324,573 research outputs found
Dimmi cosa guardi e (non) ti dirò chi sei: riflessioni su modelli televisivi e identità di genere
No full textL'articolo analizza la relazione tra adolescenza e consumi televisivi mainstream interrogando il nesso con i processi di costruzione dell'identità maschile e femminile
Modeling the uniform transport in thin film SOI MOSFETs with a Monte-Carlo simulator for the 2D electron gas
No full textIn this paper, we present simulations of some of the most relevant transport properties of the inversion layer of ultra-thin film
SOI devices with a self-consistent Monte-Carlo transport code for a confined electron gas. We show that size induced quantization
not only decreases the low-field mobility (as experimentally found in [Uchida K, Koga J, Ohba R, Numata T, Takagi S. Experimental
eidences of quantum-mechanical effects on low-field mobility, gate-channel capacitance and threshold voltage of ultrathin body
SOI MOSFETs, IEEE IEDM Tech Dig 2001;633–6; Esseni D, Mastrapasqua M, Celler GK, Fiegna C, Selmi L, Sangiorgi E. Low
field electron and hole mobility of SOI transistors fabricated on ultra-thin silicon films for deep sub-micron technology application.
IEEE Trans Electron Dev 2001;48(12):2842–50; Esseni D, Mastrapasqua M, Celler GK, Fiegna C, Selmi L, Sangiorgi E, An experimental
study of mobility enhancement in ultra-thin SOI transistors operated in double-gate mode, IEEE Trans Electron Dev
2003;50(3):802–8. [1–3]]), but also the electron saturation velocity and the carrier heating depend on the subband structure, and thus
on the silicon film thickness
Traduzioni in lingua araba di testi della letteratura italiana del Novecento. Problemi linguistici e culturali
No full textThe research presented collects a first set of results identified an issue that is easy to grasp the significance, as well as a history of fortune abroad in our literature of the last century, an area of interest identified by the growing importance of cultural relations between Italy and the Arab world in recent decades are characterized by the phenomenon of migration had accelerated and enriched stimuli and urgent reasons for an overall comparison of horizons of civilization. If mediation in the Italian language of the Arabic literary heritage has a proven history of academic knowledge of the world's Arabic for Italian culture which is manifested through the translation of works of our literature is much more fragmented, as well as the other part still is the episodic story that she should testify. Attempts to identify more clearly the context of the Arabic translation of Italian literary texts that you can not remember many. Among the samples surveyed from the view of Dr. Selmi we merely recall the conventions of 1980 and 1993 respectively dedicated to the Italian cultural presence in Arab countries: history and prospects (Naples 28 to 30 May 1980), Translating and interpreting dialogue between Italy and the Maghreb (Carthage February 18, 1993) or more recently the intervention of Ahmed Soma, professor of Italian language and literature at the University of Tunis Manouba, international conference in Italian culture in the world (Pescara 2001). Even in these cases we noted a predominant focus, as understood in part, to the classics, which have a well-established preeminence in traditional representations of the historical story of Italian literature. The twentieth century section carves out a very limited space.La ricerca di cui la tesi presentata raccoglie una prima serie di risultati individua un tema di cui è agevole cogliere la rilevanza, oltre che per una storia della fortuna all'estero della nostra letteratura dell'ultimo secolo, per un ambito di interessi individuato dalla crescente importanza delle relazioni culturali tra l'Italia e il mondo arabo, caratterizzate negli ultimi decenni anche dal fenomeno della migrazione che ha accelerato e arricchito di stimoli e di urgenze le ragioni di un confronto complessivo di orizzonti di civiltà.
Se la mediazione in lingua italiana del patrimonio letterario arabo ha una sua consolidata storia accademica, la conoscenza dell'attenzione del mondo arabo per la cultura italiana che si manifesta attraverso la traduzione di opere della nostra letteratura è assai più frammentata, così come d'altra parte ancora episodica è la vicenda che essa dovrebbe testimoniare.
