98,364 research outputs found
Joshua Davis: Author of Spare Parts
No full textCitation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University
Steven Johnson Author Talk Poster
No full textK-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book
Magnesium deficiency and cerium promote fibrogenesis in rat heart
No full textCerium is a biologically active lanthanide and a major constituent of monazite. The observation that inhalation of particles of cerium causes pneumoconiosis had generated considerable interest in the toxicology of the element (Venugopal and Luckey 1978; Vocatura et al 1983). Cerium tartrate was found to produce cardiac injury and polycythaemia in small animals (Venugopal and Luckey 1978). More recently, tropical endomyocardial fibrosis (EMF), a restrictive cardiomyopathy, was postulated to be the cardiac expression of cerium toxicity in combination with magnesium deficiency (Valiathan et al 1989; Valiathan and Kartha 1990). The postulation was based upon the observation of elevated levels of cerium and depressed levels of magnesium in the cardiac tissue of patients with EMF (Valiathan et al 1989; Valiathan and Kartha 1990). Studies carried out in pursuance of the hypothesis showed that tissue levels of cerium are enhanced in magnesium deficiency (Eapen et al 1996) and that cerium and magnesium deficiency have a synergistic effect on cardiac metabolism (Gunther 1990; Shivakumar and Renuka Nair 1991). Importantly, recent observations on the mode of action of cerium at the molecular level suggested that the element may influence expression of matrix proteins like collagen in the heart and produce fibrosis (Prakash et al 1995; Shivakumar et al 1992). A sequel to these earlier investigations, the present study examined whether chronic ingestion of low doses of cerium would produce cardiac fibrosis in experimental animals. This communication presents evidence that cerium per se or in combination with magnesium deficiency produces subendocardial fibrosis and increase in interstitial cellularity and collagen content in rat heart. It also confirms the earlier observation from this laboratory that magnesium deficiency promotes accumulation of cerium in the cardiac tissue (Eapen el al 1996)
Krein's method in inverse scattering
No full textA detailed discussion of the Krein’s results (applicable for solving the inverse scattering problem) is given with complete proofs. It is shown that the S-function S(k) used in Krein’s work is the S-matrix used in physics. The basic new results of the paper include the detailed description and analysis of an inversion algorithm based on Krein’s results and a proof of its consistency, that is the proof that the reconstructed potential generates the same scattering data from which it was reconstructed. Numerical advantages of using Krein’s method are discussed
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Analysis and evaluation of mechanical performance of reinforced sandwich structures: X-CorTM and K-CorTM
No full textX-CorTM and K-CorTM are foam based lightweight structural cores reinforced with ZFiber
® rods oriented in a truss pattern. They can generate sandwich structures which
possess strength- and stiffness-to-weight ratios such to compete with aerospace grade
honeycomb constructions. The enhanced tailoring ability to specific design needs, the
flexibility in reinforcement type and arrangement, the variety between closed cell foamfilled
or hollow core configurations for ultimate weight savings or structural
multifunctionality, while utilising manufacturing procedures similar to traditional
honeycomb sandwich structures (low cost out-of-autoclave manufacturing techniques
included) make these novel materials an attractive alternative. The process of their
implementation into current engineering practice requires a parallel comparison with
existing competitor cores and a critical evaluation of their performance, identifying
advantages and disadvantages.
This study represents one of the first attempts to create a rigorous methodology for the
analysis and evaluation of their mechanical behaviour and manufacturing sensitivities.
The balance of out-of-plane properties (shear and compression), fundamental for a
sandwich core material, has been investigated. The material energy absorption capacity
for the aforementioned loading cases, as well as for in-plane crushing was evaluated.
