266,738 research outputs found
SHEER hos bondböna - dess molekylära funktion och potentiella roll i stresstolerans
Vicia faba, faba bean, is an ancient crop, which has seen a resurgence in popularity in Finland in recent years. Faba bean has a high protein content, high yield and positive effects on soil nutrients and pollinator communities, but is attacked by several pathogens, of which Botrytis spp. is the most damaging, sometimes destroying the whole yield. A lack of reference genome has slowed down breeding efforts, although this was solved last year with the publication of a faba bean reference genome. The Stress induced HEmE Receptor (SHEER) family of proteins have been shown to play a role in several cellular processes of animals and plants. SHEER is one of these proteins, having been shown to bind heme, be involved in stress resistance and pathogen resistance and possibly autophagy in the model organism Arabidopsis thaliana. The observations of the protein function in A. thaliana makes it an interesting target for research also in faba bean, a species in which SHEER has not yet been studied. SHEER is highly conserved in eukaryotes and can therefore be expected to have similar functional roles in A. thaliana and faba bean.
In this thesis, SHEER from the cultivars ‘Disco’ and ‘Tiffany’ is isolated and sequenced to determine the genomic and coding sequence of the gene. The heme binding ability of recombinant SHEER in vitro is demonstrated and the ability of the predicted heme binding and C-terminal domain of faba bean SHEER is shown to functionally complement sheer knockout A. thaliana plants. Furthermore, a phylogenetic tree was made of SHEER family homologs from 22 eukaryotic species, showing a split early in eukaryotic development between the SHEER homologs and the rest of the SHEER family homologs. The results presented in this thesis provide a good foundation for understanding SHEER function in faba bean, but more research is needed to determine further molecular functions, besides heme binding, and the role of the protein in physiological processes, such as pathogen resistance.Vicia faba, bondböna, är en antik gröda som har sett ett uppsving i popularitet i Finland under de senaste åren. Bondböna innehåller en hög andel protein, ger en stor skörd och har positiva effekter för pollinerare och på jordmånens ämnessammansättning. Bondböna drabbas dock av flertalet sjukdomar, varav chokladfläcksjuka orsakad av Botrytis spp. är den mest skadliga. Denna sjukdom kan till och med förstöra hela skörden på en åker. Bristen på ett referensgenom hos bondböna har försvårat förädlingen, vilket löstes förra året av att ett referensgenom för bondböna publicerades. Stress induced HEmE Receptor (SHEER) familjen av proteiner har visats spela en roll i flertalet cellulära processer hos både djur och växter. SHEER är ett av dessa proteiner och har visats binda hem, vara involverat i stresstolerans och patogenresistens, och möjligtvis vara involverat i autofagi i modellorganismen Arabidopsis thaliana. Observationerna av dessa funktioner i A. thaliana gör SHEER till ett intressant mål för forskning även i bondböna, en art där SHEER inte har undersökts tidigare.
I denna avhandling isolerar och sekvenserar jag SHEER från bondbönekultivaren ’Disco’ och ’Tiffany’ för att avgöra genens sekvens. Jag demonstrerar SHEERs förmåga att binda hem in vitro, och förmågan hos bondbönans SHEERs hembindande och C-terminala domäner att funktionellt komplettera sheer knockout A. thaliana jämförbart med vildtyp påvisas. Dessutom konstruerar jag ett fylogram med homologer till SHEER-proteinerna från 22 eukaryota arter, vilket indikerar en splittring av SHEER-homologerna från resten av SHEER-proteinernas homologer tidigt i eukaryoternas evolution. Resultaten som presenteras i denna avhandling utgör en lovande grund för att förstå funktionen av SHEER i bondböna. Mera forskning behövs dock inom detta område för att upptäcka ytterligare molekylära funktioner, förutom bindning av hem, hos SHEER och proteinets roll i fysiologiska processer, såsom patogenresistens, hos bondböna
Sistema Cucina "Sheer"
Sheer è una cucina a scomparsa brevettata prodotta da Sheer, marchio di Gatto cucine. Sheer è uno dei prodotti più innovativi apparsi negli ultimi anni nel settore delle cucine, per la bellezza della forma, per le soluzioni tecnologiche adottate, per i materiali avanzati utilizzati. Il suo successo è testimoniato dalle numerosissime recensioni ed esposizioni nelle più importanti mostre mondiali.
