155,838 research outputs found
Pioneer personal history, Mrs. Evelyn Sharp Taylor
No full textTypescript of a sketch biography of Evelyn (Sharp) Taylor of Portland, Oregon, from an interview in the 1930s when she was visiting Ogden. She was born in Plain City, Weber County, Utah, and her parents were Mormon pioneers who came to Utah in the 1850s. Typed by Maurice L.. Howe of Ogde
Physiological sharp wave-ripples and interictal events in vitro: What’s the difference?
No full textSharp wave-ripples and interictal events are physiological and pathological forms of transient high activity
in the hippocampus with similar features. Sharp wave-ripples have been shown to be essential in memory
consolidation, while epileptiform (interictal) events are thought to be damaging. It is essential to grasp the
difference between physiological sharp wave-ripples and pathological interictal events in order to
understand the failure of control mechanisms in the latter case. We investigated the dynamics of activity
generated intrinsically in the CA3 region of the mouse hippocampus in vitro, using four different types of
intervention to induce epiletiform activity. As a result, sharp wave-ripples spontaneously occurring in CA3
disappeared, and following an asynchronous transitory phase, activity reorganized into a new form of
pathological synchrony. During epileptiform events, all neurons increased their firing rate compared to sharp
wave-ripples. Different cell types showed complementary firing: parvalbumin-positive basket cells and
some axo-axonic cells stopped firing due to a depolarization block at the climax of the events in high
potassium, 4-aminopyridine and zero magnesium models, but not in the gabazine model. In contrast,
pyramidal cells started firing maximally at this stage. To understand the underlying mechanism we
measured changes of intrinsic neuronal and transmission parameters in the high potassium model. We found
that the cellular excitability increased and excitatory transmission was enhanced, whereas inhibitory
transmission was compromised. We observed a strong short-term depression in parvalbumin-positive basket
cell to pyramidal cell transmission. Thus, the collapse of pyramidal cell perisomatic inhibition appears to be
a crucial factor in the emergence of epileptiform events
Personal Papers (MS 80-0002)
No full textLetter from Harris L. Kempner to Tina and Dudley Sharp, expressing his excitement at their joining the Philosophical Society of Texas
The sharp A(p) constant for weights in a reverse-Holder class
No full textCoifman and Fefferman established that the class of Muckenhoupt weights is equivalent to the class of weights satisfying the "reverse Holder inequality". In a recent paper V. Vasyunin [17] presented a proof of the reverse Holder inequality with sharp constants for the weights satisfying the usual Muckenhoupt condition. In this paper we present the inverse, that is, we use the Bellman function technique to find the sharp A(p) constants for weights in a reverse-Holder class on an interval; we also find the sharp constants for the higher-integrability result of Gehring [7].Additionally, we find sharp bounds for the A(p) constants of reverse-Holder-class weights defined on rectangles in R-n, as well as bounds on the A(p) constants for reverse-Holder weights defined on cubes in R-n, without claiming the sharpness.</p
Letter from Ed. Sharp & Sons to L. De Bona.
No full textLeonard de Bona was a businessman, possibly of Italian descent, in Eagle Pass, Texas, who ran a hardware and supply store in that area for nearly 20 years. He served as a point of contact for customers throughout South Texas and nearby Mexico, providing not only hardware but food, clothing, and sundries. He had business contacts in San Antonio, Chicago, and abroad (Central Mexico, Italy, and other locations.)Archive of Correspondence relating to L. de Bona's Eagle Pass Hardware and Supply Store from 1887-1903 and undated. Approximately 500 letters, varying states of condition, some browning. An important archive for a businessman on the border in Eagle Pass, Texas with nearly 500 letters, most from neighboring Texas communities, order supplies.Organized by the following series: Correspondence and ChronologicalBona, L. de, Papers, 1887-1903 and undated, Southwest Collection/Special Collections Library, Texas Tech University, Lubbock, TexasEd. Sharp & Sons - General Commission Merchants - Retail Grocers - Shippers and Dealers in Fruits and Fruit-growers' Supplies
Sharp de Rham realization
No full textWe introduce the sharp (universal) extension of a 1-motive (with additive factors and torsion) over a field of characteristic zero. We define the sharp de Rham realization by passing to the Lie-algebra. Over the
complex numbers we then show a (sharp de Rham) comparison theorem in the category of formal Hodge structures. For a free 1-motive along with its Cartier dual we get a canonical connection on their sharp extensions yielding a perfect pairing on sharp realizations. Thus we show how to provide one-dimensional sharp de Rham cohomology of algebraic varieties
ON SHARP CHARACTERS OF TYPE {l, l + p}
No full textFor a character χ of a finite group G, it is known that the product sh(χ) = Π_<l∈L>(χ(1) − l) is a multiple of |G|, where L is the image of χ on G − {1}. χ is said to be a sharp character of type L if sh(χ) = |G|. This is a generalization of the permutation characters of sharp permutation groups. Without loss of generality, we may assume that (χ, 1_G)_G = 0. In this paper, we classify the finite groups with sharp characters of type {l, l + p} for an odd prime p under the additional hypothesis Z(G) > 1 and (χ, χ)_G = p
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