1,720,975 research outputs found
An Evolutionary-Optimized Surgical Path Planner for a Programmable Bevel-Tip Needle
Path planning algorithms for steerable needles in medical applications must guarantee the anatomical obstacle avoidance, reduce the insertion length, and ensure the compliance with the needle kinematics. The majority of the solutions from the literature focus either on fast computation or on path optimality, the former at the expense of suboptimal paths, the latter by making unbearable the computation in case of a high-dimensional workspace. In this article, we implement a three-dimensional path planner for neurosurgical applications, which keeps the computational cost consistent with standard preoperative planning algorithms and fine-tunes the estimated pathways in accordance to multiple optimization objectives. From a user-defined entry point, our method confines a sample-based path search within a subsection of the original workspace considering the degree of curvature admitted by the needle. An evolutionary optimization procedure is used to maximize the obstacle avoidance and reduce the insertion length. The pool of optimized solutions is examined through a cost function to determine the best path. Simulations on one dataset showed the ability of the planner to save time and overcome the state of the art in terms of obstacle avoidance, insertion length, and probability of failure, proving this algorithm as a valid planning method for complex environments
Artificial intelligence for brain diseases: A systematic review
Artificial intelligence (AI) is a major branch of computer science that is fruitfully used for analyzing complex medical data and extracting meaningful relationships in datasets, for several clinical aims. Specifically, in the brain care domain, several innovative approaches have achieved remarkable results and open new perspectives in terms of diagnosis, planning, and outcome prediction. In this work, we present an overview of different artificial intelligent techniques used in the brain care domain, along with a review of important clinical applications. A systematic and careful literature search in major databases such as Pubmed, Scopus, and Web of Science was carried out using "artificial intelligence"and "brain"as main keywords. Further references were integrated by cross-referencing from key articles. 155 studies out of 2696 were identified, which actually made use of AI algorithms for different purposes (diagnosis, surgical treatment, intra-operative assistance, and postoperative assessment). Artificial neural networks have risen to prominent positions among the most widely used analytical tools. Classic machine learning approaches such as support vector machine and random forest are still widely used. Task-specific algorithms are designed for solving specific problems. Brain images are one of the most used data types. AI has the possibility to improve clinicians' decision-making ability in neuroscience applications. However, major issues still need to be addressed for a better practical use of AI in the brain. To this aim, it is important to both gather comprehensive data and build explainable AI algorithms
Data augmentation of 3D brain environment using Deep Convolutional Refined Auto-Encoding Alpha GAN
Learning-based methods represent the state of the art in path planning problems. Their performance, however, depend on the number of medical images available for the training. Generative Adversarial Networks (GANs) are unsupervised neural networks that can be exploited to synthesize realistic images avoiding the dependency from the original data. In this paper, we propose an innovative type of GAN, Deep Convolutional Refined Auto-Encoding Alpha GAN, able to successfully generate 3D brain Magnetic Resonance Imaging (MRI) data from random vectors by learning the data distribution. We combined a Variational Auto-Encoder GAN with a Code Discriminator to solve the common mode collapse problem and reduce the image blurriness. Finally, we inserted a Refiner in series with the Generator Network in order to smooth the shapes of the images and generate more realistic samples. A qualitative comparison between the generated images and the real ones has been used to test our model’s quality. With the use of three indexes, namely the Multi-Scale Structural Similarity Metric, the Maximum Mean Discrepancy and the Intersection over Union, we also performed a quantitative analysis. The final results suggest that our model can be a suitable solution to overcome the shortage of medical images needed for learning-based methods
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Inverse Reinforcement Learning algorithm for intra-vascular and intra-cardiac catheter’s navigation in Minimally Invasive Surgery
Structural Intervention Cardiology (SIC) is a miniinvasive intervention with a catheter based approach for cardiac surgery. Although SIC procedures are becoming increasingly popular, procedures are not ergonomic and technically demanding and, at the same time, high precision and accuracy in reaching target locations inside the human body are necessary for the success these procedures. Thus, there is therefore a need to develop a robust path planner framework to improve the accuracy in target reaching while minimizing interaction with anatomical structures. In this work a pre-operative path-planning method able to guide the catheter from the peripheral access to the desired target position with the needed orientation is proposed. The method exploits an Inverse Reinforcement Learning algorithm based on a combination of Behavioral Cloning (BC) and Generative Adversarial Imitation Learning (GAIL). The method was in-silico tested performing 50 intra-vascular and 70 intra-cardiac paths where the ratio between attempts in which the catheter reaches the target and total number of attempts, computation time, the difference between desired pose and the reached one were considered as validation metrics. Results show that the proposed method computes optimal path enabling the catheter to reach the target with an average error in position below 2 mm in the intra-vascular phase and below 1 mm in position and 6° in orientation in the intra-cardiac phas
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