1,721,043 research outputs found
Comment on: Influence of cardiometabolic medications on abdominal aortic aneurysm growth in the UK Aneurysm Growth Study: metformin and angiotensin-converting enzyme inhibitors associated with slower aneurysm growth
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Nellix. The EVAS innovation
No full textThe purpose of this book is to assess the efficacy of the Nellix endoprosthesis in the treatment of patients with AAA, underlining the characteristics, the modalities of implantation, all the possible indications according to the IFUs suggested by the manufacturer and outside the same, the limits related to the implant and the monitoring procedures during the follow-up of the treated patients. Only long-term results will allow a complete and definitive assessment on the real possibilities of use of Nellix, but the data collected from the current experiences of the single centers and those of the trials are very encouraging and promising for an adequate and safe use of this endoprosthesis in the treatment fo aortic aneurismal disease./Contents/Evolution from EVAR to EVAS /Nellix: the implant technique /Evolution of Nellix indications for use /Percutaneous approach using Nellix device /Nellix® EVAS system to treat ruptured aorto-iliac aneurysms /Nellix EVAS system in concomitant iliac aneurysm /Follow-up after Nellix endovascular aneurysm sealing /Complications and secondary interventions after endovascular aneurysm sac sealing with Nellix® /Comparison between aneurysm sac embolization during EVAR and use of Nellix in the prevention of type II endoleak /Nellix endosystem for reintervention after EVAR /Nellix EVAS in combination with parallel graft (ChEVAS) for the treatment of type I endoleaks /Uncovered chimney stent graft for renal arteries using the Nellix endovascular aneurysm sealing technique /Chimney technique with Nellix Endovascular Aneurysm Sealing System (ChEVAS) in the treatment of the Juxtarenal abdominal aortic aneurysm. The personal experience of a single center /Inflammatory response with Nellix endovascular aneurysm sealing /The worldwide experience with the Nellix endosystem: the main multicenter studies /Foreword /CLINICAL CASES/One year follow-up after triple chimney with EVAS in a case of aorto-iliac aneurysm and blister of left renal artery /Recurrent anastomotic aortic pseudoaneurysm: relining with Nellix EVAS Stent System /The peculiar case of a type Is1 endoleak after Nellix endovascular aneurysm sac sealing: clinical presentation and management /Urgent treatment of proximal para-anastomotic aortic aneurysm using Nellix EVAS system and covered stent with chimney technique /Simultaneous treatment of a pararenal and iliac aneurysm in a patient with a previous unsuccessful multilayer flow modulator iliac stenting /Three solutions to three different problems where the Nellix device can be a resource /EVAS relining and chimney (ChEVAS) for late EVAR failure with proximal type I endoleak /Endovascular sealing of an aortocaval fistula in abdominal aortic aneurysm rupture /Management of type Is2 endoleak after EVAS /Clinic casetriple ChEVAS in patient with pararenal aneurys
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Chimney Stenting Versus Surgical Debranching for the Treatment of Aortic Arch Pathologies-A Propensity-Matched Analysis
No full textEndovascular repair of aortic arch lesions requires revascularization of epiaortic vessels in case of coverage. The objective of this study was to compare the outcomes of surgical bypass versus endovascular reconstruction with a chimney graft
Balloon Inducted Re-Lamination and False lUmen Thrombosis in Chronic Type B Aortic Dissection: Technique and Long-Term Results
No full textBackground: To evaluate the safety, feasibility, and effectiveness of the BAlloon Inducted re-Lamination and false lUmen Thrombosis (BAILOUT) as a simple technique to address the retrograde false lumen (FL) perfusion and subsequent aneurysmatic degeneration of the thoracic aorta due to a stent-graft crimped in a small true lumen in chronic Type B dissections. Methods: An observational, retrospective, single-center study analyzing a nonconsecutive cohort of 8 patients affected by chronic type B aortic dissections already treated with thoracic endovascular repair and with an FL lumen backflow corrected with BAILOUT between 2006 and 2020. After a standard distal extension of the previously implanted graft, the distal end of the graft area was ballooned to completely rupture the dissection lamella to relaminate the aorta hindering the FL backflow. Computed tomography was routinely performed within the first postoperative week before discharge and then at 3 months, at 6 months, and yearly thereafter. The technical and clinical success rates were analyzed. Primary outcomes were safety and feasibility of the technique, secondary ones included FL thrombosis evaluation, and total aortic diameter analysis at the above-defined levels during the follow-up. Safety was defined if clinical success was reached. Feasibility was intended as technical success obtention. Results: The technical and clinical success achieved was 100% with the complete interruption of FL backflow stating the safety and feasibility of the BAILOUT technique. No early procedure reinterventions were recorded and during a median follow-up of 62.5 months [interquartile range 43.2-94.1], only 1 death unrelated to the procedure was recorded. Freedom from aortic-related adverse events at 1 month, 3 months, 1 year, 5, and 7 years was 87.5%, 62.5%, 62.5%, 62.5%, and 62.5%, respectively. During the follow-up, no one increment of the diameter of the thoracic aorta was documented and all the patients at 3 years of computed tomography angiography showed a complete FL thrombosis. Conclusions: The BAILOUT technique demonstrates to be safe and feasible in this small cohort of patients as a simple and quick way to overcome the issue of FL backflow in chronic type B dissection. Small cohort and retrospective designs were limitations of the study
Transcranial Doppler detects micro emboli in patients with asymptomatic carotid stenoses undergoing endarterectomy
No full textObjective: The objective of this study was to assess the primary endpoint defined as the detection of micro-embolic signals (MES) by the use of transcranial Doppler (TCD) in patients with asymptomatic carotid stenosis (≥70%) scheduled for carotid endarterectomy. The secondary endpoint consisted of testing the association of MES with stenosis severity, histopathological, and ultrasound characteristics. Methods: This was a single-center, single-arm, prospective, observational trial. Computed tomography angiography and ultrasound assessment (Geroulakos classification) were mandatory as well as being under best medical therapy. MES number and characteristics were investigated in Holter mode TCD-X device with a standard 1.5 MHz probe. The time points of evaluation were: 24 hours preoperative, 24 hours postoperative, and 30 days postoperative. The histopathological analysis was performed according to the modified American Heart Association classification. One-way analysis of variance tested MES differences over time. Univariable and multivariable logistic regression tested variables potentially associated with MES. Results: A total of 120 patients demonstrated a significant reduction of the mean number of MES (3.35 ± 10.04 and 0.82 ± 2.39; pre- and post-carotid endarterectomy, respectively), becoming undetectable at 30 days (P = .001). Hypoechogenic plaques assessed by ultrasound were a significant risk factor for MES (P = .001). The features of plaque vulnerability, such as hemorrhagic component (P = .011), neovascularization (P = .025), signs of inflammation (P = .027), and rupture of the fibrous cap (P = .002) were predictors of MES. Cap rupture was the only predictor in the multivariate analysis (odds ratio, 5.98; P = .030). The stenosis severity was not associated with MES (P = .95) CONCLUSIONS: Patients under best medical therapy had a preoperative embolic activity becoming no more detectable after surgery. Both ultrasound and histologic markers of vulnerability were predictors of MES, and stenosis severity was not associated. TCD gives better insight into the real embolic risk, and future studies should evaluate clinical results coming from its implementation with standard imaging techniques. Clinicaltrial: gov registration number NCT05134493
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