1,172 research outputs found
The clinical utility of microarray technologies applied to prenatal cytogenetics in the presence of a normal conventional karyotype: a review of the literature
No full textThe clinical utility of microarray technologies when used in the context of prenatal diagnosis lies in the technology's ability to detect submicroscopic copy number changes that are associated with clinically significant outcomes. We have carried out a systematic review of the literature to calculate the utility of prenatal microarrays in the presence of a normal conventional karyotype. Amongst 12?362 cases in studies that recruited cases from all prenatal ascertainment groups, 295/12?362 (2.4%) overall were reported to have copy number changes with associated clinical significance (pCNC), 201/3090 (6.5%) when ascertained with an abnormal ultrasound, 50/5108 (1.0%) when ascertained because of increased maternal age and 44/4164 (1.1%) for all other ascertainment groups (e.g. parental anxiety and abnormal serum screening result). When additional prenatal microarray studies are included in which ascertainment was restricted to fetuses with abnormal ultrasound scans, 262/3730 (7.0%) were reported to have pCNCs
Chromosome Abnormalities and Genetic Counseling
No full text4th ed.This third edition has been thorougly updated, and is richly illustrated and fully referenced. New chapters have been written on preimplantation diagnosis and on reproductive risks due to environmental agents.Edited by R.J. McKinlay Gardner, Grant R. Sutherland, Lisa G. Shafferhttp://nla.gov.au/anbd.bib-an4671493
Being on the mat: Quasi-sacred spaces, ‘exotic’ other places, and yoga studios in the ‘West’
No full textThe chapter, "Being on the mat: Quasi-sacred spaces, ‘exotic’ other places, and yoga studios in the ‘West’" was written by Lisa Smith (Douglas College Faculty). Book description: This volume considers the phenomenon of yoga travel as an instance of a broader genre of ‘spiritual travel’ involving journeys to places ‘elsewhere’, which are imagined to offer the possibility of profound personal transformation. These imaginings are tied up in a continued exoticization of the East, but they are not limited to that. Contributors identify various themes such as authenticity, suffering, space, material markers, and the idea of the ‘spiritual’, tracing how these ideas manifest in conceptions and fetishizations of ‘elsewhere.’ To deepen its analysis of this phenomenon, the book incorporates a wide range of disciplines including architecture, sociology, anthropology, philosophy, women’s studies, religious studies, and history. While the book’s primary focus is yoga and yoga travel, contributors offer up an array of other case studies. Chapters delve into the complex questions of agency and authenticity that accompany the concept of ‘spiritual travel’ and ideas of ‘elsewhere.’
Chapter abstract: While most Westerners might not be able to provide an in-depth explanation of what exactly it is, yoga is a familiar word, even if it looks significantly different from practices that one might find in India. This chapter draws on a mini ethnography of two yoga studios in Montreal in order to better understand and examine yoga in the ‘West’. The author argues that yoga studios can reveal some of the particularities of self-formation in the West as it relates to the construction of the spiritual and religious subject. Most contemporary yoga studios house all manner of religious and spiritual objects that refer to exotic other places; indeed, it is this connection to ‘other’ places that lends the studio its legitimacy as a sacred space.book chapterPublished.Religious and spiritual objectsEthnography of yoga studiosYoga and self-formation in the 'West
Data for: NanoFlow Sheath Voltage Free Interfacing of Capillary Electrophoresis and Mass Spectrometry
No full textThese data are related to the following publication:Yousef S. Elshamy, Timothy G. Strein, Lisa A. Holland, Chong Li, Anthony DeBastiani, Stephen J. Valentine, Peng Li, John A. Lucas, Tyler A. Shaffer, NANOFLOW SHEATH VOLTAGE-FREE INTERFACING OF CAPILLARY ELECTROPHORESIS AND MASS SPECTROMETRY FOR THE DETECTION OF SMALL MOLECULES. Analytical ChemistryTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOV
Toxicological profile for toluene diisocyanate and methylenediphenyl diisocyanate
No full textA Toxicological Profile for Toluene Diisocyanate and Methylenediphenyl Diisocyanate, Draft for Public Comment was released in September 2015. This edition supersedes any previously released draft or final profile.Chemical manager(s)/author(s): Malcolm Williams, G. Daniel Todd, Hana R. Pohl, Jessilynn Taylor, ATSDR, Division of Toxicology and Human Health Sciences, Atlanta, GA; Lisa Ingerman, Heather Carlson-Lynch, Courtney Hard, Mario Citra, SRC, Inc., North Syracuse, NY.tp206.pdf201810.15620/cdc5808
Addiction recovery stories: Bradley Maguire in conversation with Lisa Ogilvie
