1,722,403 research outputs found

    An immunohistochemical study of the endocrine pancreas in raptors

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    The cytoarchitecture of the endocrine pancreas of 10 raptors (golden eagles, peregrine falcons, Saker falcon, turkey vultures, red-tailed hawk and unspecified falcon) was examined by immunohistochemistry. Three islet types were identified: type A mixed islets composed mainly by glucagon (A)-secreting cells, type B mixed islets with predominantly insulin (B)-secreting cell component and type M mixed islets (type M) consisting of variable number of glucagon-, insulin- and somatostatin (D)-secreting cells. The latter were further characterized into Type I, II or III according to the cell distribution of the three cell types. A and D cells were also randomly scattered within the exocrine pancreas. The results of this study suggest that the classical concept in birds of a segregation of A and B cells in well-defined and distinct islets is not applicable in raptors, reflecting an evolutionary adaptation to different dietary habits and variation in developmental mechanisms

    ESOC 2023 abstract book: benefits of Zio patch monitoring in detecting early atrial fibrillation after stroke

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    Background and aims: Atrial fibrillation (AF) causes up to 30% of ischaemic stroke, and earlier detection results in faster anticoagulation reducing stroke recurrence. We compared conventional Holter monitoring with Zio patches to assess detection rates, time from request to result, and the impact on outpatient appointments.Methods: we retrospectively compared 339 patients who underwent standard Holter monitoring with 349 patients who had a Zio patch applied for 14 days. Zio patches were fitted as inpatients or sent to patients’ homes for self-application, whereas Holter monitoring required separate hospital attendance for fitting and removal.Results: AF was detected in 7.2% in the Zio group compared with 3.2% in the Holter group. 32% of AF was detected in Zio patches applied within 48hrs of stroke, suggesting a benefit from early hyperacute monitoring. With Holter, average time from referral to test was 42 days and 58 days to result, compared with 29 days and 51 days with Zio. With Zio, mean time to AF detection was 6.3 days and wear time 13.4/14 days (95% of target wear time). 41% of patients with Holter monitoring needed face to face follow-up cardiology appointments compared with 19% with Zio.Conclusions: Zio patches detected more than double the rates of AF compared with usual Holter monitoring. Diagnostic yield was highest within 48hrs of stroke. Time to result was faster, with earlier anticoagulation. Patients did not need to attend hospital for Zio patch fitting and the need for follow up appointments was halved compared with usual monitoring

    Pathology of mycobacteriosis in birds

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    Avian mycobacteriosis is a disease that affects companion, captive exotic, wild, and domestic birds. The disease in birds is generally caused by Mycobacterium avium subsp avium but more than 10 other species of mycobacteria infect birds. Oral route of infection appears to be the primary mode of transmission. In some cases, the extensive involvement of the respiratory system suggests an airborne mode of transmission. Molecular diagnostic techniques have improved the ability to confirm the disease. Avian mycobacteriosis is an important veterinary and economic risk in birds and mammals. Exposure of humans to infected birds may cause a zoonotic infection. [...

    sj-pdf-1-vet-10.1177_03009858231162905 – Supplemental material for Unusual cases of chlamydiosis in psittacine birds

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    Supplemental material, sj-pdf-1-vet-10.1177_03009858231162905 for Unusual cases of chlamydiosis in psittacine birds by Audra L. Walsh and H. L. Shivaprasad in Veterinary Pathology</p

