298 research outputs found
A TALE OF TWO CITIES: DIET, HEALTH AND MIGRATION IN POST-MEDIEVAL COVENTRY AND CHELSEA THROUGH BIOGRAPHICAL RECONSTRUCTION, OSTEOARCHAEOLOGY AND ISOTOPE BIOGEOCHEMISTRY
No full textBiogeochemical research has over the past four-and-a-half decades improved our understanding of human interaction with past environments. The application of different isotope systems has allowed archaeologists to interpret ancient diet, migration and pollution. Although well established in archaeology, biogeochemical interpretations are burdened with questions not only as to the methodology employed but also whether the data presents a consistent picture of past human activity. The use of biographically identifiable individuals offers a means by which the isotope systems may be tested against extent documentary evidence. A sample of forty-five individuals, almost half of which were named individuals, were obtained from the sites of Holy Trinity (Coventry) and St. Luke's (Old Street, Chelsea) and the stable isotopes of carbon, nitrogen, oxygen, strontium and lead analysed. The biographies ofthe named individuals were reconstructed through analysis ofextant historical documentation and' used to provide a framework of interpretation for the biogeochemical teclmiques applied. Comparisons are made between the two sites in relation to the biogeochemical techniques employed, biographical reconstruction and osteoarchaeological evidence for disease, migration and diet to address methodological issues and broader questions on 'i,ndustrialisation' during the eighteenth and nineteenth centuries. The osteoarchaeological evidence suggests separation of the two groups into discrete' populations, one that is characterised by occupationally-derived osteoarthropathies (Coventry), and the second, Chelsea, which has an absence of these pathologies. This supports the historical character of the t\VO cities: Coventry as an industrial city in contrast to Chelsea, a 'village of palaces' or pleasure resort. Biogeochemically, carbon and nitrogen isotopes revealed a picture of status-based access to protein resources in a diet that is particularly dominated by freshwater fish, terrestrial omnivores such as pig, or a combination of the two. There is, however, little evidence for a difference in access to such resources between the sexes. Likewise, strontium and oxygen isotopes are capable of differentiating between the two populations and therefore in identifying local and migrant individuals, though limitations in the sample prevent the full utilisation of this data. In one case (Milborough Maxwell) the isotopic techniques \vere able to reveal trans-Atlantic migration between England and the Caribbean. Analysis of lead isotopes of the two populations indicates that while there is little to differentiate the two sites, heavy metal exposure is greater for the eighteenth and nineteenth centuries than for previous periods.EThOS - Electronic Theses Online ServiceGBUnited Kingdo
A politics of conversion: nihilism and love in Toni Morrison's fiction
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-Graduação em Letras.O estudo Uma Política de Conversão: Niilismo e Amor na Ficção de Toni Morrison começa com a idéia de que a Literatura Afro-Americana apresenta um sentido de auto-reflexividade e hibridismo, através do qual autobiografia dialoga com romance, o espiritual se funde com o político. A partir deste traço dialógico a auto-reflexividade é politicamente estabelecida entre niilismo e amor. Na política de conversão, o estudo analisa as formas como mulheres negras, individualmente ou em grupo, fogem da escravidão para a liberdade, avançam da individualidade para a coletividade, ou substituem niilismo por amor. Metodologicamente o estudo apresenta sete capítulos. O primeiro discute os aspectos dialógicos que ilustram as conexões entre narrativas espirituais, de escravos e ficção, entre espiritualidade e política. O segundo examina o diálogo entre a conversão, pregação pública e formação da comunidade em Diário e Experiências Religiosas de Lee. O capítulo sugere que ao afirmar espiritualidade e humanidade a narradora abre profundo espaço para a mulher negra reclamar direitos civis. O terceiro discute o diálogo no interior da política de conversão entre narrativa de escravos e ficção. Este diálogo lida com niilismo e amor em Incidentes de Jacobs e Amada, Sula e O Olho Mais Azul de Morrison. Para a análise de niilismo e amor valores individuais e coletivos são considerados em relação a cinco aspectos: ambiente e agente antagonistas, agente de apoio, propósito da personagem e resultado alcançado. É visível, no estudo, o apoio que certas mulheres recebem de suas comunidades para contra-atacar antagonistas. O apoio nem sempre resulta na superação do niilismo e, por isso, derrota temporária pode ocorrer antes que elas sejam reintegradas à comunidade, como acontece com Linda Brent. O quarto capítulo examina as fraquezas e as energias da política da conversão e a reintegração de Sethe Suggs à comunidade de Bluestone Road. O quinto avalia como a comunidade de Bottom tenta controlar a individualidade de Sula Peace e como um grupo de mulheres lideradas por Nel Wrights consegue resgatar o espírito de independência da heroína. O sexto mostra como a política da conversão das mulheres de Lorain é incapaz de garantir a saúde mental de Pecola Breedlove, mas consegue criar um papel mais consistente para o grupo. No sétimo, a conclusão examina da relação dialética entre niilismo e amor ou auto-amor nas experiências dos indivíduos e dos grupos. O estudo sugere que em Incidentes a busca de Linda Brent por liberdade envolve elementos de autodestruição e de autoempoderamento. Da mesma maneira, o estudo conclui que em Amada o amor que Sethe Suggs tem para as suas crianças mata a própria filha, enfatizando, assim, o desejo de livrá-la da escravidão. Igualmente em Sula, a individualidade de Sula Peace não apenas limita, mas também expande as experiências do grupo, levando-o à emancipação. Finalmente, em O Olho Mais Azul a luta de Pecola Breedlove por amor e beleza reflete auto-ódio ao mesmo tempo em que reconstrói a auto-apreciação de toda a comunidade
Malate dehydrogenase 1 (MDH1) in nuclear and cytoplasmic homogenates of <i>X</i>. <i>laevis</i> oocytes.
