3,151 research outputs found
Combinatorial approaches to peptide receptors
No full textThis thesis contains the evaluation of molecular receptors for peptide carboxylates. Chapter 1 outlines the scope of the work, including recent developments in the host-guest chemistry of oligopeptide carboxylates, the combinatorial paradigm, sequencing methodologies, its application to the discovery of receptors and the nature of guests of interest studied. Chapter 2 describes the evolution of a novel method of determining a solid-phase linked peptide sequence. Limitations are discussed. The method is then successfully implemented in the synthesis of a library ‘pseudo-tweezer’ receptors for carboxylates and a library of authentic tweezer receptors, including the synthesis of appropriate carboxylate-binding motifs. Chapter 3 describes the use of the libraries synthesised in solid-phase screening experiments with oligopeptide guests of biological interest. Results of these experiments are discussed, leading to the identification of receptors. Resynthesis of these receptors in both solid-phase-linked and free form is detailed and evaluation of binding is made. Chapter 4 describes the synthesis and binding constant evaluation of a receptor for the oligopeptide of interest D-Ala-D-Ala, which had previously been identified by alternative combinatorial methods.</p
Ethnic identity, political identity and ethnic conflict: simulating the effect of congruence between the two identities on ethnic violence and conflict
No full textThis thesis outlines and presents an alternative hypothetical process to the emergence of ethnic conflict. Ethnic conflicts, rather than being dependent upon pre-existing 'ancient hatreds', are instead the result of a congruence between ethnic and political identity which grants individuals the ability to use ethnicity to identify and eliminate political threats. This hypothesis is formed by the examination of three case studies of ethnic conflict: Lebanon, Northern Ireland and Croatia. This hypothesis is then formalised and tested using an agent based simulation in which agent interactions are dependent upon ethnic and political identity and the congruence between the two. As predicted there was a strong positive correlation between how accurately ethnic identity reflected political identity and the level of ethnically motivated violence in the simulation, although the relationship was not linear. Furthermore the effect of a shift in congruence was found to be roughly comparable to the effect of initialising agents with a moderate level of pre-existing ethnic antagonism
Keynote: Jon Gertner
No full textThe symposium will start on the evening of April 16 with a keynote address by Jon Gertner. Jon is a journalist, historian, and feature writer for The New York Times Magazine
as well as the author of the NYTimes bestseller, The Idea Factory. His address will focus on the issue of intellectual property and the ethical questions around the huge amount of human-generated content that large language models use as they are developed
Jon Mirande eta ironia
No full textLa ironía es un elemento que ha ido siempre unido a la poesía, y especialmente a la poesía moderna.Tras un pequeño repaso a esta en diferentes épocas, se pasa a describir las tres diferentes ironías de Jon Mirande: la intelectual, la social y la filosófica. Todo ello acompañado de ejemplosIrony is an element that has always been united to poetry, and especially to modern poetry. After a small revision of irony in different eras, the author then describes the three different ironies of Jon Mirande: intellectual, social and philosophical irony. All this illustrated with example
SHEPHERD SCHOOL SYMPHONY ORCHESTRA LARRY RACHLEFF music director JON KIMURA PARKER, piano Friday, December 3, 2010 8:00 p.m. Stude Concert Hall
No full textPROGRAM: Prelude to Act III of Lohengrin / Richard Wagner -- Symphony in C / Igor Stravinsky -- Piano Concerto No. 2 in B-jlat Major, Op. 83 / Johannes Brahm
SHEPHERD SCHOOL SYMPHONY ORCHESTRA JON KIMURA PARKER, piano Friday, December 7, 2001 8:00 p.m. Stude Concert Hall
No full textPROGRAM: Introduction to "Khovantchina" / Modest Mussorgsky arr. Nikolai Rimsky-Korsakov -- Rhapsody on a Theme of Paganini, Op.43 / Sergei Rachmaninoff -- Symphonic Dances, Op.45 / Sergei Rachmaninof
SHEPHERD SCHOOL SYMPHONY ORCHESTRA Preview Concert !! LARRY RACHLEFF, Conductor, CHO-LIANG LIN, Violin JON KIMURA PARKER, Piano
No full textPROGRAM: Violin Concerto / Christopher Rouse -- Rhapsody on a Theme of Paganini, Op. 43 / Sergei Rachmaninoff -- Concerto for Orchestra / Bela BartokNo printed program is available for this performance
Jon Pineda, 32nd Annual ODU Literary Festival
No full textJon Pineda is the author of The Translator\u27s Diary, winner of the Green Rose Prize for Poetry, and BIrthmark, winner of the Crab Orchard Award Series in Poetry Open Competition. His memoir, Sleep in Me, is forthcoming in 2010 from the University of Nebraska Press. He teaches in the low-residency MFA program at Queens University of Charlotte
FACULTY RECITAL, JON KIMURA PARKER, piano Wednesday, January 25, 2012 8:00 p.m. Lillian H. Duncan Recital Hall
No full textPROGRAM: Piano Sonata No. 3 in A minor, Op. 28 "D'apres des vieux cahiers" / Sergei Prokofiev -- Petrouchka / Igor Stravinsky, arr. Jon Kimura Parker -- Prelude in G minor, Op. 23 No. 5 / Sergei Rachmaninoff -- Pictures at an Exhibition / Modest Mussorgsky -- Prelude in G Major, Op. 32 No. 5 / Sergei RachmaninoffNo printed program is available for this performance
Interview with Jon Baskin--May 15, 2015
No full textJon Baskin is co-founder and editor of The Point magazine in Chicago. He is also a graduate student at the University of Chicago's Committee on Social Thought and the author of many essays and works of criticism for venues such as The Los Angeles Review of Books, The Nation, n+1, The New York Observer, BookForum, Salon, and The Point. Earlier in his career he was a fact checker for various magazines, including Popular Science, Inc Magazine, The Atlantic Monthly, and n+1. The interview was conducted at the office of The Point in Chicago on May 15, 2015.1_izzia9z
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