103,708 research outputs found
83) M. SECHI NUVOLE - G. SERPILLO, Presentazione, “Atti della I edizione del Premio Internazionale Città di Sassari - Lingue minoritarie, culture delle minoranze” (a cura di),
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Synthesis and in vitro anticancer activity evaluation of biscarbamic esters of 2,3-bis(hydroxymethyl)-1-methyl-7- and 7,8-substituted- benzo[g]indoles
No full textA series of various bis(hydroxymethyl) carbamate derivatives of 7-mono- and 7,8-disubstituted- l-methyl-benzo[g]indoles was prepared in order to evaluate their cytostatic and cytotoxic activities in vitro. Compounds 2a-h showed significant tumor growth inhibition activity and were more potent than the 4,5-dihydrobenzo[g] indole analogues previously described. Compound 2a was the most active in this series, showing high activity and selectivity for some human cancer cell lines in the National Cancer Institute screen
Conflitti di comunicazione e conflitti di identificazione nella balbuzie in età evolutiva
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Visuo-spatial processing in learning disabled children with minor neurological disfunction
No full textIl trattamento farmacologico dei disturbi di apprendimento. Note sull’uso degli psicostimolanti
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Mixed optimization technique for large scale water-resource systems
No full textDealing with significantly large design problems for water-resource systems a mixed optimization procedure based on network linear programming and the subgradient method will be described. Using a linear problem formulation, the procedure uses network linear programming as a subproblem that assumes the knowledge of design variables. Since inside its domain, the global objective functions is a convex piecewise linear function, a subgradient method is used to obtain the direction of the improvement of design variables at each iteration using the solutions of the network subproblem. The mixed technique permits an efficient evaluation of the design variables in order to reach a good approximation of the global objective function optimum. The solution technique performs well in the purely linear case and, moreover, allows some kinds of nonlinearities in the cost functions of design variables
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