No full textHuman UniProt link in Kirli et al., 2015: P40925 · MDHC_HUMAN. Malate dehydrogenase activity in homogenates of whole cytoplasms and whole nuclei (whole cell activity was previously characterized by Gill and Schultz (2022), who also reported on the expression of full-length MDH1 in these compartments). In the present study enzyme activity was analyzed as described for whole oocyte homogenates by Gill and Schultz (2022). Gill GS, Schultz MC. Multienzyme activity profiling for evaluation of cell-to-cell variability of metabolic state. FASEB BioAdv. 2022;4:709–723. (PDF)</p
Molecular gas in dusty high-redshift galaxies
No full textWe present high-resolution observations of carbon monoxide (CO) emission lines for three high-redshift galaxies in order to determine their molecular gas and star formation properties. These galaxies (SMM J14011+0252, SMM J00266+1708, and SDSS J0901+1814) have large infrared luminosities, which imply high dust enshrouded star formation rates and substantial molecular gas masses. We observed these sources using the Robert C. Byrd Green Bank Telescope, the Karl G. Jansky Very Large Array, the Plateau de Bure Interferometer, and the Submillimeter Array in order to obtain measurements of multiple CO spectral lines, allowing us to determine the physical conditions of the molecular gas. Our high resolution and multi-line CO mapping of SMM J00266+1708 reveals that it is a pair of merging galaxies, whose two components have different gas excitation conditions and different gas kinematics. For SMM J14011+0252 (J14011), we find a near-unity CO(3-2)/CO(1-0) intensity ratio, consistent with a single phase (i.e., a single temperature and density) of molecular gas and different from the average population value for dusty galaxies selected at submillimeter wavelengths. Our radiative transfer modeling (using the large velocity gradient approximation) indicates that converting the CO line luminosity to molecular gas mass requires a Galactic (disk-like) scale factor rather than the typical conversion factor assumed for starbursts. Despite this choice of conversion factor, J14011 falls in the same region of star formation rate surface density and gas mass surface density (the Schmidt-Kennicutt relation) as other starburst galaxies. SDSS J0901+1814 (J0901) was initially selected as a star-forming galaxy at ultraviolet wavelengths, but also has a large infrared luminosity. We use the magnification provided by the strong gravitational lensing affecting this system to examine the spatial variation of the CO excitation within J0901. We find that the CO(3-2)/CO(1-0) line ratio is higher in central regions than in extended structure, supporting a picture of the molecular gas where regions of higher excitation gas (higher temperature and density) are embedded in an extended low excitation phase. We also examine the resolved Schmidt-Kennicutt relation as a function of CO line excitation for J0901 and find no systematic difference between the best-fit power law indices for the two emission lines.Ph. D.Includes bibliographical referencesby Chelsea Electra Sharo
Environmental Attitudes and Behaviors Across Cultures
No full textOne of the fundamental aspects of culture is the relationship it prescribes between individuals and environment. Am I part of the natural environment, or am I separate and perhaps superior to nature? The answer to this question influences the types of attitudes that individuals within a given culture are likely to develop, the types of environmental behaviors that individuals are likely to adopt, and more generally, beliefs about how to solve environmental problems. This chapter examines differences in attitudes about environmental issues across cultures. We distinguish between egoistic environmental attitudes, and biospheric environmental attitudes, and summarize recent cross-cultural research on the relationship between cultural values and attitudes about the natural environment
(The) man, his body, and his society: masculinity and the male experience in English and Scottish medicine c.1640-c.1780.
