1,721,062 research outputs found
[Follow-up and the specialist-patient relationship. Data of the observational UroLink study]. FT Il follow-up ed il rapporto specialista/paziente. Dati dello studio osservazionale Urolink.
No full text[Follow up and the specialist-patient relationship. Update]. FT Il follow-up ed il rapporto specialista/paziente. Update.
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
[Echography and follow-up of prostate carcinoma: "follow up echography in the course of drug therapy"]. FT Ecografia e follow up nel carcinoma della prostata: "follow up ecografico in corso di terapia medica".
No full textWhat does the urologist expect from the pathologist (and what can the pathologists give) in reporting on adult kidney tumour specimens?
No full textRole of PGE1 high dose in the echo colorDoppler study of the penis retrospective study on 900 patients
No full textEco colorDoppler flowmetry greatly increased the knowledge about penile erection. This diagnostic tool enables the study of arteriogenic erectile failure. We report on our six-year experience with this procedure on 900 men with erectile dysfunction. This experience lead us to standardise the method utilising high doses (20-40 μg) that minimise false negatives
[Transrectal echography of the prostate in the long-term follow-up of prostatic carcinoma in advanced stage]. FT L'ecografia transrettale della prostata nel follow-up a lungo termine del carcinoma prostatico in stadio avanzato.
No full textAndrogen deprivation therapy regulation of beta 1C integrin expression in prostate cancer
No full textThe β1C integrin is an alternatively spliced variant of the β1 integrin subfamily that at variance with its wild-type counterpart, i.e., the β1A integrin, inhibits cell proliferation in prostate cancer cells. We have recently shown that transcriptional, translational and post-translational processes contribute to the selective loss of β1C integrin during prostate malignant transformation. Here, we investigated whether androgen deprivation therapy (ADT) may affect β1C mRNA expression in prostate cancer. Neoplastic prostates were obtained from patients undergoing radical prostatectomy who had received neoadjuvant ADT. The β1C mRNA level was measured by Northern hybridization experiments and compared to normal prostates obtained from patients who underwent radical cystoprostatectomy for bladder cancer. Furthermore, the β1C integrin gene transcriptional activity was measured by nuclear Run-on assays. We found an increase of β1C mRNA expression (208±11%; p<0,01) in patients who received ADT in comparison to those who did not. Furthermore, we demonstrated an increase of gene transcriptional activity (360±10%; p<0,01) possibly partially or completely responsible for the regulation of the β1C integrin mRNA levels. Short-term administration of ADT seems to interfere with β1C integrin expression, suggesting the existence of androgen-mediated pathways involving β1C. Precise characterization of the mechanisms that regulate the expression of this factor in cancer cells will provide further insight into the molecular mechanisms involved in tumor progression and possibly contribute to the identification of molecular targets for the development of new therapeutic strategies
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