5,189 research outputs found

    RDLS-SS-DWT v. 0.9

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    This fileset contains the implementation of RDLS-DWT and SS-DWT in JPEG 2000 (RDLS-SS-DWT v. 0.9), which was used in a research described in: R. Starosolski, “Application of reversible denoising and lifting steps to DWT in lossless JPEG 2000 for improved bitrates,” Signal Processing: Image Communication, Vol. 39, Part A, pp. 249-63, DOI: 10.1016/j.image.2015.09.013, 2015 and R. Starosolski, “Skipping selected steps of DWT computation in lossless JPEG 2000 for improved bitrates,” submitted.   This software is intended for research purposes only; it is provided "as is"; author makes no warranty of any kind, either express or implied, with respect to this software. <br

    Global gene expression changes induced in the human placenta during labor

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    Objectives: To gain insight into the process of labor and the effects of labor on placental gene expression, we performed a microarray analysis to identify the differentially expressed transcripts that may participate in labor onset and progression. Methods: We compared expression profiles in placentas from 16 women who underwent elective nonlabored cesarean section and from seven women who underwent vaginal delivery. Oligonucleotide probes representing 55,000 genes were used to measure gene expression. Differential gene expression was evaluated using the Student's t-test and fold change assessment and reverse transcription PCR was used to validate the differentially expressed genes. Results: A total of 351 genes were found to be differentially expressed between the two groups. Among these differentially expressed genes, 344 genes were up-regulated and seven were down-regulated. These differentially expressed genes involved 15 categories including genes involved in stress response, immune response, cell death, coagulation, and blood vessel development which are considered to be most closely associated with the inflammatory response that characterizes labor. Conclusion: A total of 351 differentially expressed genes of 15 categories were found in the placentas of the vaginal delivery group, indicating a diversity of gene expression alteration and complexity in the labor process. These gene expression changes could be a cause of labor onset and progress or simply an effect of labor. © 2010 Elsevier Ltd. All rights reserve

    Theoretical analysis of the magnetocardiographic pattern for reentry wave propagation in a three-dimensional human heart model

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    We present a computational study of reentry wave propagation using electrophysiological models of human cardiac cells and the associated magnetic field map of a human heart. We examined the details of magnetic field variation and related physiological parameters for reentry waves in two-dimensional (2-D) human atrial tissue and a three-dimensional (3-D) human ventricle model. A 3-D mesh system representing the human ventricle was reconstructed from the surface geometry of a human heart. We used existing human cardiac cell models to simulate action potential (AP) propagation in atrial tissue and 3-D ventricular geometry, and a finite element method and the Galerkin approximation to discretize the 3-D domain spatially. The reentry wave was generated using an S1-S2 protocol. The calculations of the magnetic field pattern assumed a horizontally layered conductor for reentry wave propagation in the 3-D ventricle. We also compared the AP and magnetocardiograph (MCG) magnitudes during reentry wave propagation to those during normal wave propagation. The temporal changes in the reentry wave motion and magnetic field map patterns were also analyzed using two well-known MCG parameters: the current dipole direction and strength. The current vector in a reentry wave forms a rotating spiral. We delineated the magnetic field using the changes in the vector angle during a reentry wave, demonstrating that the MCG pattern can be helpful for theoretical analysis of reentry waves. (C) 2007 Elsevier Ltd. All rights reserved

    Dynamic deformation and high velocity impact behaviors of Ti-6Al-4V alloys

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    Deformation behaviors under quasi-static and dynamic compression and high velocity impact condition of Ti-6Al-4V ELI (extra low interstitial) alloys in two different conditions were investigated. Mill annealed (MA) alloy, consisted of equiaxed a, and thermomechanically treated (TMT) alloy, consisted of mixed structure of equiaxed a and transformed β, were prepared. Compression tests were performed in low strain rate regime using hydraulic testing machine and were performed in high strain rate regime using split Hopkinson pressure bar. High velocity impact tests were also performed by impacting the test projectiles made of these alloys against a steel target at a velocity of ∼400m/s. The compression test results showed that deformation behaviors were influenced by the strain hardening exponent at low strain rate regime, and by both the strain hardening exponent and the strain-rate hardening rate at high strain rate regime. TMT alloy showed higher strength but almost similar fracture strain as MA alloy at a high strain rate of ∼6000/s, due to the effect of strain-rate hardening. The high velocity impact test results showed that the projectile of TMT alloy withstood without fracture at higher impact velocity, but the maximum amounts of deformation prior to crack were nearly the same for both alloys. These results were in accord with the results of compression tests at high strain rate regime, that is, higher strength but same fracture strain of TMT alloy compared to MA alloy

