60 research outputs found
Corrigendum: Thalassemia, biobanking infrastructures, and personalized stem cell therapies in Chennai
No full textA Corrigendum onThalassemia, biobanking infrastructures, and personalized stem cell therapies in Chennaiby Panwar, A. (2023). Front. Sociol. 8:1057220. doi: 10.3389/fsoc.2023.1057220In the published article, there was an error in the Funding statement. The Funding statement displayed did not acknowledge UKRI/NERC funding during preparation of the article. The correct statement is “The author also acknowledges support from the NERC grant (NE/T013230/1) during preparation of this article.” The correct Funding statement appears below.<br/
Role of Haridra as an Anti-Depressant
No full textDepression is characterized by decreased interest in daily activities, irritation and low concentration for extended periods. It is the leading causes of disability and 2nd leading cause of death (by suicide) in world with a prevalence rate of 5% of the world’s adult population according to World Health Organization. However, due to stigma, a lack of effective treatments, and a dearth of mental health resources, it is frequently misdiagnosed and untreated. Haridra also identified as Curcuma Longa in Latin is one of the Ayurvedic drug which can be pivotal in treatment in depression as well as easily available, cost effective in long run with virtually no side effects. Curcumin present in Haridra is proven to be effective antidepressant. It is effective in regulating the levels of neurotransmitters, insulin resistance, oxidative and nitrosative stress, hypothalamic-pituitary-adrenal disruptions, and modulate inflammatory pathways, excitotoxicity, neuroplasticity and the endocannabinoid system. We will go over Haridra’s effects through its phytoconstituent curcumin and how it affects the etiopathogenesis of depression in this review
Nanoparticle integrated guar gum hydrogel-based immunosensor for biomedical application
No full textThis paper contains results of studies related to fabrication of nanostructured metal oxide (MO) doped guar gum hydrogel (GGH) based immunosensing platform for detection of oral cancer biomarker (CYFRA-21–1). First, we synthesized nanostructured zirconia (nZrO2) through hydrothermal process and thereafter it has been functionalized with serine amino acid. The GGH has been synthesized through chemical process. Further, the solution of nZrO2 was mixed with GGH in 1:1 ratio in ddH2O. The prepared mixture has been further deposited onto a pre-hydrolyzed indium oxide (ITO) coated glass electrode through drop cast method. The anti-CYFRA-21–1 has been immobilized through EDC-NHS chemistry and Bovine Serum Albumin (BSA) has been used for blocking of nonspecific binding sites. X-Ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR) have been used to investigate morphological as well as functional characterization of synthesized material. However, electrochemical studies have been used to characterize fabricated electrodes as well as response studies. The fabricated immunoelectrode (BSA/anti-CYFRA-21–1/Serine/nZrO2/Hydrogel/ITO) exhibits a wider linear detection range (2.5–80 ng mL−1), remarkably high sensitivity (0.86 µA mg−1 mL cm−2) with shelf life up to 48 days. The electrochemical response studies of fabricated electrode have been further validated through enzyme-linked immunosorbent assay (ELISA) on to obtained saliva sample of oral cancer patients. Oral cancer biomarker detection is key for early diagnosis, personalized treatment, monitoring, enabling timely interventions and improved patient outcomes. We can easily investigate the stage of oral cancer through the detection of concentration of biomarkers secreted in saliva sample of oral cancer patients
Energy bands and density of states of B1-XTMXP (TM = Cr, Fe and Co; X = 0 and 0.25) using FP-LAPW scheme
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WOUND HEALING POTENTIAL OF METHANOLIC EXTRACT OF FLOWERS OF BUTEA MONOSPERMA LINN. IN DIABETIC ANIMALS
No full textThe main of our study is to evaluate the Wound Healing Potential of Methanolic Extract of Flowers of Butea monosperma Linn. in Diabetic Animals. Methanolic extract was prepared by continuous hot extraction method by soxhlet apparatus. Preliminary phytochemical screening showed the presence of flavonoids, phenolic compounds and some glycosides. Diabetes was induced by single injection of Alloxan monohydrate in Wistar albino rats and their blood glucose levels were measured. Excision wound model was used for creation of wound in diabetic animals and methanolic extract was administered in diabetic animals to observe its effect. Methanolic extract significantly lowered the blood glucose level and highly significantly showed wound contraction in diabetic animals. The preliminary phytochemical analysis of the Butea monosperma flower extract showed the presence of tannins, flavonoids and triterpenoids. As per previous literature survey, flavonoids are responsible for anti-diabetic and wound healing activity. So this wound healing effect of Butea monosperma may be due to presence of flavonoids in plant. Hence present research supports traditional claims of the plant in wound healing.
Keywords: Butea monosperma, Diabetic animals, Alloxan monohydrate, Methanolic Extract, Wound Are
Optimization of Xylanase Production from Bacillus Sp. Pkd-9 under Solid State Fermentation, Partial Characterization and Application
No full textThis Dissertation / Report is the outcome of investigation carried out by the creator(s) / author(s) at the department/division of Central Food Technological Research Institute (CFTRI), Mysore mentioned below in this page
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