For this purpose, a new quasi-static test for progressive crushing of flat sandwich
laminates was designed successfully. The experimental data gathered validate proposed
analytical models which allowed further deductions on core parameters influence to be
made. Those parameters were the pin insertion angle, pin lay-out, pin density and the
role of the foam. A local-global FE modelling approach for Z-pinned sandwich cores is
also provided and validated for X-CorTM structures. Structural differences between XCorTM
and K-CorTM are at the base of a diverse mechanical response; their performance
is sensitive to the manufacturing process, as it determines the quality of the pin-skin and
pin-adhesive film interfaces. An ‘improved’ manufacturing technique designed for XCorTM
resulted in a sandwich panel able to offer the same mechanical performance of a
Nomex® honeycomb structure for a 25% of weight saving
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Expanding “Communities and Collections” in the K-State Research Exchange (K-REx) to benefit the K-State Community and Beyond
No full textKansas State University has used its institutional repository, the K-State Research Exchange (K-REx), to store and share its first year experience program, K-State First, and notably its common reading program, K-State First Book. We have done so with the aim that the accessibility and preservation of these documents ensures program stability, promotes engagement with first year programming, and provides the ability to foster growth,educational opportunities, and community building outside of K-State. Moving away from research concentrated repositories and taking a more holistic approach to scholarship, especially when realizing the pedagogical significance of collaborative campus programming, institutions can showcase, discover, preserve, and grow programs that shape campus communities and engagement.
This session will provide an overview of K-REx and spotlight the digital archive of the university’s first year experience program and common reading program, K-State First Book. We will discuss the benefits and challenges to expanding the purview of your repositories. We talkthrough the types of materials we decide to host in our repository and why we share what we do. We will also provide recommendations on new ways to evaluate what belongs in institutional repositories and how this diversity can benefit your program, your institution, the community, and others
Ready Player One Program Event Poster
No full textK-State Book NetworkA poster advertising an author talk by Ernest Cline at Kansas State University on October 10, 2013. Ernest Cline's book "Ready Player One" was selected as the 2013-2014 common book
Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution
No full textNon-steroidal anti-inflammatory drugs (NSAIDs) contribute to gastrointestinal ulcer formation by inhibiting epithelial cell migration and mucosal restitution; however, the drug-affected signaling pathways are poorly defined. We investigated whether NSAID inhibition of intestinal epithelial migration is associated with depletion of intracellular polyamines, depolarization of membrane potential (Em) and altered surface expression of K+ channels. Epithelial cell migration in response to the wounding of confluent IEC-6 and IEC-Cdx2 monolayers was reduced by indomethacin (100μM), phenylbutazone (100μM) and NS-398 (100μM) but not by SC-560 (1μM). NSAID-inhibition of intestinal cell migration was not associated with depletion of intracellular polyamines. Treatment of IEC-6 and IEC-Cdx2 cells with indomethacin, phenylbutazone and NS-398 induced significant depolarization of Em, whereas treatment with SC-560 had no effect on Em. The Em of IEC-Cdx2 cells was: −38.5±1.8mV under control conditions; −35.9±1.6mV after treatment with SC-560; −18.8±1.2mV after treatment with indomethacin; and −23.7±1.4mV after treatment with NS-398. Whereas SC-560 had no significant effects on the total cellular expression of Kv1.4 channel protein, indomethacin and NS-398 decreased not only the total cellular expression of Kv1.4, but also the cell surface expression of both Kv1.4 and Kv1.6 channel subunits in IEC-Cdx2. Both Kv1.4 and Kv1.6 channel proteins were immunoprecipitated by Kv1.4 antibody from IEC-Cdx2 lysates, indicating that these subunits co-assemble to form heteromeric Kv channels. These results suggest that NSAID inhibition of epithelial cell migration is independent of polyamine-depletion, and is associated with depolarization of Em and decreased surface expression of heteromeric Kv1 channels.ID: S0006295207001931; M3: Article; Accession Number: S0006295207001931; Author: L.C. Freeman (b); Author: D.F. Narvaez (a); Author: A. McCoy (a); Author: F.B. von Stein (c); Author: S. Young (b); Author: K. Silver (a); Author: S. Ganta (b); Author: D. Koch (b); Author: R. Hunter (b); Author: R.F. Gilmour (c); Author: J.D. Lillich (a, ⁎); Affiliation: Department of Clinical Sciences, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, United States; Affiliation: Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, United States; Keyword: Non-steroidal anti-inflammatory drugs; Keyword: Intestinal epithelial cells; Keyword: Membrane potential; Keyword: Potassium channels; Number of Pages: 12; Language: English;Source type: Electronic(1)http://search.ebscohost.com/login.aspx?direct=true&db=edselp&AN=S0006295207001931&site=eds-live&scope=sit
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