    CONSECUTIVE C-C BOND SCISSION OF AN ALLYL LIGAND ON A WOS3 CLUSTER FRAMEWORK

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    The reaction, of Os-3(CO)(9)(C(2)R(2)) (R = Tol, Ph; Tol = p-C(6)H(4)Me) with Cp(CO)(2)W=CTol (Cp = eta(5)-C5H5) produces an alkylidyne-alkyne complex CpWOs(3)(CO)(10)(mu(3)-eta(2)-C(2)R(2))(mu(3)-CTol) [1a (R = Tol), 1b (R = Ph)], which is converted to two isomeric allyl complexes CpWOs(3)(CO)(10)(mu(3)-C(3)R(2)Tol) (2a,b and 3a,b) upon thermolysis. Complexes 3a,b, in which the allyl ligand is pi-coordinated to the tungsten atom, undergo consecutive allyl C-C bond cleavage to afford trialkylidyne complexes CpWOs(3)(CO)(9)(mu(3)-CR)(2)(mu 3-CTol) (5a,b) via alkylidyne-alkyne complex CpWOs(3)(CO)(10)(mu(3)-eta(2)-C(2)R(2))(mu(3)-CTol) or CpWOs(3)(Co)(10)(mu 3-eta(2)-C(2)RTol)(mu(3)-CR) (4a,b), together with formation of CpWOs(3)(CO)(8)(mu(3)-perpendicular to-C(2)R(2))(mu(3)-CTol) or CpWOs(3)(CO)(8)(mu(3)-eta(2)-perpendicular to-C(2)RTol)(mu(3)-CR) (6a,b) as a minor product

    SS Northland Echo

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    Photograph - A view of the steamboat, SS Northland Echo on the Athabasca River. Athabasca, Albert

    SS Athabasca River - 02

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    Photograph - A view of the SS Athabasca River paddle steamer on the river, Athabasca, Albert

    RIC-HSCT for MF/SS

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    Advanced-stage mycosis fungoides and Sezary syndrome (MF/SS) have a poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT), particularly using a reduced-intensity conditioning (RIC) regimen, is a promising treatment for advanced-stage MF/SS. We performed RIC-HSCT in nine patients with advanced MF/SS. With a median follow-up period of 954days after HSCT, the estimated 3-year overall survival was 85.7% (95% confidence interval, 33.4-97.9%) with no non-relapse mortality. Five patients relapsed after RIC-HSCT; however, in four patients whose relapse was detected only from the skin, persistent complete response was achieved in one patient, and the disease was manageable in other three patients by the tapering of immunosuppressants and donor lymphocyte infusion, suggesting that graft-versus-lymphoma effect and "down-staging" effect from advanced stage to early stage by HSCT improve the prognosis of advanced-stage MF/SS. These results suggest that RIC-HSCT is an effective treatment for advanced MF/SS

    Optimization of vibration amplitude ratio of face mill tool of VMC and analysis with design expert to endorsing shim design

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    This paper presents the concept, design and development of shim (passive damper) to improve the stability for high spindle speed machine operation of face mill tool. The objective of this paper is to learning the dynamic behavior of a face mill tool on VMC with dissimilar types of shims which cover investigation of dynamic motion behavior of the face mill tool, the behavior of different types of shim design and behavior of vibration by using the amplitude ratio method and analysis by a Design Expert. Research work supported computational analysis with Ansys, 35 VMC experimental records and analyzed by ANOVA/Design Expert with different type of shims to observe a dynamic behavior of chatter. It include of the effect of process parameters like Cutting speed (250,200,150 m/min), feed per tooth (0.05, 0.1, 0.15mm/tooth), depth of cut (1.2 mm, 1.0 mm, 0.8 mm), and different types of materials (shims) for face mill tool on VMC, for analyzing the responses like amplitude ratio in X – direction, Y- direction with ANOVA and optimizing for AISI 2062 steel by Design Expert. An experimental methodology was developed using the DOE (Design of experiment) technique. The optimum factorial method was used to design an orthogonal array of four factors having three levels. Here, the main results are based on amplitude ratio, ANOVA analysis and optimization. ANOVA was used to decide the effects of the machining parameters on the vibration amplitude ratio in X; and vibration amplitude ratio in Y. This is useful for evaluating the stability of milling operations via time domain FFT and analyzed by ANOVA. Data are validated by 35 sets of VMC experiments. Physical 35 experiments may be not enough in a view of high level researchers, academicians and industrialist to conclude the use of shim and it need in face mill tool on VMC. Hence here optimization based on optimum factorial method is executed using Design Expert software in which 35experiments and its iterations with 70 populations were used to run the program. It is found that the most critical parameter in this study is the material of Shim. At high cutting parameters carbide shim, at low and medium cutting parameters SS shim are given better results by ANOVA and Optimization of Design Expert also validated by 35 sets of VMC experiments. Hence these shim designs endorse versatile solutions
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