No full textThis thesis examines the relationship(s) between medicine, the body and societal codes of masculinity in England and Scotland between c.1640 and c.1780. It responds to the way in which the men in histories of post-1660 masculinity are often disembodied, and to the comparative absence of men’s gendered experiences from the history of medicine. Its findings show that in both centuries the experience of being a man with a body that was the site of health and sickness was an open, candid, and often communal, one, inside and outside of the formal medical encounter. Thus, and on both sides of 1700, ill men had full freedom in the pursuit and acceptance of medical, familial and social assistance, while their physical suffering, and associated emotional distress, was met with sympathy. With their sick bodies the sites of honest self-examination and open discussion, it was in part this very public nature of their sicknesses that allowed men, as a gender and as individuals, independence and agency in their non-commercial health care. Indeed, later-seventeenth- and eighteenth-century men suffered no constraints in their ability to respond to the vulnerabilities of their bodies, even where this involved behaviours or attributes allegedly associated with women and femininity, or inconsistent with ideals of active, independent, masculinity.
These findings indicate, therefore, great continuity across the period 1640-1780, and not only in masculine ideals of and involving the male corporeality. There seems to have been significant consistency across time in men’s social and medical experiences of both sickness and their pre-emptive preparation for it, and in an apparent collective self-confidence concerning their corporeal masculinity, their sex, and, possibly, even their sexual potential. Indeed, these sources suggest that seventeenth- and eighteenth-century men had a resilient sense of self-identity (and personal masculinity), conceptually separable from the corporeal body and its known fragilities
LC-MS data for Figs 1F and 3A.
No full text*Data for cytosol previously reported in: Gill GS, Schultz MC. Multienzyme activity profiling for evaluation of cell-to-cell variability of metabolic state. FASEB BioAdv. 2022;4:709–723. **Nuclear expression confirmed by Western blotting–see S8, S9A and S9B Figs. (PDF)</p
Analysis of Self: My Journey to Healing and Helping
No full textThe Analysis of Self led me to take an inventory of who I am as a person and a professional, and what led me to where I am today as a Clinical Mental Health Counselor. This project satisfies the requirements of the graduate program. Besides taking an in-depth overview of my personal history, I also included assessments such as the Myers-Briggs Type Indicator (MBTI) and the Strong’s Interest Inventory (SII) to uncover various aspects of my personality, strengths and qualities. Interventions that align with my counseling style are Cognitive Behavioral Therapy, Trauma-Focused Cognitive Behavioral Therapy, and Person-Centered Therapy because of their evidence-based success and because of the population I intend to work with.. Interviews were conducted to gain an outsider’s view into my growth and counseling style
Chelsea Manning and the Contemporary Intelligence Whistleblower : Prescriptions for the 21st Century
No full textiii, 94 p.Instead of an act of betrayal, principled whistle blowing ought to be considered a different realization of the sworn oath to one's country. Political scientist C. Fred Alford stated, "A real cynic isn't going to blow the whistle. A real conformist isn't going to blow the whistle. And a real radical probably won't be in a position to do it. It takes someone who believes in the system far more than the system believes in itself' (Abraham 2004). Whistleblowers such as Chelsea Manning serve their civic post until a realization of wrongdoing introduces a choice-whether or not to disclose this abuse, to what source, and with what expected outcome. This work explains the ways in which a contemporary intelligence sector employee may reach this decision, taking into account the nature of the information, deficiencies in the traditional method of reporting and the likelihood that the disclosure will be meaningfully addressed, alternative means of disclosure, and the subsequent charges and court conditions that will likely occur. The indications of these factors may appear pessimistic, but we are entering an era where the names of whistleblowers are increasingly found in common discourse, and their disclosures have members of the public demanding more governmental accountability. Individuals with the courage to disclose wrongdoing will exist even in the case of such chilling precedent, but it is in the best interest of the U.S. government and public to be receptive to these individuals and penalize the exposed wrongdoings instead of those who reveal them. The author reviews the case of intelligence analyst Chelsea Manning (formerly known as Bradley Manning) who questioned the morality of the U.S. operation in Iraq and after contacting the Washington Post and the New York Times disclosed the Iraq and Afghanistan War Logs, the “Collateral Murder” video, and diplomatic cables from the State Department to the online news site WikiLeaks. Also included is an overview and critique of Manning’s trial. Finally the author considers the role and characteristics of the act of whistleblowing in the 21st Century
- …
