1,720,953 research outputs found

    Subacute thyroiditis: Fine-needle aspiration cytology of 14 cases presenting with thyroid nodules

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    Subacute thyroiditis (SAT) is usually diagnosed clinically without the need for fine-needle aspiration. The cytologic literature on this condition is therefore rare. We report on 14 cases of SAT presenting with thyroid nodules. The majority of patients were women with a mean age of 46 yr. All had pain-tenderness in the thyroid area accompanied by fever or an elevated ESR. The salient cytologic features included cellular smears; multi-nucleated giant cells in 100percent of cases, some ingesting colloid or neutrophils; fibrous fragments with enmeshed inflammatory cells were a constant feature; follicular cells were scant to absent in most cases. Granulomas were rare. Colloid, when present was thick, with central cracks and frayed edges. One case was suspicious for malignancy. We conclude that the cytologic features of SAT are predictable, particularly, in the appropriate clinical setting. FNA is also helpful in ruling out concomitant neoplastic conditions. © 2005 Wiley-Liss, Inc.Coup A, 1997, CYTOPATHOLOGY, V8, P218; DAVIDSON HG, 1991, COMPREHENSIVE CYTOPA, P650; de Pauw B E, 1975, Neth J Med, V18, P70; EYLAN E, 1957, LANCET, V1, P1063; GREENE JN, 1971, AM J MED, V51, P97, DOI 10.1016-0002-9343(71)90327-5; GUARDA LA, 1987, AM J CLIN PATHOL, V87, P14; HAZARD JB, 1955, AM J CLIN PATHOL, V25, P289; JAYARAM G, 1987, ACTA CYTOL, V31, P687; KLINE TS, 1981, HDB FINE NEEDLE ASPI; KOSS LG, 1984, ASPIRATION BIOPSY CY; LARSEN PR, 1974, METABOLISM, V23, P467, DOI 10.1016-0026-0495(74)90094-8; LINDSAY S, 1954, SURG GYNECOL OBSTET, V98, P197; LIVOLSI VA, 1990, SURGICAL PATHOLOGY T, P367; Lu CP, 1997, ACTA CYTOL, V41, P238; MARTINO E, 1987, J ENDOCRINOL INVEST, V10, P321; MEACHIM G, 1963, J CLIN PATHOL, V16, P189, DOI 10.1136-jcp.16.3.189; OFNER C, 1994, CYTOPATHOLOGY, V5, P33, DOI 10.1111-j.1365-2303.1994.tb00125.x; PERSSON PS, 1968, ACTA MED SCAND S, V483, P8; Shabb NS, 1999, DIAGN CYTOPATHOL, V21, P307, DOI 10.1002-(SICI)1097-0339(199911)21:5307::AID-DC23.0.CO;2-1; SOLANO JG, 1997, DIAGN CYTOPATHOL, V3, P214; SWANN NH, 1964, METABOLISM, V13, P908, DOI 10.1016-0026-0495(64)90080-0; VOLPE R, 1978, HUM PATHOL, V9, P429, DOI 10.1016-S0046-8177(78)80028-8; VOLPE R, 1979, CLIN ENDOCRINOL META, V8, P81, DOI 10.1016-S0300-595X(79)80011-0; WOOLF PD, 1985, MED CLIN N AM, V69, P1035; WOOLNER LB, 1957, J CLIN ENDOCR METAB, V17, P120212131

    Indeterminate and Erroneous Fine-Needle Aspirates of Breast with Focus on the 'True Gray Zone': A Review

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    Objective: To review our experience and the literature on inconclusive-erroneous fine-needle aspirates (FNAs) of breast with the focus on the 'true gray zone'. To describe the cytology, differential diagnosis, pitfalls and limitations of common and rare lesions. Study Design: We conducted a literature search focusing on breast FNAs with statistical data of C3 and C4 categories including false-positive and false-negative cases. Similar data from 2003 to 2009 was obtained from our institution. Results: C3 and C4 categories account for 3-17percent of breast FNAs. Contributing factors are technical difficulties, inexperienced pathologists interpreting FNAs of breast and overlap of cytologic features of certain benign and malignant conditions; this last, 'true gray zone' accounts for 2percent of cases. Fibroadenoma, proliferative breast lesions, gynecomastia, infiltrating and in situ low-grade adenocarcinomas and tubular, cribriform, lobular and mucinous carcinomas are the most common problematic lesions. Granular cell tumor, adenomyoepithelioma, pregnancy-related lesions, fat necrosis, inflammatory and radiation changes, adenoid cystic carcinoma, spindle-cell lesions and Phyllodes tumor are less common. Conclusion: Inconclusive-erroneous FNAs of breast due to the 'true gray zone' are rare. Most are due to the overlapping cytologic features of some benign and malignant conditions. Practical features that may help arrive at the correct diagnoses are elucidated. Copyright © 2013 S. 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    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    AIRP best cases in radiologic-pathologic correlation: Alveolar soft-part sarcoma

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    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    Atorvastatin-induced severe gastric ulceration: A case report

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    A 41-year-old man presented with severe gastric ulceration 3 mo after beginning treatment with atorvastatin 20 mg once daily for hypercholesterolemia. The patient was not taking any ulcerogenic drugs and had no evidence of Helicobacter pylori infection. Proton pump inhibitor therapy was initiated and atorvastatin was replaced by simvastatin with complete resolution of gastrointestinal symptoms. To our knowledge, this is the first report of atorvastatin-induced gastric ulceration, which should be looked for in patients who develop abdominal pain while on this drug. © 2005 The WJG Press and Elsevier Inc. All rights reserved.Adcock B B, 2001, J Am Board Fam Pract, V14, P148; Andrejak M, 2003, THERAPIE, V58, P77, DOI 10.2515-therapie:2003011; Anliker MD, 2002, ALLERGY, V57, P366, DOI 10.1034-j.1398-9995.2002.1n3628.x; Belaiche G, 2000, GASTROEN CLIN BIOL, V24, P471; Chazerain P, 2001, JOINT BONE SPINE, V68, P430, DOI 10.1016-S1297-319X(01)00300-1; Gonzalez-Ponte ML, 1998, LANCET, V352, P1284, DOI 10.1016-S0140-6736(05)70491-8; Jimenez-Alonso J, 1999, ARCH INTERN MED, V159, P1811, DOI 10.1001-archinte.159.15.1811-a; LACY C, 2001, DRUG INFORM HDB, P109; Malinowski JM, 1998, AM J HEALTH-SYST PH, V55, P2253; Nakad A, 1999, LANCET, V353, P1763, DOI 10.1016-S0140-6736(99)00569-3; Negevesky G J, 2000, Arch Ophthalmol, V118, P427; Noel B, 2001, AM J MED, V110, P670, DOI 10.1016-S0002-9343(01)00711-2; Pfeiffer CM, 1998, JAMA-J AM MED ASSOC, V279, P1613, DOI 10.1001-jama.279.20.1613-a; Segal AS, 2002, AM J MED, V113, P171, DOI 10.1016-S0002-9343(02)01135-X; Sinzinger H, 2002, WIEN KLIN WOCHENSCHR, V114, P943; Sulem P, 2001, ANN PHARMACOTHER, V35, P1292; Ziajka PE, 1998, SOUTHERN MED J, V91, P66774
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