11,194 research outputs found
Teaching About Magnetism
No full textThis web page, created by author David P. Stern, are the lecture notes for a presentation to middle and high school teachers to help teach magnetism. The lectures includes a brief history of the study of magnetism from its beginnings in ancient Greece and China to the present day, and three classroom demonstrations. This is part of a larger web site on "The Earth's Magnetosphere." Additionally, the author provides links to a glossary and expanded timeline to help better contextualize the theories addressed in these lecture notes
Newton's Laws
No full textAuthored and curated by David P. Stern, this series of web pages, part of "From Stargazers to Starships," describes Newton's three laws of motion and the two concepts on which they are based, force and inertia. The author breaks down the page in this fashion: the concept of force, motion against outside resistance, and motion with significant resistance. The author also provides additional links for further study on the life of Issac Newton. A lesson plan for instructors is also provided
Flight to Mars
No full textCreated by David P. Stern, this set of three web pages provides a calculation of paths, times, and distances for a flight to Mars and back. The author uses a Hohmann transfer ellipse between two circular orbits. This is an example and application of Kepler's Laws, which are explained in related web pages. Only algebra is used with Kepler's laws and the equation for the energy of Kepler motion. This is part of an extensive work, "From Stargazers to Stars that uses space science as an introduction to basic physics principles. Also available in French
Discovery of the Magnetic Compass
No full textFirst of several linked files, telling the early history of the compass (discovered in China) and how Robert Norman in 1581 showed the magnetic force was not horizontal but slanted downwards, followed by William Gilbert's demonstration that the Earth behaved like a giant magnet; two reviews of Gilbert's 1600 book "De Magnete" follow, as well as a modern version of one of Gilbert's experiments. The web collection also includes several sections for science teachers. The page is a subset of a larger collection of articles of the history of magnetism created by author David P. Stern
E-book : Industrial Transformation In The Developing World (author: Michael T. Rock & David P. Angel)
No full textArsip Kuliah Online 2010: E-book : Industrial Transformation In The Developing World (author: Michael T. Rock & David P. Angel
E-book : "industrial Transformations In The Developing World (author: Michael T. Rock & David. P Angel)
No full textArsip Kuliah Online 2010: E-book : "industrial Transformations In The Developing World (author: Michael T. Rock & David. P Angel
Cult: A Composite Novel
No full textCult (redacted)
The first component of the thesis is a composite novel called Cult which falls into two parts with seven narratives in each. Part 1 tracks the protagonist, Ellen, from her first involvement with the cult through to her eventually leaving it. Although fiction, the first half of the book answers the kinds of questions the author is asked when people discover that she was once a sannyasin (a follower of the guru Bhagwan Shree Rajneesh). While the experiences of meditation, group therapy and communal living are all faithfully rendered within the stories, the need for strong characters, narrative drive and a lightness of touch takes precedence.
Part 2 picks up Ellen’s story some twenty or so years later and explores what becomes of her in middle age. It also looks at other groups in society, such as academia, the law and the internet dating community which each have their own jargon, hierarchies, rituals and rules but are not considered to be cults.
The book examines the question raised in the Epigraph, ‘how do we be together when we feel so alone’ with a focus on relationships other than the familial and the romantic.
