1,720,965 research outputs found
Preoperative pulmonary rehabilitation in lung cancer patients undergoing lung resection surgery
Get PDFPrograma Oficial de Doutoramento en Saúde, Discapacidade e Dependencia. 560V01[Abstract]
INTRODUCTION: Lung resection surgery (LRS) remains the treatment of choice for early
stages of lung cancer but significant morbidity is associated, especially among patients with
poor preoperative status. Preoperative exercise training (PET) has been proposed as an
effective way of optimizing patients’ condition before surgery and enhancing postoperative
recovery. However, it remains unknown whether or not similar results can be achieved after
video-assisted thoracic surgery (VATS). Therefore, the aim of this thesis is to determine the
feasibility, safety and efficacy of a preoperative pulmonary rehabilitation program (PPRP) on
the functional and postoperative outcomes on patients undergoing VATS.
MATERIALS AND METHODS: This thesis was structured in three studies: 1) a systematic
review and meta-analysis of the effects PET on the functional and postoperative outcomes
after LRS; 2) a small pilot investigation to assess the feasibility, safety and preliminary
effects of a PPRP in patients awaiting VATS; and 3) a randomized controlled trial examining
the effects of the PPRP after VATS for lung cancer on selected postoperative and functional
outcomes in comparison to the standard care.
RESULTS: Results from the study #1 show that PET improves pulmonary function before
surgery and hastens postoperative recovery by reducing postoperative complications and
hospital length of stay. In study #2, we concluded that a PPRP is safe and feasible and can
potentially improve functional fitness. Finally, study #3, confirmed that a PPRP significantly
improves exercise capacity, muscle strength and health-related quality of life while
minimizing the impact of LRS during the first 3 months after VATS.
CONCLUSIONS: We conclude that preoperative exercise-based interventions in patients
with lung cancer awaiting VATS are feasible, safe and can significantly improve exercise and functional performance and enhance postoperative recovery.[Resumen]
INTRODUCCION: La cirugía de resección pulmonar (CRP) continúa siendo el tratamiento
de elección en estadios iniciales del cáncer de pulmón pero la morbilidad asociada continúa
siendo elevada, especialmente en pacientes con peor condición física. La Rehabilitación
Pulmonar Preoperatoria (RPP) podría constituir una herramienta útil a la hora de disminuir el
riesgo perioperatorio y optimizar la recuperación postoperatoria. Sin embargo, dichos
programas no han sido probados en pacientes operados por videocirugía. Así pues, el objetivo
de esta tesis es investigar la viabilidad, seguridad y eficacia de un programa de RPP en
pacientes sometidos a resección pulmonar por videocirugía.
MATERIAL Y METODOS: Esta tesis está estructurada en tres estudios: 1) revisión
sistemática y meta-análisis sobre la eficacia del ejercicio preoperatorio en pacientes
sometidos a CRP en cuanto a mejorar el estado funcional de los pacientes y acelerar la
recuperación postoperatoria; 2) estudio piloto centrado en la viabilidad, seguridad y eficacia
preliminar de la RPP en pacientes sometidos a videocirugia; y 3) un ensayo controlado
aleatorizado sobre la eficacia de la RPP en los outcomes funcionales y postoperatorios en
pacientes sometidos a videocirugia en comparación con el tratamiento estándar.
RESULTADOS: Los resultados obtenidos en el estudio #1 muestran que el ejercicio
preoperatorio mejora la función pulmonar y acelera la recuperación postoperatoria al reducir
la estancia hospitalaria y el número de complicaciones; con el estudio #2 se comprobó que la
RPP es viable, segura y potencialmente eficaz a la hora de incrementar la capacidad
funcional, mientras que el estudio #3 corroboró los resultados anteriores demostrando que la
RPP incrementa la tolerancia al esfuerzo, la fuerza muscular y la calidad de vida al tiempo
que optimiza la recuperación postoperatoria los tres primeros meses tras videocirugia.
