40 research outputs found
PERANAN LEMBAGA SOSIAL RIFKA ANNISA DALAM MEMBERIKAN PERLINDUNGAN BAGI ISTRI KORBAN KEKERASAN DALAM RUMAH TANGGA
No full textThe legal research title is “The Role of Social Institutions Rifka Annisa In Wife Gives Protection
For Victims of Domestic Violence”. The goal is to know Role of Social Institutions Rifka Annisa
in providing protections for the wife of Domestic Violence Victims and to know the constraints
experienced by the Instite od Social Rifka Annisa in providing protection for the wife of
Domestic Violence Victims. Normative study was conducted, using secondary data consisting of
primary, secondary legal materials, and tertiary. Research and interviews, with the resources to
obtain information needed by the author, carried outing searching for thr source data, the authors
also use qualitative methods to think with deductive reasoning in drawing conclusions. The
conclusion is a form of protection provided Rifka Annisa Institute For Wife Victims of Domestic
violence is provide assistance to victims of domestic violence and provide protection in the form
of counseling to strengthen and provide security for victims, providing information on the rights
of victims to obtain protection, as well as delivering coordination with institutions and agencies –
agencies. If the victim’s lack of support from fmily and gets a serious threat then the victim will
be placed in shelter cooperation between the private parties and government. With a good
relationship good in will lead to better protection again. So that later is expected that domestic
violence will not happen again in a household
Dexamethasone Use and Insulin Requirements in Coronovirus-19 (COVID-19) Infection Stratified by Hemoglobin A1c
No full textAims: The study aimed to identify weight-based insulin requirements for dexamethasone-induced hyperglycemia in COVID-19 infection stratified by hemoglobin A1c (HbA1c). Methods: This retrospective study assessed hospitalized patients ≥ 18 years admitted with COVID-19 and receiving ≥ 1 dose of dexamethasone 6 mG. Daily blood glucose (BG) and insulin doses were collected and organized by HbA1c. Results: Among 45 patients with available HbA1c, 100% [HbA1c ≥ 7%] and 72% [HbA1c < 7%] developed hyperglycemia (BG ≥180 mG/dL). Median daily insulin (Interquartile Range) (units/kG/day) was 0.03 (0, 0.32) [HbA1c 6–6.9%], 0.1 (0.06, 0.36) [HbA1c 7–7.9%], 0.66 (0.39, 0.69) [HbA1c 8–8.9%], and 0.72 (0.63, 0.78) [HbA1c ≥ 9%]. On day 10 of dexamethasone, when majority of patients were at goal BG, patients required 0.07 (0.01, 0.31) [HbA1c 6–6.9%], 0.59 (0.11, 0.75) [HbA1c 7–7.9%], 1.15 (0.95, 1.35) [HbA1c 8–8.9%], and 1.14 units/kG/day [HbA1c ≥ 9%]. Of 24 patients completing 10 days of dexamethasone, 25% experienced hypoglycemia (BG < 70 mG/dL) upon discontinuation. Conclusion: Patients with higher HbA1c experienced greater dexamethasone-induced hyperglycemia and required higher insulin doses. Inpatient insulin dosing algorithms should take into consideration baseline HbA1c to avoid delays in achieving normoglycemia
Multidisciplinary management of endocrinopathies and treatment‐related toxicities in patients with Bloom syndrome and cancer
No full textThe treatment of malignancy in cancer predisposition syndromes that also confer exquisite sensitivity to standard chemotherapy and radiation regimens remains a challenge. Bloom syndrome is one such disorder that is caused by a defect in DNA repair, predisposing to the development of early-onset age-related medical conditions and malignancies. We report on two patients with Bloom syndrome who responded well to chemotherapy despite significant alterations to standard protocols necessitated by hypersensitivity. Both patients experienced severe toxicities and exacerbation of endocrine comorbidities during chemotherapy. A multidisciplinary team of oncologists and endocrinologists is best suited to care for this patient population
Assembling a single-molecule view on nucleosome dynamics
No full textThe main focus of this thesis is a better understanding of the basic compaction mechanism of our DNA using multiple single-molecule techniques. The stretched-out length of our DNA is enormous compared with the dimensions of a cell. To make DNA fit within a cell it is systematically wrapped around proteins (histone octamers), forming nucleosomes. Besides compacting, nucleosomes also decrease the necessary accessibility of DNA for important processes like transcription and replication. The dynamical interplay between DNA and proteins ensures the right balance between compact and accessible DNA, but is not yet fully understood. Therefore, we study the process of nucleosome assembly as well as the dynamics of nucleosomes at the single-molecule level. Furthermore, we investigate proteins that probe the conformation of the DNA helical structure.BionanoscienceApplied Science
Extraction of pectin from passion fruit rind (Passiflora edulis var. flavicarpa Degener) for edible coating
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