (2002) Plant Physiology, , Sinauer Associates Inc. Publishers, Sunderland, MA, USAHenshaw, B., (1979) Int. Biodeterior. Bull., 15, p. 66Helmisaari, H.S., Sitala, T., (1989) Scand. J. For. Res., 4, p. 443Larsson, C., Helmisaari, H.S., (1998) X-ray Spectrom., 27, p. 133Punshon, T., Bertsch, P.M., Lanzirotti, A., Mcleod, K., Burger, J., (2003) Environ. Sci. Technol., 37, p. 1766Harju, L., Lill, J.O., Saarela, K.E., Heselius, S.J., Hernberg, F.J., Lindross, A., (1996) Nucl. Instrum. Methods Phys. Res. B, 109-110, p. 536Thompson, R., (1991) The Chemistry of Wood Preservation, , Royal Society of Chemistry: CambridgePanshin, A.J., Zeeuw, C., (1964) Textbook of Wood Technology, 1. , McGraw-Hill: New YorkKoch, P., (1972) Utilization of the Southern Pines, , USDA: Washington, DCHillis, W.E., Brown, A.G., (1978) Eucalyptus for Wood Production, , CSIRO Australia: MelbourneTomazello Filho, M., (1984) IAWA Bull., 5, p. 347Ferreira, C.A., Bellote, A.F.J., Silva, H.D., (1993) 7° Congresso Florestal Brasileiro e 1° Congresso Florestal Panamericano, p. 227. , Anais. São Paulo SBS/SBEFHunt, G.M., Garrayy, G.A., (1953) Wood Preservation, , McGraw-Hill: New Yor
Flexibiliteit in het ontwikkelingsproces: Stationsgebieden
No full textIn the coming decades, the attention paid to urban area development will increasingly be focused on suburban area locations. These inner city redevelopments are increasingly made up of property development and infrastructure development. The enormous size of these projects makes this form of development extra complex. Because of the large scope of the projects and the increasing number of actors that is participating in these projects, this will result in a longer development process. If one takes a closer look at these projects, one can see that the projects are often cumbersome and difficult adaptable to changes in the process environment. The tight schedules often used in current and past processes, that describe the process from start to finish, will no longer be able function adequately. Holding on to a fixed image in the future, can mean that the property program will not match the future demand on the moment of delivery. Is flexibility the key to succes?Urban Area DevelopmentReal Estate and HousingArchitectur
Towards a New Model for Collaboration: Evaluation of the effectiveness and efficiency of the “Aronsohn contracting vision”
No full textThe research in this thesis is about the Aronsohn contracting vision, an innovative contract form developed by Aronsohn management. After successfully applying the method on a number of projects they were interested in a more formal evaluation of the method. This evaluation is presented in this report. The idea of Aronsohn is compared to the traditional contract, the bouwteam contract, the D&C contract and later also the Design Novate Construct (DNC) contract.Construction Management and EngineeringBouwCivil Engineering and Geoscience
Gravitational signature of titan's (sub) surface lakes: Discovering the composition of the lakes using a MEMS micro gradiometer mounted on a balloon
No full textAerospace Engineerin
Postingestive Modulation of Food Seeking Depends on Vagus-Mediated Dopamine Neuron Activity (Neuron (2020) 106(5) (778–788.e6), (S0896627320302166), (10.1016/j.neuron.2020.03.009))
No full textFunding Information: This work was supported by Fundação para a Ciência e Tecnologia ( FCT ) through a postdoctoral fellowship ( SFRH/BPD/880972/2012 to A.B.F.) and grant LISBOA-01-0145-FEDER-030845 , co-funded by FEDER under the Lisboa2020 Partnership Agreement and by national funds through FCT (to A.B.F., R.M.C., J.A.d.S., and A.J.O.-M.); by a doctoral fellowship from the Gulbenkian Foundation (to J.A.d.S.); by the Intramural Research Program of the NIMH ( ZIA-MH002497-29 to C.R.G.); by ERA-NET, ERC ( COG 617142 ), and HHMI ( IEC 55007415 ) (to R.M.C.); and by the BIAL Foundation ( 176/10 ) and the AXA Research Fund (to A.J.O.-M.). Further support was obtained from the research infrastructure Congento, co-funded by Lisboa2020 and FCT ( LISBOA-01-0145-FEDER-022170 ). Funding Information: In the published paper, the funding from FEDER under the Lisboa2020 Partnership Agreement was incorrectly noted. This has now been corrected in the section below. The authors apologize for the error. Publisher Copyright: © 2023 The Author(s)(Neuron 106, 778–788.e1–e6; June 3, 2020) In the published paper, the funding from FEDER under the Lisboa2020 Partnership Agreement was incorrectly noted. This has now been corrected in the section below. The authors apologize for the error.publishersversionpublishe
High voltage and optically coupled analogue interface circuits for gas proportional scintillation counters
No full textPrevalência de mineralização aórtica detectada no abate de bovinos no estado de Minas Gerais, Brasil Prevalence of aortic mineralization in slaughtered bovine from the state of Minas Gerais, Brazil
No full textDescreve-se a prevalência da mineralização aórtica em bovinos abatidos em frigorífico de Belo Horizonte, MG. Foram examinados 783 fragmentos de aorta torácica de bovinos de diferentes grupos raciais, sexo e idades. As lesões foram caracterizadas em: grau I, grau II, grau III ou grau IV, baseado na intensidade das alterações macroscópicas. Duzentas e noventa e oito (38,1%) aortas foram classificadas com algum tipo de lesão: 180 com grau I (23,0%), 59 com grau II (7,5%), 35 com grau III (4,5%) e 24 com grau IV (3,1%). Houve diferenças nas freqüências de mineralização aórtica quanto ao sexo, a idade e a raça. Fêmeas e machos castrados (54,6% e 50,7%, PThis study describes the prevalence of aortic mineralization in slaughtered bovine in the state of Minas Gerais. Fragments of thoracic aorta from 783 animals from different origin, breed, gender and age were evaluated macroscopically. All lesions were characterized and divided in, grade I, grade II, grade III and grade IV, depending on the severity of the lesions. A total of 298 (38.1%) aortas had lesions, as follow: 180 grade I (23.0%), 59 grade II (7.5%), 35 grade III (4.5%) and 24 grade IV (3.1%). Differences concerning age, breed and sex were observed. Females and castrated males (54.6% and 50.7%, P<0.00001 and P<0.0001, respectively) compared to intact males, zebu-crossbred and mixed bred (59.3% and 47.8%, P<0.02 and P<0.05, respectively) compared to pure zebu (37,4%) and animals older then 3 years (59.4%, P<0.0001) compared to animals 2-3 years or under 2 years of age (21.7% and 13.9%, respectively) were more frequently affected by aortic mineralization
Major Ecommerce Focus on Product Management Future
No full textIn recent years, people’s acceptance of online shopping has increased markedly with the gradual maturing of e-commerce. This paper aims to propose an ecommerce platform for furniture stores that suits small and medium businesses to expand choice and convenience, allowing customers to buy from a wide array of products with the click of a button. Although there are many existing ecommerce systems in the market, our proposed system stands out for its user experience. This proposed system focuses mainly on four main functions: product management, order management, order-review management, and user management. The current research has been undertaken to walk you through the literature view, methodology, functional overview of the proposed ecommerce system, and discussion. The study further examines the key variables imperative for the success of the proposed system. The findings of this study afford practical implications for the improvement of the online shopping experience of consumers for furniture companies
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