Collisions, Chasms and Connections: a Performative Exploration of the Composite Novel Form
The second part of the thesis is both a critical and creative response to three contemporary American books: Olive Kitteridge by Elizabeth Strout; A Visit from the Goon Squad by Jennifer Egan; and Legend of a Suicide by David Vann. The critical element comprises a close reading of the three books; a chronological reconstruction of their overarching storylines; and a consideration of what their authors have said about writing the books. It concludes that, in the composite novel, the simultaneous presentation of multiple views and storylines operate much like a 3D image to give the impression of depth to the characters and situations rendered. The creative element of the essay is a playful and personal response to the texts
Interview with David P. Twomey on forty-six years of publishing and teaching at Boston College
No full textProfessor David Twomey researches and publishes in the area of labor and employment law. His research and publication interests also extend to contract law, intellectual property rights, business organizations, corporate governance, franchising and international business transactions. He is the author of some thirty-four editions of widely used textbooks on labor, employment and business law topics. His articles have appeared in journals such as Best's Review, The Labor Law Journal, The American Business Law Journal, The Massachusetts Law Quarterly, The Florida Bar Journal, and The Business Law Review. View some of his publications in the eScholarship@BC repository.Title supplied by cataloger
Role of macrophage colony stimulating factor-1 (CSF-1) in postnatal growth
No full textColony-Stimulating Factor (CSF-1) is required for the proliferation, differentiation
and survival of cells of the mononuclear phagocyte lineage. Mice with a mutation in
their CSF-1 gene demonstrate abnormal development in many organ systems and
severe growth retardation. These defects can be corrected by administration of rh-
CSF-1, and when similarly administered to wild-type mice, can increase organ and
body weight, thus highlighting the importance of CSF-1 in postnatal growth. CSF-1
is known to be elevated in the circulation in the immediate postnatal period of both
mice and humans. It remains to be seen whether CSF-1 deficiency underlies
important clinical issues such as low birth weight, and whether there are any
functionally important variations in expression or biology of CSF-1, or the
alternative CSF-1R ligand IL-34 that contributes to variation in somatic growth
between individuals. This thesis aimed to use the pig as a model for human innate
immunity and disease based upon recent publications that highlighted the similarities
in their immune systems.
To investigate the effects of CSF-1 on postnatal growth the first aim was to
characterise the CSF-1R system in pigs and produce reagents. Biologically active
porcine CSF-1 and IL-34 were produced along with expression of full length
functional porcine CSF-1R and production of anti-CSF-1R antibodies. A bioassay
was developed and optimised to assess the biological activity of these proteins. The
cross-species reactivity of a range of species CSF-1 and IL-34 proteins was
investigated in-vitro using the bioassay and cell culture systems. Recombinant CSF-1
is known to have a short half-life. Since conjugation of proteins to the Fc region of
immunoglobulins has been used extensively to improve circulating half-life; a
porcine Fc CSF-1 fusion protein was generated by commercial partners, Pfizer
Animal Health. The conjugated and un-conjugated CSF-1 proteins had identical
activity in cell line and primary cell assays in-vitro. The in-vivo activity of porcine
Fc CSF-1 was tested initially in the Csf1r-EGFP+ mouse reporter line and C57BL/6
mice. The Fc CSF-1 protein was more active than the native protein in promoting
increased monocyte and tissue macrophage numbers, increasing body weight and
inducing hepatosplenomegaly. Hepatic growth was associated with extensive
macrophage infiltration and hepatocyte proliferation, identified by gene expression
profiling as well as immunohistochemistry. Fc CSF-1 was then tested in neonatal
pigs. They were found to have an immature immune system that develops with age.
No postnatal surge of CSF-1 was detected. Fc CSF-1 administration increased blood
monocyte and neutrophil numbers confirming that CSF-1 is not saturating at this
time. Nevertheless, no influence on postnatal growth rate was identified. This is
discussed in terms of the differences in placental architecture in the pig compared to
human and mouse. This thesis demonstrates the effectiveness of porcine Fc CSF-1 in
both mice and porcine and highlights the important role that CSF-1 and macrophages
play in liver homeostasis. Fc CSF-1 is identified as candidate therapeutic agent in
humans and companion animals for tissue regeneration, and a tool for the study of
the role of macrophages in physiology and pathology
Senate Bill 1205 - Elaine Maimon Email to David Tierney
No full textThis email from ASU West Campus Provost Elaine Maimon to David Tierney discusses the passage of SB 1205 by the Arizona Senate and relates her concerns about the House Education Committee
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