6,093 research outputs found
Iris metastasis from systemic cancer in 104 patients: the 2014 Jerry A. Shields Lecture
No full textPurpose: To describe the clinical features, treatment, and outcome of patients with iris metastasis.Methods: Retrospective case series of 160 tumors in 107 eyes of 104 patients with iris metastasis from systemic cancer.Results: The median age at presentation with iris metastasis was 60 years. Iris metastasis was more common in whites (n = 93, 89%) and women (n = 65, 62%). The primary tumor was located in the breast (n = 34, 33%), lung (n = 28, 27%), skin (melanoma) (n = 13, 12%), kidney (n = 7, 7%), esophagus (n = 3, 3%), and others (n = 19, 19%). The main symptoms were pain (n = 33, 32%) or blurred vision (n = 31, 30%). The main findings were corectopia (n = 38, 37%) and secondary glaucoma (n = 38, 37%). The metastasis was unifocal (n = 84, 78%) or multifocal (n = 23, 21%) for a total of 160 tumors. The main tumor was centered at the iris root (n = 72, 69%), midzone (n = 22, 21%), or pupillary margin (n = 10, 10%), with median tumor diameter of 5 mm. Coexistent conjunctival or ciliary body/choroidal metastases were found in 39 patients. Management of iris metastasis included systemic chemotherapy (n = 18, 22%), external beam radiotherapy (n = 34, 41%), plaque radiotherapy (n = 20, 24%), surgical excision (n = 4, 5%), enucleation (n = 3, 4%), or observation (n = 4, 5%). Following treatment, tumor control without recurrence was achieved in 95% cases. In 98 cases with adequate follow-up information, death occurred in 85 (87%) at median 10 months (range, <1-239 months) from the date of iris metastasis.Conclusions: Metastatic tumors to the iris generally originate from primary malignancies in the breast, lung, or skin (melanoma). Despite successful ocular treatment, life prognosis is poor
Visual improvement in amblyopic eye following treatment-induced vision loss in dominant eye with uveal melanoma
No full textVisual improvement in amblyopic eye following treatment induced vision loss in dominant eye with uveal melanoma
No full textVisual improvement in amblyopic eye following treatment-induced vision loss in dominant eye with uveal melanoma
No full textRobinione overstreeti Boyko & Williams & Shields 2017
No full textRobinione overstreeti (Adkison & Heard, 1995) n. comb. Figs 9, 10 Pseudioniinae [sic] sp. A. Rakocinski et al., 1993: 102 (list). Pseudione overstreeti Adkison & Heard, 1995: 105 –109, figs. 1, 2 (type locality: west end of Horn Island, Mississippi, U.S. A, infesting Callichirus islagrande (Schmitt, 1935)).— Rakocinski et al., 1996: 351 (list).— Camp, 1998: 134 (list).— Schotte et al., 2009: 980 (list).— Vogt, 2016: 1409, 1410 (mention), fig. 7A (color photo of male and female). Material examined. United States: Immature female (5.5 mm), ex right branchial chamber of female Callichirus islagrande (10.9 mm CL), Gulf Beach, Isle Dernière, Louisiana, coll. R. B. Griffis & T. Zimmerman, 27 Jul 1993 (ULLZ 10206); immature female (5.5 mm, on SEM stub, USNM 1459847 ex ULLZ 10205), mature male (3.0 mm), ex right branchial chamber of female C. islagrande (8.0 mm CL), mid-intertidal pool and low intertidal, bay side, Isle Dernièrs, Louisiana, coll. R. B. Griffis, D. L. Felder & T. McTigue, 19 Oct 1993 (ULLZ 10205); ovigerous female (11.0 mm), mature male (4.0 mm), ex left branchial chamber of female C. islagrande (11.4 mm CL), Gulf side, Isle Dernièrs, Louisiana, coll. D. L. Felder, P. Klerks & D. Griffis, 22 Jan 1995 (ULLZ 10207); immature female (11.0 mm), mature male (4.0 mm), ex left branchial chamber of female C. islagrande (10.8 mm CL), Gulf side of beach, Isla Dernièrs, Louisiana, coll. R. B. Griffis & T. Zimmerman, 27 Jul 1993 (ULLZ 10199); female (11.0 mm), ex left branchial chamber female C. islagrande (10.1 mm CL), Gulf side of beach, Isle Dernièrs, Louisiana, coll. R. B. Griffis, D. L. Felder & T. McTigue, 19 Oct 1993 (ULLZ 10209); immature female (3.0 mm), ex left branchial chamber of immature C. islagrande (5.0 mm CL), immature female (3.7 mm), mature male (2.3 mm, on SEM stub, USNM 1459848 ex ULLZ 10198), ex left branchial chamber of immature C. islagrande (5.0 mm CL), immature female (3.5 mm), mature male (2.0 mm), ex right branchial chamber of female C. islagrande (6.5 mm CL), immature female (3.5 mm), mature male (2.2 mm, on SEM stub, USNM 145 9848 ex ULLZ 10198), ex right branchial chamber of female C. islagrande (5.0 mm CL), access road #3, near Fish Pass, low tide, morning, Mustang Island, Texas, coll. D. L. Felder & L. Bilodeau, 1 Mar 2000 (ULLZ 10198); ovigerous female (12.0 mm), mature male (4.5 mm), ex C. islagrande (host not in vial with parasites), Gulf side, Isle Dernièrs, Louisiana, coll. D. L. Felder & R. B. Griffis, 24 Jul 1992 (ULLZ 10210); ovigerous female (11.0 mm), mature male (4.5 mm), ex left branchial chamber of female C. santarosaensis Sakai and Türkay, 2012 (11.4 mm CL), bay side, Isle Dernièrs, Louisiana, coll. A. Christian, D. Badgwill, R. B. Griffis & I. A. Griffis, 22 Jan 1993 (ULLZ 10204). Distribution. Gulf of Mexico from west coast of Florida to Texas, U.S.A., and Tabasco, Mexico. Hosts. Callichirus islagrande (Schmitt, 1935) (type species) and C. santarosaensis Sakai & Türkay, 2012. Remarks. The