CONCLUSION: La RPP en pacientes con cáncer de pulmón sometidos a videocirugia es
viable, segura y eficaz a la hora de incrementar el estado funcional preoperatorio de los
pacientes así como optimizar la recuperación postoperatoria.[Resumo] INTRODUCCION: A cirurxía de resección pulmonar (CRP) constitue o tratamiento de
elección en pacientes con cancro de pulmón en estadios iniciáis pero a morbilidade asociada
continua a ser elevada especialmente en pacientes con peor condición física de base. Neste
contexto, a Rehabilitación Pulmonar Preoperatoria (PRP) podería considerarse como unha
ferramenta útil para disminuir o risco quirúrxico e optimizar o estado funcional dos pacientes.
Non obstante, desconecese o rol destos programas nos pacientes operados por videocirurxía.
Así pois, o obxectivo desta tese de doutoramento e estudar a viabilidade, seguridade e
eficacia da Rehabilitación Pulmonar Preoperatoria (RPP) en pacientes con cancro de pulmón
sometidos a resección pulmonar por videocirurxía.
MATERIAL E METODOS: Esta tese está estructurada en tres estudos: 1) revisión
sistemática e meta-analice da efectividade da RPP en pacientes con cancro de pulmón
sometidos a CRP para mellorar o estado funcional e acelerar a recuperación postoperatoria;
2) estudo piloto sobre a viabilidade, seguridade e eficacia preliminar da RPP en pacientes
operados por videocirurxía e 3) ensaio clínico aleatorizado sobre o impacto da RPP sobre a
tolerancia o esforzo, a capacidade funcional e a tolerancia o esforzo no postoperatorio de
CRP en comparación co tratamento estándar.
RESULTADOS: Os resultados obtidos no estudo #1 mostraron que o exercicio preoperatorio
en pacientes sometidos a CRP mellora a función pulmonar e acelera a recuperación
postoperatoria ao reducir o número de complicacións postoperatorias e a estadía hospitalaria;
no estudo #2 quedo comprobada a viabilidade da intervención así como a ausencia de eventos
adversos así como o potential da intervención para mellorar a funcionalidade dos pacientes;
finalmente, o estudo #3 corroborou a efectividade da RPP para optimizar o estado funcional
v | P a g e
dos pacientes previo a cirurxía e disminuir o impacto ocasionado pola CRP durante os tres
primeiros meses tras videocirurxía.
CONCLUSIÓNS: A RPP en pacientes con cancro de pulmón sometidos a videocirurxía e
viable, segura e eficaz para incrementar a tolerancia o estado funcional previo a cirurxía e
optimizar a recuperación postoperatoria
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Effect of pre-operative pulmonary rehabilitation in lung cancer patients
Get PDF[Resumen] El cáncer de pulmón constituye una de las principales causas de muerte en los países desarrollados. Los tratamientos utilizados frecuentemente conducen a un deterioro en la calidad de vida y la capacidad funcional de los pacientes. Las principales bases de datos han sido revisadas entre febrero y marzo de 2012 para evaluar el papel que ejercen los programas de rehabilitación pulmonar (RP) en el preoperatorio de cirugía torácica y sus efectos sobre el postoperatorio inmediato. De los 425 artículos identificados, finalmente 9 cumplieron los criterios de inclusión establecidos. De los datos extraídos, podemos concluir que los programas de RP son efectivos para mejorar la tolerancia al esfuerzo en los pacientes, aunque son necesarios más estudios controlados para establecer diferencias significativas en otros aspectos como la función pulmonar o la calidad de vida.[Abstract] Lung cancer is considered as one of the leading causes of death in developed countries. The therapies used for the treatment often lead to a deterioration in the patient's quality of life and functional capacity. The main data bases were searched between February and March 2012 in order to evaluate the role of pulmonary rehabilitation (PR) programs during the thoracic surgery preoperative period and their effects on the immediate post-surgery period. Finally, 9 out of the 425 papers identified met the inclusion criteria. Based on the data obtained, we can conclude that the PR programs are effective to improve tolerance to exercise in lung cancer patients. However, more randomized controlled trials are needed to establish significant differences in other aspects such as lung function or quality of life
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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