12 research outputs found
Assessment of Landslide Susceptibility in the Himalayan Region: A Case Study of Rishikesh-Yamunotri Corridor
Get PDFThe findings of the statistical models based on geographic information systems (GIS) for creating landslip susceptibility maps utilising remote sensing data and geographic information systems for the Rishikesh to Yamunotri corridor of Uttarakhand are presented in this study. Cartosat, Landsat, IMD, and India water resources data were used to extract ten factors: slope, aspect, soil, lithology, NDVI, LULC, distance to stream, precipitation, distance to road, and elevation. Using GIS-based statistical models, such as the analytical hierarchy process (AHP), which assigns ranks and weights to various factors to determine which factors are more responsible for landslides, the relationships between the detected landslide locations and these ten related factors were identified. The three landslide zone categories, high, medium, and low, on the landslip inventory map were developed using various things like field surveys and digital aerial photos. Regional planning and hazard mitigation would benefit from these landslip susceptibility maps
Seismic Vulnerability Assessment of NCT of Delhi Using GIS-Based Multiple Criteria Decision Analysis
No full textLow-grade Cortisol Cosecretion Has Limited Impact on ACTH-stimulated AVS Parameters in Primary Aldosteronism.
Get PDFThis is a pre-copyedited, author-produced version of an article accepted for publication in Journal of Clinical Endocrinology and Metabolism following peer review. The version of record: Samuel Matthew O’Toole, Wing-Chiu Candy Sze, Teng-Teng Chung, Scott Alexander Akker, Maralyn Rose Druce, Mona Waterhouse, Sarah Pitkin, Anne Dawnay, Anju Sahdev, Matthew Matson, Laila Parvanta, William Martyn Drake, Low grade cortisol co-secretion has limited impact on ACTH-stimulated AVS parameters in primary aldosteronism, The Journal of Clinical Endocrinology & Metabolism, dgaa519, https://doi.org/10.1210/clinem/dgaa519CONTEXT: In primary aldosteronism, cosecretion of cortisol may alter cortisol-derived adrenal venous sampling indices. OBJECTIVE: To identify whether cortisol cosecretion in primary aldosteronism alters adrenal venous sampling parameters and interpretation. DESIGN: Retrospective case-control study. SETTING: A tertiary referral center. PATIENTS: 144 adult patients with primary aldosteronism who had undergone both adrenocorticotropic hormone-stimulated adrenal venous sampling and dexamethasone suppression testing between 2004 and 2018. MAIN OUTCOME MEASURES: Adrenal venous sampling indices including adrenal vein aldosterone/cortisol ratios and the selectivity, lateralization, and contralateral suppression indices. RESULTS: 21 (14.6%) patients had evidence of cortisol cosecretion (defined as a failure to suppress cortisol to ≤50 nmol/L post dexamethasone). Patients with evidence of cortisol cosecretion had a higher inferior vena cava cortisol concentration (P = .01) than those without. No difference was observed between the groups in terms of selectivity index, lateralization index, lateralization of aldosterone excess, or adrenal vein cannulation rate. CONCLUSIONS: Cortisol cosecretion alters some parameters in adrenocorticotrophic hormone-stimulated adrenal venous sampling but does not result in alterations in patient management
How behavioural science can help you find the right work with Dr Grace Lordan
No full textS2 Ep 5. Prof Grace Lordan is Author of Think Big, Associate Professor in Behavioural Science & Founder and Director of The Inclusion Initiative at the LSE. Grace used her behavioural science expertise to answer important questions, such as: How can someone in an established career get new skills and experiences in a different area? What role can inclusive leadership play in shaping the future of work? How can people overcome the psychological barriers like fear of failure or imposter syndrome to help them find the right work
Indexing of Journals and Indices of Publications
No full textJournal indexes are indicators toward the quality of a journal. Authors, researchers, and the audience need some criteria to judge which literature they need to read or which journal they need to send their article to. Journal indexes help the respective groups to make this decision. From Index Medicus to Web of Science, journal indexes use different criteria to judge the quality of a journal or an article. Figures like impact factor and CiteScore also rank journals and articles based on various criteria so that the audience and authors can make their pick. Author indices like h-index and ResearchGate score aid in comparing scientific work done by authors and researchers. Indexes of journals, publications, and authors therefore offer a classification of medical literature from which the best can be chosen depending on the requirements in their respective fields
MRI reporting standard for chronic pelvic pain:Consensus development