Sheer è costituita da un’isola circolare e da un mobile-parete. L’isola è composta da due semisfere di 148 cm. di diametro, che possono assumere la doppia configurazione aperta e chiusa. Quella inferiore è in carbonio o in acciaio. Quella superiore è in metacrilato traslucido con funzione di cappa aspirante e lampadario. Il mobile- parete autoportante, progettato nelle tre misure 180, 210 e 240 cm, rivestito in carbonio o in legno, è composto da un sistema espositivo con mensole-maniglie in alluminio, integrato ad un blocco posteriore per elettrodomestici ad inserimento laterale e cassettoni di contenimento. Si chiude con una tenda a rullo elettrificata
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
The erasure of race and racism
With the advent in the UK of a new Labour government in 1997 and the publication of the Macpherson report in 1999, public debate over race and racism was reactivated after a long period when such concerns had remained dormant. In this article, I shall draw upon an ethnographic study of one university in the UK over a ten year period (Pilkington, 2011a). Here I shall focus on the early part of that period, predominantly 1999-2003 when arguably issues relating to race and racism were at their height. I examine how Midshire University responded in turn to the Commission for Racial Equality’s (CRE’s) leadership challenge; the government’s strategies for higher education relating to widening participation and equal opportunities; and the race relations legislation. The story is not a happy one, with the institution constantly subsuming race under a more general agenda and in the process failing to address the specificities of race. Midshire University is unlikely to be the only university to do this. For universities in the UK are typically characterised by the ‘sheer weight of whiteness’ which blinds senior managers and academics to racial inequalities in their midst
Student Struggle for Soviet Jewry, with Rabbi Charles Sheer
Recording of a weekly radio program by Jerry Goodman
called "Russia Reports" that aired on the radio station WEVD. Rabbi
Charles Sheer, Jewish Chaplain at Columbia University, member of the
board of The Student Struggle for Soviet Jewry talks about the
beginnings, the functions and the methods of the SSSJ.Digital recordingDigital finding aid
Theōn hemerai: astrology, the planetary week, and the cult of the seven planets in the Graeco-Roman world
Protecting Animals 36: Author Witi Ihimaera
In this very special episode of Knowing Animals I am joined by beloved New Zealand author Witi Ihimaera. Witi has written many books featuring nonhuman animals. He offers us a non-colonial lens through which to think about the human/nonhuman relationship
Author Under Sail The Imagination of Jack London, 1893-1902
In Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Sheer Being and Thought
I wrote earlier on the difference between the Pippinian and Houlgatian interpretations of Hegel’s Logic. In the current piece, I want to elaborate a bit more on Stephen Houlgate’s take on what he calls ‘sheer being’. It will still be extremely exploratory, without delving into the detail of Hegel’s own text, let alone into the secondary literature on the beginning of the Logic (apart from Houlgate, important work in this area is offered by Robert Pippin, Dieter Henrich, Rolf-Peter Horstmann, and more recently Pirmin Stekeler-Weithofer in his massive 3-volume commentary on the Logic). The piece is chiefly critical of a particular, sophisticated and influential reading of the Logic, and doesn’t make propositions on how a positive reading of the Logic might look like.
These are just some more critical reflections on what I take to be an ultimately unsuccessful way of approaching Hegel’s Logic, one though that seems very influential and intuitively plausible. I am increasingly suspicious of their attempts to defend ontological readings of Hegel’s Being Logic, such as we can find in the work of Houlgate (but also many others). Below I shall comment in turn on various passages I quote from a recent essay by Houlgate (Houlgate 2018) and elaborate on some of the central arguments
“Dichotomies in Silk: Sheer and Opaque”
Since my days as a student of design, I was interested in fiber as a means to express myself creatively, influenced largely by Junichi Arai’s innovative works in the 1980s. As an artist, I emphasize the material itself and how it takes on shape in the same manner as that of a sculptor. It is in my character as an artist and designer to play with diverse materials and experiment with an array of techniques that can be applied to them. Illustrated by slides, I would like to share my creative exploration using silk fabric and recent technical improvements in surface design processes.
Having had the opportunity to explore a huge array of polyester fabrics in the 1990s, I experimented with the thermoplastic characteristics of polyester using various shaping processes and heat. This gave me the foundation to open the potential of silk when I later worked with Isao Negishi, a chemical engineer who perfected the process of silk cloque in combination with traditional Japanese paste-resist dying techniques of kata-zome (stenciled) and tsutsu-gaki (hand painted).
Sheer silk fabric may be either screen printed or hand-painted with paste-resist, then immersed in chemicals. This causes the exposed areas to crimp and condense into opaque sections, puckering the fabric. The resulting design is much like a bas-relief pattern set against the reserved areas of the original sheer fabric. A stronger chemical solution (or thinner reserve paste) yields greater shrinkage. The possibilities in achieving expressive textural patterns are endless and silk fiber, being natural, behaves like a living entity with its subtle nuances seen in each piece
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