696 research outputs found
sj-docx-1-mdm-10.1177_0272989X231168618 – Supplemental material for A Systematic Review of Methods to Incorporate External Evidence into Trial-Based Survival Extrapolations for Health Technology Assessment
No full textSupplemental material, sj-docx-1-mdm-10.1177_0272989X231168618 for A Systematic Review of Methods to Incorporate External Evidence into Trial-Based Survival Extrapolations for Health Technology Assessment by Ash Bullement, Matthew D. Stevenson, Gianluca Baio, Gemma E. Shields and Nicholas R. Latimer in Medical Decision Making</p
A General Public Study on Preferences and Welfare Impacts of Antimicrobial Resistance in the United Kingdom
Get PDFBackground: Antibiotics have led to considerable increases in life expectancy. However, over time, antimicrobial resistance (AMR) has accelerated and is now a significant global public health concern. Understanding societal preferences for the use of antibiotics as well as eliciting the willingness to pay (WTP) for future research is crucial. Objective: To investigate preferences for different strategies to optimize antibiotic use and to understand WTP for future research in AMR and antimicrobial drug development.Methods: A discrete-choice experiment (DCE) was administered to a sample of the United Kingdom general population. Respondents were asked to make nine choices, each offering three options—two hypothetical “doctor and antibiotics” and one “no doctor – no antibiotics”—defined by five attributes: treatment, days needed to recover, risk of bacterial infection that needs antibiotics, risk of common side effects, and risk of AMR by 2050. Data were analyzed using random parameters logit models. A double bounded contingent valuation was also included in the survey to explore WTP for policies to contain AMR.Results: Among the 2,579 respondents who completed the survey, 1,151 always selected “no doctor– no antibiotic” and 57 never varied their choices; therefore, 1,371 responses were used in the analysis. Risk of AMR by 2050 was the most important and the “treatment” was the least important attribute, although this was sensitive to a higher risk of bacterial infection. The aggregate annual WTP for containing AMR was approximately £8.35 billion (~£5-£10 billion).Conclusions: The AMR risk is relevant and important to the general public. The high WTP suggests that large investments in policies or interventions to combat AMR are justified
What does the word ‘Europe’ make you think of? Conceptualisations of Europe in a local context
No full textThe present article investigates the construction of the sense of belonging toward Europe in the public sphere, employing a case-study conducted in Italy. The author argues that different conceptualisations of Europe are related to diverse “uses” of the media, familiarity with international cultural resources and participation in the transnational public sphere and civil society. These variables affect the construction of Europeans' sense of belonging
Correction: Yagüe, P., et al. Goals and Challenges in Bacterial Phosphoproteomics. Int. J. Mol. Sci. 2019, 20, 5678
No full textThe authors wish to make the following corrections to this paper [1]:The author name “Gemma Fernánez-García” should be “Gemma Fernández-García” [...
Petrarca e Osberno di Gloucester
No full textSi presenta l'edizione commentata delle note autografe di Petrarca contenute nel Par. Lat. 7492, testimonianza della lettura e dell’utilizzo delle Derivationes di Osberno di Gloucester, altrimenti mai esplicitamente menzionate altrove da Petrarca (il titolo e l’autore rimasero a lungo ignoti). In esse Petrarca indica accordi e discordanze con le Derivationes di Uguccione da Pisa.It presents the annotated edition of Petrarch's autograph notes contained in Para Lat. 7492, evidence of reading and the use of Derivationes Osberno of Gloucester, otherwise never explicitly mentioned elsewhere by Petrarch (the title and the author remained unknown for a long time). In them Petrarca indicates agreements and disagreements with the Derivationes of Huguccio
Le opere storiche di Antonio Ivani da Sarzana
No full textSi forniscono alcune osservazioni e contributi al volume Antonio Ivani da Sarzana, 'Opere storiche' in cui sono pubblicate le principali opere storiche di questo illustre umanista, scrittore prolifico impegnato attivamente nella vita civile e politica del tempo. Interessanti spunti di riflessione offre la tradizione manoscritta, in particolare per la presenza di numerosi autografi rivisti dall’autore.We provide some comments and contributions to the volume Antonio Ivani from Sarzana, 'Historical works' which are published in major historical works of this illustrious humanist, prolific writer actively involved in civic and political life of the time. Offers interesting insights into the manuscript tradition, in particular the presence of numerous autographs revised by the author
R v Evans (Gemma) [2009] EWCA Crim 650, Court of Appeal
No full textEssential Cases: Criminal Law provides a bridge between course textbooks and key case judgments. This case document summarizes the facts and decision in R v Evans (Gemma) [2009] EWCA Crim 650, Court of Appeal. The document also included supporting commentary from author Jonathan Herring.</p
What is the role of an interdisciplinary researcher?
No full text© The Author 2007; all rights reserved.James A Smith and Gemma E Care
STRANIERO E DEVIANZA IN ITALIA
No full textIl lavoro esamina la “questione immigrazione”, che ha assunto in Italia rilevanza crescente soprattutto per l’insorgere di conflittualità, provocando spesso sentimenti di insicurezza e una falsa percezione dell’immigrato come deviante, anche per effetto della rappresentazione mediatica. L’autore si propone di disegnare, attraverso i dati statistici ufficiali dal 2001, un quadro quantitativo e qualitativo dell’immigrazione irregolare e clandestina, nonché della criminalità degli stranieri, alla luce dei mutamenti delle politiche migratorie europee e italiane.This paper examines the "immigration issue", which has taken in recent years increasing importance in Italy, especially for the uprising of social conflicts, often because of the feelings of insecurity and a false perception of immigrants as deviant, partly as a outcome of media representation. The author outlines, through the analysis of official statistics since 2001, the quantitative/qualitative scenario of irregular and illegal migration and aliens' criminality according to the changes of European and Italian politics of migration control
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