I tentativi di puntualizzare il quadro delle traduzioni in arabo di testi letterari italiani che è possibile ricordare non sono numerosi. Tra gli esempi censiti dalla tesi del dott. Selmi ci si limita a rammentare i convegni del 1980 e del 1993 dedicati rispettivamente a La presenza culturale italiana nei paesi arabi: storia e prospettive (Napoli 28-30 maggio 1980) e Tradurre e interpretare nel dialogo italo-maghrebino (Cartagine 18 febbraio 1993) o più recentemente all'intervento di Ahmed Somai, professore di lingua e letteratura italiana presso l'Università Manouba di Tunisi, nel convegno internazionale La cultura italiana nel mondo (Pescara 2001).
Anche in questi casi si prende atto di una attenzione prevalente, come in parte comprensibile, ai classici, che hanno una consolidata preminenza nelle tradizionali rappresentazioni storiche della vicenda della letteratura italiana. Il capitolo novecentesco si ritaglia uno spazio alquanto limitato
Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial (Nature Medicine, (2021), 27, 10, (1752-1760), 10.1038/s41591-021-01499-z)
No full textIn the version of this Article initially published, there was an error in the author affiliations. Specifically, affiliation 27, corresponding to author Carlo Selmi, has been corrected from “Humanitas Research Hospital, Milan, Italy” to read: “Department of Biomedical Sciences, Humanitas University, Milan, Italy & IRCCS Humanitas Research Hospital, Milan, Italy.” The change has been made to the online version of the Article
Macrophage activation syndrome in autoimmune disease
No full textMacrophage activation syndrome (MAS) is a phenomenon characterized by cytopenia, organ dysfunction, and coagulopathy associated with an inappropriate activation of macrophages. Current diagnostic criteria are imprecise, but the syndrome is now recognized as a form of hemophagocytic lymphohistiocytosis that is characteristically associated with autoimmune diatheses. The diagnosis of incipient MAS in patients with autoimmune disease requires a high index of suspicion, as several characteristics of the disorder may be present in the underlying condition or infectious complications associated with the treatment thereof. Proposed treatment regimens include aggressive approaches that require validation in future controlled studies. This review discusses the major aspects of the pathophysiology, diagnosis, and management of MAS with a focus on the association with autoimmune disease
Natural autoantibodies in the physiology and pathophysiology of the immune system
No full textNatural autoantibodies (autoNAb) recognize self antigens and are an important component of the immune system, as species ranging from invertebrates to vertebrates have polyreactive IgM NAbs. In higher vertebrates, different polyreactive autoNAbs isotypes are also frequently encountered and autopolyreactive IgG NAbs are largely predominant compared to low-titer monoreactive IgG NAbs specific for either self or non-self antigens. Autopolyreactive NAbs manifest the capacity to recognize three-dimensional structures and thus represent a fundamental feature of the immune system that has long been preserved during evolution. NAbs are produced in a continuum of functional and phenotypic tiers of B cells and are likely to derive from proteins initially selected to build the organism that were adapted through evolution to recognize environmental constituents, while preserving their capacity to recognize self antigens. The clonal selection is considered the predominant mechanism of the regulation of the immune system complexity but growing evidence suggests that autoNAbs are also actively implicated. In all species NAbs reacting with either self or non-self antigens constitute a vast network of infinite interactions providing high complexity, stability and plasticity. This evolutionary process was intended to allow the effective recognition of environmental antigens, immune memory, immunoregulatory phenomena, as well as tissue homeostasis. The present article is intended to illustrate the history and the current and future developments in our understanding of self and non-self recognizing NAbs to ultimately enlighten the complexity of the immune system regulation
The CORAIL(R) Hip System: a practical approach based on 25 years of experience
No full textJean-Pierre Vidalain, Tarik Aït Si Selmi, David Beverland, Steve Young, Tim Board Jens Boldt and Scott Brumb
Addressing the double burden of malnutrition in Egypt: do conditional cash transfers have a role?