present material of R. overstreeti n. comb. (Figs. 9, 10) matches that of Adkison & Heard (1995), who provided a detailed description of the species. Although they did not show the ventral view of the male, Adkison & Heard (1995) indicated that the pleopods were “vestigial or absent, represented by low mounds mesal to lateral processes of pleomeres” as we found in our samples (Fig. 10D). The male pleomeres documented in Adkison & Heard (1995; Fig. 2A) are slightly more elongate and acute than in the present specimens, but this variation is typical for pleopodal morphology in bopyrids. Each male pereopod of R. overstreeti n. comb. has a recurved dactylus, the distal end of which touches the base of the propodus and is surrounded by a low ridge of tooth-like projections (Fig. 10B, C). The female R. overstreeti n. comb. examined with SEM (Fig. 9) is not fully mature, thus has reduced oostegites and, proportionally, somewhat longer and thinner pleopods and uropods than the holotype (Adkison & Heard, 1995; Fig. 1B). Female and male antennae (Figs. 9B, 10B) have the same numbers of articles as in the original description (3 and 4 for females; 3 and 5 for males). Female R. overstreeti n. comb. have pereopods with elongate carpi and a large irregular, infolded mass on the dorsal surface of each of the bases (Fig. 9C, D), all pereopodal segments covered with scales (Fig. 9C–F). Felder & Dworschak (2015) discussed in detail the nomenclatural issues surrounding the name C. santarosaensis, which is now used for Gulf of Mexico populations of the Callichirus species formerly called C. major (Say, 1818), but which is distinct from that Atlantic coastal species. This is the first record of “ Pseudione ” overstreeti from C. santarosaensis (either under that name or as C. major). Adkison & Heard (1995) examined several hundred C. santarosaensis (as C. major) and found no bopyrids on them; it is not clear where their specimens were collected from, but based on the material examined list for P. overstreeti, they probably came from Alabama or Mississippi.Published as part of Boyko, Christopher B., Williams, Jason D. & Shields, Jeffrey D., 2017, Parasites (Isopoda: Epicaridea and Nematoda) from ghost and mud shrimp (Decapoda: Axiidea and Gebiidea) with descriptions of a new genus and a new species of bopyrid isopod and clarification of Pseudione Kossmann, 1881, pp. 251-301 in Zootaxa 4365 (3) on pages 279-282, DOI: 10.11646/zootaxa.4365.3.1, http://zenodo.org/record/111798
STUDY OF THE MAGNETIC FIELD OF THREE PHASE LINES OF SINGLE CORE POWER CABLES WITH TWO-END BONDING OF THEIR SHIELDS
No full textThe study tested the process of the magnetic field (MF) mitigation in the HV three-phase power cable lines (CL) made of single core cables in two-ends bonding of their shields. Developed the technique of numerical simulation and calculation of the MF of CL based on its axisymmetric calculation model using the finite element method that allowed to describe the condition of closing the cable shields at the both ends of the CL and solve the problem in two-dimensional formulation. The authors show the possibility of MF mitigation of the three-phase CL by increasing the cross-section of closed cable shields, which in some cases may be an alternative to external electromagnetic shields. Obtained and experimentally validated in laboratory and field conditions with an accuracy of no more than 5 % the value of mitigation coefficients of MF of three-phase three-wire CL in two-ends bonding of their shields depending on the technical parameters of the cables and the geometry of their installation, which is important for the design of new cable power lines. Their values are in the range from 0.99 to 0.32 when the cross sections of cable shields are from 25 mm2 to 200 mm2 and the distance between the axes of the cables are from 0.1 to 0.5 m. The results show the ability to execute design of cable power lines in residential areas, taking into account both the sanitary standards of the MF, as well as to energy efficiency
Study of the magnetic field of three phase lines of single core power cables with two-end bonding of their shields
No full textИсследован процесс ослабления магнитного поля (МП) высоковольтной кабельной линий (КЛ) из одножильных кабелей при двухстороннем заземлении их экранов. Разработана методика численного моделирования и расчета МП КЛ на основе метода конечных элементов с применением осесиммеричной расчетной модели КЛ, что позволило описать условие замыкания экранов кабелей на концах КЛ и решить задачу в двумерной постановке. Получены точные и экспериментально обоснованные значения коэффициентов ослабления МП КЛ при двустороннем заземлении экранов в зависимости от технических характеристик кабелей и геометрии их укладки.The study tested the process of the magnetic field (MF) mitigation in the HV three-phase power cable lines (CL) made of single core cables in two-ends bonding of their shields. Developed the technique of numerical simulation and calculation of the MF of CL based on its axisymmetric calculation model using the finite element method that allowed to describe the condition of closing the cable shields at the both ends of the CL and solve the problem in two-dimensional