No full textAim: To identify radiological parameters that should be reported on gynaecological MRI in order to create a standardized assessment pro forma for reporting CPP, which may be used in clinical practice. Methods: Chronic pelvic pain (CPP) in females is a common problem presenting a major challenge to healthcare providers. The complex multifactorial aetiology requires a multidisciplinary approach and often necessitates diagnostic laparoscopy for assessment. MRI is emerging as a potential non-invasive alternative for evaluation of CPP; however, standardization of reporting is required for it to be used in routine clinical practice. A two-generational Delphi survey with an expert panel of 28 radiologists specializing in gynaecological MRI from across the UK was used to refine a proposed reporting template for CPP. Results: 75% response rate for the first round and 79% for the second. Following the second round, agreement was reached on the structure of the pro forma and the way in which information was sought, with overall consistency of agreement between experts deemed as fair (intraclass correlation coefficient50.394). This was accepted as the final version by consensus. Conclusion: The standardized pro forma developed in this study will form the basis for future prospective evaluation of MRI in CPP. This template could be modified for the assessment of other benign gynaecological conditions. Advances in knowledge: Female CPP is a significant problem presenting challenges for clinicians. MRI is often used for evaluation and standardization of techniques, and reporting is required. The pro forma developed in this study will form the basis for future prospective MRI evaluation.</p
MRI versus laparoscopy to diagnose the main causes of chronic pelvic pain in women: a test-accuracy study and economic evaluation
Get PDFNational Institute for Health Research (NIHR
Ovarian cancer screening in the general population.
No full textDespite significant improvements in therapy, ovarian cancer continues to be a leading cause of death amongst women with gynaecological malignancies. Advanced stage at diagnosis is thought to be a major contributor to mortality. Hence, there is considerable interest in early detection through screening. In the 1990s, Professor Jacobs pioneered the development of a multimodal ovarian cancer screening (OCS) strategy using serum CA125 as the first line screen and pelvic ultrasound as the second line test. This thesis summarises the next steps in the journey with refining of the screening algorithm, feasibility testing in a pilot randomised control trial (RCT) and finally setting up and recruiting 200,000 women into the largest ever RCT . The risk of ovarian cancer in postmenopausal women with elevated CA125 levels was established through a detailed analysis of 1219 pelvic scans from 741 women with raised CA125 levels in the completed trial of 22,000 women. Based on this, the multimodal 'Risk of Ovarian Cancer' (ROC) algorithm was refined and morphology instead of volume was used to interpret the ovarian scans. The refined ROC algorithm was then prospectively evaluated in a pilot RCT of 13,582 postmenopausal women. The trial established that screening using the ROC algorithm was feasible and could achieve high specificity and positive predictive value. The improved performance characteristics of the screening strategy and the experience accumulated in running and organising the pilot trial led to the design and successful implementation of a RCT - the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) - to assess the impact of early detection on disease mortality. The trial commenced in 2001 with recruitment of 202,638 postmenopausal women by September 2005. The issues involved in setting up the trial, recruitment of 202,000 women and the baseline characteristics of this population are described
Repatriation : factors related to individuals' expectations of international assignments
Get PDFThis thesis is
concerned with understanding the expectations that corporate
employees form
about the work- and career-related outcomes of an
international assignment.
Such
expectations are
frequently
cited as
being "unreasonable"
and a major
source of problems
in the repatriation and reintegration of
international
returnees.
There is, however,
a
lack of research evidence to indicate when
these expectations form, how they change with time, or what
factors influence
their formation.
The research takes a
UK
perspective in
view of the comparatively low levels
of
research into British international assignees
in
general and their motivations
and expectations in
particular.
The
author
believes this to be the first
study devoted
exclusively to the
expectations of
international assignees.
The
main stage of this research comprised of a postal survey to collect
information about
international assignees, about their work-related and career-
related expectations, and about a number of
factors
which might prove to be
precursors or predictors of expectations.
Data
were captured
from
a
comparatively
homogeneous
population comprising
British employees of
profit-making companies.
The
main contribution of this thesis is
an
increase in
our understanding of the
work-related and career-related expectations that corporate employees
form
when assigned overseas.
In
particular, the thesis increases our
knowledge
of
when these expectations
form; how they vary with time; and what personal
characteristics, actions taken by the employing organisation, and
characteristics of the assignment
itself
affect those expectations
during the
course of an
international assignment.
A secondary contribution of this thesis is to identify
a number of classes or
categories of assignment that appear to be intrinsically associated with
different types and degrees
of expectation
The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium
No full text
