177,268 research outputs found
Prevention of head and neck squamous cell carcinoma. Integrated treatment approach with diet, pharmaco-nutritional support, antioxidants, and cis-retinoic acid. Phase II study
No full text(0) Save to: more options IMPROVEMENT OF PHYSICAL ACTIVITY AS AN ALTERNATIVE OBJECTIVE VARIABLE TO MEASURE TREATMENT EFFECTS OF ANTI CACHEXIA THERAPY IN CANCER PATIENTS
No full textWe believe that presently, and even more so in the near future, the consistent application of objective, patient-centered endpoints in cachexia trials, such as physical activity monitoring, may provide an additional significant and useful tool for the evaluation of outcomes of medical interventions in cancer cachexia
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
MESNA (2-mercaptoethane sulfonate) is effective in inducing lymphocyte progression through cell cycle in patients with advanced cancer of different sites
No full textSubstrates to contrast compaction in urban tree plantings
No full textAim of our work was to assess the ability of recycled crushed bricks, employed as a substrate of growth, of contrasting the compaction and improving the development of trees in urban avenues. Soil employed in urban planting is often deep subsoil with a high percentage of fine material (silt and clay) and no organic matter. The soil compaction due to trampling and car parking can seriously affect the survival of trees in these conditions. Coarse recycled materials already used in urban green areas, allow a better air circulation and water drainage in the rizosphere and can be a valid solution to reduce the post transplant crisis. The materials employed as substrate were: compost, soil, crushed bricks 0-30 mm, crushed bricks 6-30 mm The experimental trial was set up planting 36 lindens in 1) soil, 2) soil +15 (v/v) compost; 3) crushed bricks 0-30 mm; 4) crushed bricks 0-30 mm + 15 compost; 5) crushed bricks 6-30 mm; 6) crushed bricks 6-30 mm + 15 compost. The monitoring included: sprouts length, number of sprouts, SPAD chlorophyll, and dynamic plate resistance. In the preliminary results the crushed bricks showed the highest resistance to compaction, and the combination of crushed bricks 0-30 mm + compost produced the average longest sprouts. At this stage of the research the best compromise between resistance to compaction and growth seems to be crushed bricks 6-30 mm + compost
Ross: Entre teoría y práctica del derecho. Una relectura crítica del Demokrati, magt og ret
No full textAlf Ross (1899-1979) is the most authoritative representative of xx’s century legal realism. From 1938, he held the chair of International Law at the University of Copenhagen, and later that of Philosophy of Law. From 1935 until 1977, he was appointed Secretary of the Chamber of Commerce. In 1953 he took part in the drafting of the Danish Constitution. Furthermore, from 1959 to 1972, Ross held the position of Judge of the European Court of Human Rights in Strasbourg. In Demokrati, magt og ret [Democracy, Power and Law], Alf Ross had selected and published some articles, previously released in various Danish newspapers over a period of about twenty years (from 1957 to 1974). The Italian translation of the Danish version (edited and introduced by Alessandro Serpe) is supplemented by two significant and more nourishing essays released some years before: “Kommunismen og Demokratiet” [“Communism and Democracy”] and “Socialismen och Demokratin” [“Socialism and Democracy”]. The former was published as a Danish brief monograph in 1945, while the latter, on the Swedish journal Tiden in 1947. In those essays, Ross reflects upon the concept of democracy, by comparing it with the concepts of Liberalism, Communism and Socialism. The articles contained in Demokrati, magt og ret reveal multiple further aspects of Ross’s thought – alongside those well-known within his legal-philosophy scholarship. From the viewpoints of chronicler and passionate political and social commentator, in these articles Ross makes evident his dedication to the practice of law, by dealing with then-actual matters falling into a wide spectrum of domains: from philosophy of law to criminal law, from international law, to political science and comparative law.Alf Ross (1899-1979) ha sido uno de los más insignes representantes del realismo jurídico del siglo XX. Desde 1938, ha cubierto la cátedra de Derecho Internacional en la Universidad de Copenhage y después, desde 1938 aquella de Filosofía del Derecho. Desde 1935 hasta 1977, ha tenido el cargo de secretario de la Cámara de Comercio. En 1953 contribuyó a la