No full textPurpose: The purpose of this paper is to examine recovery through lived experience. It is part of a series that explores candid accounts of addiction and recovery to identify important components in the recovery process. Design/methodology/approach: The G-CHIME model comprises six elements important to addiction recovery (growth, connectedness, hope, identity, meaning in life and empowerment). It provides a standard against which to consider addiction recovery, having been used in this series, as well as in the design of interventions that improve well-being and strengthen recovery. In this paper, a first-hand account is presented, followed by a semi-structured e-interview with the author of the account. Narrative analysis is used to explore the account and interview through the G-CHIME model. Findings: This paper shows that addiction recovery is a remarkable process that can be effectively explained using the G-CHIME model. The significance of each component in the model is apparent from the account and e-interview presented. Originality/value: Each account of recovery in this series is unique and, as yet, untold
Addiction recovery stories: Rebecca Kippax in conversation with Lisa Ogilvie
No full textPurpose: The purpose of this paper is to examine recovery through lived experience. It is part of a series that explores candid accounts of addiction and recovery to identify the important components in the recovery process. Design/methodology/approach: The G-CHIME model comprises six elements important to addiction recovery (Growth, Connectedness, Hope, Identity, Meaning in life and Empowerment). It provides a standard against which to consider addiction recovery, having been used in this series, as well as in the design of interventions that improve well-being and strengthen recovery. In this paper, a first-hand account is presented, followed by a semi-structured e-interview with the author of the account. Narrative analysis is used to explore the account and interview through the G-CHIME model. Findings: This paper shows that addiction recovery is a remarkable process that can be effectively explained using the G-CHIME model. The significance of each component in the model is apparent from the account and e-interview presented. Originality/value: To the best of the authors' knowledge, each account of recovery in this series is unique, and as yet, untold
Addiction recovery stories: Lauren Wearing in conversation with Lisa Ogilvie
No full textPurpose: This purpose of this paper is to contribute to a series of recovery stories that examine candid accounts of addiction and recovery. Shared components in the recovery process are considered, along with the change and growth needed to support the transition from addiction to recovery. Design/methodology/approach: The connectedness, hope, identity, meaning in life and empowerment (CHIME) framework comprises five elements important to recovery. CHIME provides a standard to qualitatively study recovery. As a model, it has been extended to include growth (G-CHIME), an element that is important for sustained addiction recovery. In this paper a first-hand account of addiction recovery is presented, followed by a semi-structured e-interview with the author of the account that is based on the G-CHIME model. Findings: This paper shows that addiction recovery is a remarkable process that can be effectually explained using the G-CHIME model. The significance of each element in the model is apparent from the biography and e-interview presented. Originality/value: Each account of recovery in this series is unique, and as yet, untold
Addiction recovery stories: Bethany Holmes in conversation with Lisa Ogilvie
No full textPurpose: The purpose of this paper is to examine recovery through lived experience. It is part of a series that explores candid accounts of addiction and recovery to identify important components in the recovery process. Design/methodology/approach: The G-CHIME model comprises six elements important to addiction recovery (growth, connectedness, hope, identity, meaning in life and empowerment). It provides a standard to against which to consider addiction recovery, having been used in this series, as well as in the design of interventions that improve well-being and strengthen recovery. In this paper, a first-hand account is presented, followed by a semi-structured e-interview with the author of the account. Narrative analysis is used to explore the account and interview through the G-CHIME model. Findings: This paper shows that addiction recovery is a remarkable process that can be effectively explained using the G-CHIME model. The significance of each component in the model is apparent from the account and e-interview presented. Originality/value: Each account of recovery in this series is unique, and as yet, untold
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