169,882 research outputs found

    CAD-based functional therapy during aligner treatment – the “En-Nova”-protocol (technical report)

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    Functional orthodontic therapy represents a fundamental element of orthodontic therapy, intending to correct skeletal discrepancies of growing patients by changing their neuromuscular patterns on the long run. To date, consequent functional orthodontic therapy is the first part of a two-phase treatment protocol, which is followed by subsequent dental alignment. For aligners several features are present, which aim to integrate functional therapy into aligner treatment. Examples include inclined planes (“precision wings”) incorporated into the aligners or elastics, both trying to force a mandibular advancement. However, all of them suffer from a rather small skeletal effect, which is why the development of new approaches, which allow for more growth control during aligner therapy, is justified. Against this background, the present article describes a new treatment concept which consists of a CAD-based functional orthodontic appliance overlaying over the aligners during the entire treatment time. By increasing the skeletal control, it is intended to guarantee a consequent functional orthodontic treatment while saving treatment time

    3D printed removable functional appliances for early orthodontic treatment – Possibilities and limitations

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    The early treatment of certain malocclusions, such as class II division 1, is recommended to decrease the likelihood of upper incisor trauma. However, the lack of skilled technicians and economic constraints prevent the availability of well-known removable functional appliances. The orthodontic profession is undergoing changes, and automation may offer a solution to these challenges. This article discusses the potential for automating the production of two commonly used removable orthodontic appliances. While CAD-CAM systems have streamlined dental manufacturing, 3D printing is a popular option for certain manufacturing processes. However, the adoption of 3D printing for orthodontic devices faces hurdles, such as redesigning devices for this new manufacturing process, material considerations, and necessary certifications. To showcase the potential design and manufacturing process of 3D printed devices that fall under the category of appliances similar in type and style to FR II and Sander II, the article centers on these two widely recognized appliances. As it is currently not possible to replicate all analog features in 3D, it may be appropriate to use a more general name for the FR II and Sander II appliances. In summary, the article examines the potential and limitations of automation in orthodontic appliance manufacturing

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Mitomycin C in highly myopic eyes - Author reply

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    Ophthalmology. 2005 Feb;112(2):208-18; discussion 219. Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes. Gambato C, Ghirlando A, Moretto E, Busato F, Midena E. SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy. Abstract PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes. DESIGN: Prospective, double-masked, randomized clinical trial. PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia. METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months). MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH. RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively). CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK. Comment in Ophthalmology. 2006 Feb;113(2):357; author reply 357-8

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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