formulation. The authors show the possibility of MF mitigation of the three-phase CL by increasing the cross-section of closed cable shields, which in some cases may be an alternative to external electromagnetic shields. Obtained and experimentally validated in laboratory and field conditions with an accuracy of no more than 5 % the value of mitigation coefficients of MF of three-phase three-wire CL in twoends bonding of their shields depending on the technical parameters of the cables and the geometry of their installation, which is important for the design of new cable power lines. Their values are in the range from 0.99 to 0.32 when the cross sections of cable shields are from 25 mm² to 200 mm² and the distance between the axes of the cables are from 0.1 to 0.5 m. The results show the ability to execute design of cable power lines in residential areas, taking into account both the sanitary standards of the MF, as well as to energy efficiency
Open access self-archiving: An author study
No full textThis, our second author international, cross-disciplinary study on open access had 1296 respondents. Its focus was on self-archiving. Almost half (49%) of the respondent population have self-archived at least one article during the last three years. Use of institutional repositories for this purpose has doubled and usage has increased by almost 60% for subject-based repositories. Self-archiving activity is greatest amongst those who publish the largest number of papers. There is still a substantial proportion of authors unaware of the possibility of providing open access to their work by self-archiving. Of the authors who have not yet self-archived any articles, 71% remain unaware of the option. With 49% of the author population having self-archived in some way, this means that 36% of the total author population (71% of the remaining 51%), has not yet been appraised of this way of providing open access. Authors have frequently expressed reluctance to self-archive because of the perceived time required and possible technical difficulties in carrying out this activity, yet findings here show that only 20% of authors found some degree of difficulty with the first act of depositing an article in a repository, and that this dropped to 9% for subsequent deposits. Another author worry is about infringing agreed copyright agreements with publishers, yet only 10% of authors currently know of the SHERPA/RoMEO list of publisher permissions policies with respect to self-archiving, where clear guidance as to what a publisher permits is provided. Where it is not known if permission is required, however, authors are not seeking it and are self-archiving without it. Communicating their results to peers remains the primary reason for scholars publishing their work; in other words,
researchers publish to have an impact on their field. The vast majority of authors (81%) would willingly comply with a mandate from their employer or research funder to deposit copies of their articles in an institutional or subject-based repository. A further 13% would comply reluctantly; 5% would not comply with such a mandate
Progress of international hydrogen production network for the thermochemical Cu–Cl cycle
No full textThis paper presents recent advances by an international team which is developing the thermochemical copper–chlorine (Cu–Cl) cycle for hydrogen production. Development of the Cu–Cl cycle has been pursued by several countries within the framework of the Generation IV International Forum (GIF) for hydrogen production with the next generation of nuclear reactors. Due to its lower temperature requirements in comparison with other thermochemical cycles, the Cu–Cl cycle is particularly well matched with Canada's Generation IV reactor, SCWR (Super-Critical Water Reactor), as well as other heat sources such as solar energy or industrial waste heat. In this paper, recent developments of the Cu–Cl cycle are presented, specifically involving unit operation experiments, corrosion resistant materials and system integration.Atomic Energy of Canada LimitedOntario Research Excellence FundNatural Sciences and Engineering Research Council of CanadaUniversity Network of Excellence in Nuclear Engineering (UNENE)Canada Research Chairs progra
ŻYCIE UKRYTE W SŁOWIE. "BEKSIŃSCY. PORTRET PODWÓJNY" MAGDALENY GRZEBIAŁKOWSKIEJ W ŚWIETLE POSTSTRUKTURALIZMU
No full textLife Hidden in Words. Magdalena Grzebiałkowska\u27s "Beksińscy. Portret podwójny" and Poststructuralism
The article analyzes Magdalena Grzebiałkowska\u27s biographical "Beksińscy. Portret podwójny" which focuses on the lives of Zdzisław Beksiński and Tomasz Beksiński. The author looks at the construction of the biography and its relationship to poststructuralism, which allows for an appreciation of the literary features of the book. He points to how the specificity of the content, language, a mode of narration in Grzebiałkowska\u27s book make it a full-fledged literary work itself. As such the book departs from a typical biographical scheme. Juxtaposing the book with poststructural ideas leads to the reconsideration of the role of the author in the process of shaping of a biographical narrative
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