redacción de la Constitución danesa. Además, desde 1959 hasta 1972, ejerció la función de juez de la Corte Europea de los Derechos Humanos, en Estrasburgo. En el volumen Demokrati, magt og ret (Democracia, poder y derecho), Ross seleccionó y publicó algunos artículos precedentemente aparecidos en varias revistas danesas en un arco temporal de aproximadamente veinte años (desde 1957 hasta 1974). La traducción italiana de Alessandro Serpe de la versión danesa de la obra está integrada por dos ensayos con un apéndice: “Kommunismen og Demokratiet” [“Comunismo y democracia”] y “Socialismen och Demokratin” [“Socialismo y democracia”] publicados respectivamente, el primero con una breve monografía en lengua danesa en 1945 y el segundo en 1947, en la revista sueca Tiden. En estos ensayos Ross reflexiona sobre el concepto de democracia, comparándolo con aquel de liberalismo, comunismo y socialismo. Los artículos contenidos en Demokrati, magt og ret revelan aspectos múltiples y ulteriores del pensamiento de Ross, además de aquel de filósofo del derecho. Ampliamente conocido, desde la perspectiva de cronista y apasionado comentador social y político, Ross exhibe su empeño en la práctica del derecho, afrontando cuestiones prácticas que caen bajo un amplio espectro de dominios: de la filosofía del derecho al derecho penal, del derecho internacional, a la ciencia política y al derecho comparado
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Acoustic characterization of ultrasound fields able to induce sonodynamic activity in an in vitro cancer model
No full textThe corner stone of cancer management is by far chemotherapy, unfortunately toxicity and undesired side-effects of these antineoplastic approach often limit its usefulness. Recently it has been found that certain dye compounds non cytopathogenic per sé, in particular porphyrins, can achieve a cytopathogenic effect when the neoplastic site is subjected to ultrasounds irradiation, this technique is referred to as sonodynamic therapy (SDT). Despite the promising results, the poor reproducibility of the treatment, due to the poor investigation between the ultrasounds field parameters and the SDT activity, hampered the development of robust treatment protocol. Therefore the aim of this work has been the characterization of high intensity ultrasound fields needed to reach the SDT activity. First, by an ultrasound generator system, an in vitro sonodynamic treatment has been performed on HT-29 cell line, previously pre-incubated with 50 μg/mL of aminilevulinic acid, therefore a complete characterization of the ultrasound field in measurement conditions has been carried out. An ONDA type AIMS III scanning tank system with needle hydrophone ONDA type has been used and the real energy that hit the cellular culture in the burette has been evaluated. During insonation process the energy supplied to the cells has been about 5 10-6 J introducing, for the first time in the sonodynamic field, a clear parameter of energy supplied to the cells. © 2015 IEEE
Letter from R. R. Zellick, Assistant Trust Officer, Anglo California National Bank of San Francisco, to Joseph R. Goodman, October 2, 1942
No full textLetter from R. R. Zellick, Assistant Trust Officer at The Anglo California National Bank of San Francisco, to Joseph R. Goodman, regarding property owned by Dave Tatsuno. Zellick mentions a dispute between current tenants and Tatsuno, and that Tatsuno has asked Goodman to help locate trustworthy tenants.Personal correspondence, organizational records, government documents, publications, and other papers created or collected by Joseph R. Goodman documenting the forced removal and incarceration of Japanese Americans during World War II, as well as organized resistance to incarceration. Included in the collection are records of the Japanese Young Men's Christian Association and the Japanese American Citizens' League in San Francisco, including papers of the Japanese YMCA's executive secretary Lincoln Kanai; Sakai family papers; Goodman's correspondence to and from Japanese American incarcerees, organizations opposing forced removal and incarceration of Japanese Americans, the War Relocation Authority, and others; publications, photographs, and ephemera from the Topaz Relocation Center, where Goodman taught high school; War Relocation Authority records and publications; and newspaper clippings, pamphlets, and reports about forced removal and incarceration created by various government, religious, and civic organizations, in California and nationwide
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