No full textMany developing countries are undergoing rapid socio-economic changes that impact on health and its social distribution. These changes can occur so rapidly that there is a resulting co-existence of diseases of affluence and diseases of poverty. Priority setting for nutritional programs has focused on the alleviation of undernutrition in low income settings. However, evidence shows that in many Low-and-Middle Income Countries the prevalence of obesity among women is increasing and can coexist with childhood stunting. This dual burden of poor nutrition contributes to worsening health inequity between the poor and the rich. Global and national policy makers are looking for novel programs to replace social protection mechanisms deemed inefficient. Conditional Cash Transfer (CCT) programs have emerged as an increasingly popular poverty alleviation strategy with some positive results. However, there is evidence they may have a negative impact if the complexity of transition settings is not taken into account. In this paper, we review the nutritional situation in Egypt and compare two CCT programs (Mexico and Colombia) in an attempt to identify features that would address both child undernutrition and adult overnutrition. We conclude with suggestions for design of an Egyptian CCT program that would help maximise benefit to its beneficiaries
Storia della Cassa di Risparmio di Pistoia e Pescia. Credito, risparmio, territorio (1831-1992)
No full textLa Cassa di Risparmio di Pistoia e Pescia nasce dalla fusione di due istituti formatisi in territori geograficamente e storicamente assai diversi: la Cassa di Pistoia, nata nel 1831 in ambito urbano ma al centro di un vasto mondo rurale, inserita nella pianura di Prato e
Firenze; la Cassa di Pescia, nata nel 1840, nella cittadina più industriosa della Valdinievole, in un territorio allora assai fiorente e decisamente proiettato verso Lucca. Da secoli divise sotto il profilo amministrativo ed ecclesiastico, negli anni fra le due guerre Pistoia e Pescia si videro riunite in una stessa provincia: le due Casse furono protagoniste di una complessa operazione di incorporazione che diede origine a
un nuovo istituto creditizio capace di raccogliere quasi la metà dei depositi del territorio, diventando così la terza cassa di risparmio della Toscana. Questo libro ricostruisce, con una ricca documentazione archivistica, iconografica e quantitativa, la storia della Cassa di Risparmio di Pistoia e Pescia e dei due istituti che ne segnarono le origini. Una storia finanziaria e aziendale che si intreccia con le principali vicende politiche ed economiche del Paese: dalla restaurazione all’Italia liberale, al fascismo, attraverso guerre e crisi, fino ad arrivare al miracolo economico e alle riforme di fine XX secolo
Common variable immunodeficiency: etiological and treatment issues
No full textOne of the great advances in clinical medicine was the recognition of the pleomorphism of the immune response and the multiple afferent and efferent limbs of antigen processing and responsiveness. A significant contribution to this understanding was derived from studies of human immunodeficiency states, including both inherited and acquired syndromes. Amongst these syndromes, one of the most common, and least understood, is common variable immune deficiency (CVID). CVID is a syndrome that leads to a reduction in serum immunoglobulins and complications including recurrent infections. Management includes immunoglobulin replacement therapy; however, patients with CVID are at risk for complications of exogenous immunoglobulin administration as well as CVID-associated diseases such as autoimmune processes and malignancies. To assess the current state of knowledge in the field, we performed a literature review of a total of 753 publications covering the period of 1968 until 2008. From this list, 189 publications were selected for discussion. In this review, we demonstrate that while the molecular basis of CVID in many cases remains incompletely understood, significant strides have been made and it is now clear that there is involvement of several pathways of immune activation, with contributions from both T and B cells. Furthermore, despite the current gaps in our knowledge of the molecular pathogenesis of the syndrome, there have been dramatic advances in management that have led to improved survival and significantly reduced morbidity in affected patients
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