1,354,657 research outputs found
Correction to: Adiponectin in Cerebrospinal Fluid from Patients Affected by Multiple Sclerosis Is Correlated with the Progression and Severity of Disease (Molecular Neurobiology, (2021), 58, 6, (2663-2670), 10.1007/s12035-021-02287-z)
No full textThe original version of this article unfortunately contained some mistakes. The surnames and given names of authors were interchanged. It should be: Elisabetta Signoriello, Marta Mallardo, Ersilia Nigro, Rita Polito, Sara Casertano, Andrea Di Pietro, Marcella Coletta, Maria Ludovica Monaco, Fabiana Rossi, Giacomo Lus, and Aurora Daniele The original article has been corrected
Philosophia moralis
No full textTit. en antep.: "Philosophiae christianae cum antiqua et nova comparatae / a (Nuntio Can. Signoriello concinnatae) et in compendium redactae pars alteraSegunda part. con port. y pag. propiasEnc. 2 t. en 1 vContiene: Pars I. Ethica generalis -- Pars II. Ethica speciali
Treatment withdrawal in relapsing-remitting multiple sclerosis: a retrospective cohort study
No full textTo investigate the effect of drug withdrawal on the course of relapsing-remitting multiple sclerosis (RR-MS)
Specific Association of Teratogen and Toxicant Metals in Hair of Newborns with Congenital Birth Defects or Developmentally Premature Birth in a Cohort of Couples with Documented Parental Exposure to Military Attacks: Observational Study at Al Shifa Hospital, Gaza, Palestine
No full textLocal energy planning: how to get started with Markal while serving the community and interconnecting University¿s expertise with the territory
No full textLevetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats.
No full textDespite anticonvulsant efficacy in animal models of generalized epilepsy, levetiracetam was not
effective in the maximal subcutaneous PTZ model in mice and rats.
Aim of this study was to assess the efficacy of levetiracetam (LEV) against submaximal, s.c. MET test
(PTZ at the dose of 70 mg/kg) acute seizures in Wistar rats, in comparison to valproic acid (VPA).
Thirty male Wistar rats (P42) were divided in three drug-treatment groups (10 rats in each group) as
follows: valproic acid, levetiracetam, and controls. All animals were tested for seizure threshold at age
P50. VPA (110 mg/kg) and LEV (108 mg/kg) were freshly dissolved in saline and injected i.p. in 2–3 ml/kg,
15 and 30 min, respectively, before pentylenetetrazol (PTZ) injection at the dose of 70 mg/kg.
The average latency of the seizure type 3 (generalized clonic seizure with loss of righting reflexes)
significantly differed between controls and the drug-treated animal groups (p 0.02). The average
duration of the seizure type 2 (threshold seizure) was significantly longer in both groups compared to
controls (<0.02).
In conclusion, LEV plays a role against seizures triggered by subcutaneous PTZ injection given at
submaximal doses in rats, as demonstrated by a significant increase in duration of the seizure type 2
(threshold seizure)
Hierarchical Clustering of histogram data using a "model data" based approach
No full textHistogram data are usually used to represent complex phenomena for which is known not only the range of variability but even the inner variability. Several authors have proposed methods to analyze histogram data taking into account frequencies or density probability. In this paper we propose a different way to analyze histogram data. The idea is to take into account histogram shape. In doing that we propose to approximate histogram by a suitable mathematical model and to use model parameters to analyze phenomena described by means of histogram data. In particular, we will show how to transform histogram data in model data and subsequently how to do a cluster analysis on this data
Exploitation of Brillouin spectroscopy for the characterization of a silica film
No full textMeasurement of the elastic properties of micrometric layers is important for MEMS design and manufacturing. Brillouin scattering, the scattering of light by ultrasonic waves, offers the possibility to probe the propagation of acoustic excitations of sub-micrometric wavelength, by contact-less and local measurements. From the acoustic properties the elastic ones can be derived. In the case of transparent supported films bulk waves can be measured in two different scattering geometries, together with surface acoustic waves. The smallness of the probed wavelengths allows a spatial resolution not achievable by other ultrasonic techniques. Brillouin scattering has been exploited to characterize a silica layer of micrometric thickness, thermally grown on a silicon substrate. The observation of various acoustic modes allows to derive the values of all the elastic moduli and of Poisson’s ratio of the silica film, together with its refractive index
Central/diffuse abdominal perception of urological pain in children.
No full textAim: In children with recurrent abdominal pain (RAP), the location of pain to the flank may suggest the involvement of the
urinary apparatus. We aimed to evaluate the location of pain in different age groups of children with idiopathic
hypercalciuria (HC) and/or hyperuricosuria (HU) and RAP. Methods: Location of pain was assessed in 180 consecutive
HC/HU children with RAP, aged 3*/17.6 y, presenting to a single centre. Results : Considering four age groups, central/
diffuse was more prevalent than lateral location of pain in youngsters, with a progressive and significant (pB/0.0001, x2 test
for trend) decrease of the prevalence of central/diffuse location with rising age, and with the most relevant drop after age 8 y.
Location of pain was central/diffuse in 81% of patients under and lateral in 79% of those over 8 y of age (pB/0.0001). The
location of pain changed from central/diffuse to lateral in 16/18 children followed at least 1 y, within 1 to 2 y by age 8.
Conclusion: Only after 8 y of age did the lateral location of abdominal pain become the rule in children with HC/HU and
RAP. This has to be kept in mind in order to avoid overlooking the urologic origin of pain
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