    The optimal grammar of code-switching between Kannada and English

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    Through this study I argue that code-switching between Kannada and English follows the five socio-cognitive constraints- FAITH, POWER, SOLIDARITY, FACE and PERSPECTIVE provided in Bhatt and Bolonyai (2011). Informal semi-structured interviews were conducted among Kannada speaking young adults in urban and semi-urban Karnataka. The results show that they code-switch between Kannada and English at intra-sentential and inter-sentential levels to reflect their traditional-modern and local-global identity. Although the extent of code-switching is quite high, making the code-switched variety the unmarked variety in conversations among the members of this group, the placement and the content of the switches show that the five principles still control the grammar of these bilinguals. The interaction of these principles gives rise to a ranking amongst them which accounts for the uniqueness of the grammar of code-switching between Kannada and English of this speech community.Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2015-07-22 without embargo termsThe student, Chaitra Shivaprasad, accepted the attached license on 2015-05-01 at 01:21.The student, Chaitra Shivaprasad, submitted this Thesis for approval on 2015-05-01 at 01:23.This Thesis was approved for publication on 2015-05-01 at 16:41.DSpace SAF Submission Ingestion Package generated from Vireo submission #8100 on 2015-07-22 at 10:34:00Made available in DSpace on 2015-07-22T22:17:42Z (GMT). No. of bitstreams: 2 CHAITRASHIVAPRASAD-THESIS-2015.pdf: 929109 bytes, checksum: 0e53d6438266f80b664723d42bad416d (MD5) LICENSE.txt: 4224 bytes, checksum: e882044c9551c51bfb7d73ab105dbe78 (MD5) Previous issue date: 2015-05-01File replaces and embargo restriction lifted by Alexis Thompson at the Graduate College. See archived OTRS Ticket #2016092928000303. New file uploaded and restrictions lifted by kappleg2 2016-10-04.Ope

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Myopathy of the pipping muscles, hepatosis dietetica, and cataracts in emu chicks (Dromaius novaehollandiae)

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    Seven emu chicks (Dromaius novaehollandiae) from a farm with poor hatchability (16-18%) and increased neonatal mortality were presented for necropsy with a history of death at or within a few days after hatching. Macroscopic examination revealed subcutaneous edema and hemorrhages and swelling of the pipping muscles in the proximal neck (71%), pale liver with hemorrhages (71%), noninternalized residual yolk sac (86%) and anasarca (14%). Histologically, the most remarkable findings were necrosis of the musculus complexus (100%) of the pipping muscles, as well as myocardial necrosis and mineralization (29%). Liver contained severe multifocal hepatocellular necrosis and hemorrhages (57%), and both eyes exhibited swollen and vacuolated lenticular fibers in 5 chicks (100%) in which the eyes were examined. The lesions observed here are suggestive of a nutritional deficiency. The deficiency was confirmed by finding low levels of vitamin E in the liver, and vitamin E and vitamin A levels in the feed

    Supplemental Material, sj-pdf-1-vet-10.1177_03009858211035388 - Infectious laryngotracheitis of chickens: Pathologic and immunohistochemistry findings

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    Supplemental Material, sj-pdf-1-vet-10.1177_03009858211035388 for Infectious laryngotracheitis of chickens: Pathologic and immunohistochemistry findings by Silvia Carnaccini, Chiara Palmieri, Simone Stoute, Manuela Crispo and H. L. Shivaprasad in Veterinary Pathology</p

    Pathological and Biochemical Studies of Mucopolysaccharidosis Type IIIB (Sanfilippo Syndrome Type B) in Juvenile Emus (Dromaius novaehollandiae)

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    Mucopolysaccharidosis (MPS) type IIIB was diagnosed in 14 juvenile emus (Dromaius novaehollandiae), ages 3 weeks to 6 months, based on pathological and biochemical analyses. The animals had a history of neurological signs or sudden death; one of the birds with neurological signs and 3 others experienced acute hemoabdomen. Histopathologically, neuronal swelling and vacuolation in the cerebrum, cerebellum, brainstem, and spinal cord (80%-92%); retina (100%); autonomic ganglia of the intestine (71%); gizzard (50%); adrenal gland (27%); and ear (50%) were noted in affected but not healthy emus. Cytoplasmic vacuoles were also observed in the pancreas, liver, intestine, adrenal glands, and kidneys. The intracytoplasmic inclusions were periodic acid-Schiff and Luxol Fast Blue positive, consistent with a storage disease. Foamy macrophages infiltrated the liver, intestine, tunica media of the aorta, and spleen. By transmission electron microscopy, typical lamellated cytoplasmic bodies were detected in neurons of the brain and retina, while electron-dense bodies consistent with glycosaminoglycan inclusions were observed in hepatocytes and/or hepatic macrophages. The livers of the 2 affected emus studied contained large amounts of heparan sulfate, which is suggestive of MPS type III. Compared with normal controls, hepatic and serum α-N-acetylglucosaminidase activity was very low (<8% of control), while other enzyme activities were normal to increased in the 2 affected emus studied. Moreover, affected emus were homozygous for a 2-bp deletion in the NAGLU gene. This study characterizes the pathology of MPS type IIIB in emus, which is one of the rare inborn errors in birds, showing the homology of this condition to Sanfilippo syndrome in humans
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