1,402 research outputs found
Ventilation-perfusion ratio in perflubron during partial liquid ventilation
No full textBACKGROUND: Functional magnetic resonance imaging (fMRI) of fluorine-19 allows for the mapping of oxygen partial pressure within perfluorocarbons in the alveolar space (Pao(2)). Theoretically, fMRI-detected Pao(2) can be combined with the Fick principle approach, i.e., a mass balance of oxygen uptake by ventilation and delivery by perfusion, to quantify the ventilation-perfusion ratio (Va/Q) of a lung region: The mixed venous blood and the inspiratory oxygen fraction, which are equal for all lung regions, are measured. In addition, the local expiratory oxygen fraction and the end capillary oxygen content, both of which may differ between the lung regions, are calculated using the fMRI-detected Pao(2). We investigated this approach by numerical simulations and applied it to quantify local Va/Q in the perfluorocarbons during partial liquid ventilation. METHODS: Numerical simulations were performed to analyze the sensitivity of the Va/Q calculation and to compare this approach with another one proposed by Rizi et al. in 2004 (Magn Reson Med 2004;52:65-72). Experimentally, the method was used during partial liquid ventilation in 7 anesthetized pigs. The Pao(2) distribution in intraalveolar perflubron was measured by fluorine-19 MRI. Respiratory gas fractions together with arterial and mixed venous blood samples were taken to quantify oxygen partial pressure and content. Using the Fick principle, the local Va/Q was estimated. The impact of gravity (nondependent versus dependent) of perflubron dose (10 vs 20 mL/kg body weight) and of inspired oxygen fraction (Fio(2)) (0.4-1.0) on Va/Q was examined. RESULTS: In numerical simulations, the Fick principle proved to be appropriate over the Va/Q range from 0.02 to 2.5. Va/Q values were in acceptable agreement with the method published by Rizi et al. In the experimental setting, low mean Va/Q values were found in perflubron (confidence interval [CI] 0.08-0.29 with 20 mL/kg perflubron). At this dose, Va/Q in the nondependent lung was higher (CI 0.18-0.39) than in the dependent lung regions (CI 0.06-0.16; P = 0.006; Student t test). Differences depending on Fio(2) or perflubron dose were, however, small. CONCLUSION: The results show that derivation of Va/Q from local Po(2) measurements using fMRI in perflubron is feasible. The low detected Va/Q suggests that oxygen transport into the perflubron-filled alveolar space is significantly restrained
Effects of fentanyl and S(+)-ketamine on cerebral hemodynamics, gastrointestinal motility, and need of vasopressors in patients with intracranial pathologies - A pilot study
No full textIn neurosurgical patients, opioids are administered to prevent secondary cerebral damage. Complications often related to the administration of opioids are a decrease in blood pressure affording the use of vasopressors and intestinal atonia. One alternative approach to opioids is the application of S(+)ketamine. However, owing to a suspected elevation of intracranial pressure (ICP), the administration of S(+)-ketamine has questioned for a long time. The aim of the present study was to evaluate ICP, gastrointestinal motility, and catecholamine consumption in neurosurgical patients undergoing 2 different protocols of anesthesia using fentanyl or S(+)-ketamine. Twenty-four patients sustaining traumatic brain injury or aneurysmal subarachnoid hemorrhage received methohexitone plus either fentanyl or S(+)-ketamine to establish a comparable level of sedation. To reach an adequate cerebral perfusion pressure (CPP), the norepinephrine dosage was adapted successively. Enteral nutrition and gastrointestinal stimulation were started directly after admission on the critical care unit. ICP, CPP, and norepinephrine dosage were recorded over 5 days and also the time intervals to full enteral nutrition and first defecation. There was no difference regarding ICP, CPP, and the time period until full enteral nutrition or first defecation between both groups. Patients who underwent analgesia with S(+)ketamine showed a trend to a lower demand of norepinephrine compared with the fentanyl group. Our results indicate that S(+)-ketamine does not increase ICP and that its use in neurosurgical patients should not be discouraged on the basis of ICP-related concerns
NJBankers 2015 Economic Survey: Final Analysis and Report of Survey Findings
No full textThis is the fifth annual Economic Survey. The survey inquires about national and state current economic assessments, as well as six-month projections; expectations about long-term and short-term interest rates; commercial real estate submarket and loan demand; and residential loan and refinance demand. The survey also explores real estate values, currently and expected, as well as a set of negative indicators and common obstacles to lending. The survey series probes metrics about the national, state, and banking market economies in order to better understand, and, in turn, better facilitate the growth, development, and common interests of the banking sector in the state of New Jersey. Conducted by the Bloustein Center for Survey Research (BCSR) under the direction of James Hughes, Marc Weiner and BCSR senior research specialist Orin Puniello,Conducted for New Jersey Bankers Association"January 2015
Friends of the Greenwood Library Presents Marc Leepson
No full textOn Tuesday, September 11, 2012 the Friends of the Janet D. Greenwood Library hosted its fall event, which featured an evening with Marc Leepson. Leepson is a journalist, historian and the author of seven books, including Lafayette: Lessons in Leadership from the Idealist General (Palgrave/Macmillan, 2011), a concise biography of the famed Marquis de Lafayette
NJBankers 2017-18 Economic Survey: Final Anaylsis and Report of Survey Results
No full textUnder the direction of James Hughes, the Bloustein School surveyed all 92 member institutions of the New Jersey Bankers Association and received a 73 percent response rate.
This year’s survey results indicate a soaring confidence in the US economy. Nearly 85 percent of respondents indicated the national economy’s health as “good,” and a record 10 percent rated it as “excellent.” For the first time in the survey’s history, no one rated it as “poor.” While somewhat more muted than sentiments toward the national economy, confidence in the NJ economy is nonetheless surging. 42 percent of respondents rated New Jersey’s economic health as “good” in 2018, compared to 15 percent in 2016. Still, 2018 marks the eighth consecutive year in which no respondent has rated New Jersey’s economy as “excellent.”Survey conducted for New Jersey Bankers Association by Edward J. Bloustein School of Planning and Public Policy. Field period: February 26-April 20, 2018. Published May, 2018
MARC 21 para recursos contínuos
No full textTranslation and adaptation of the MARC 21 Format for Bibliographic Data, and MARC 21 Format for Holdings Data, Network Development and MARC Standards Office, Library of Congress, USA, by Angela Salles. Rio de Janeiro, 2010. 2 v. V.1 MARC 21 format for bibliographic data (updated until October 2010). V.2 MARC 21 format for data collection (Holdings) (updated until October 2008)
MARC 21 para recursos contínuos.
No full textTradução e adaptação de MARC 21 Format for Bibliographic Data e MARC 21 Format for Holdings Data, da Network Development and MARC Standards Office, da Library of Congress, USA, por Angela Salles
Commentary on Bamat et al
No full textSaad, ED (corresponding author), Int Inst Drug Dev, Ave Prov 3, Louvain La Neuve, Belgium.
[email protected]
Metadata initiatives and emerging technologies to improve resource discovery
No full textThis paper discusses some emerging issues on metadata as a mechanism of resource discovery and its impact on precision of search results in a distributed network environment. It presents a brief account of the recent major developments related to metadata across the globe. Highlights a consistent growth of multiple metadata standards to meet the variety of needs in a hierarchy of complexity. Examines various metadata-harvesting tools and related technologies that fulfill the task implicit in a user’s search. Brings out popular standards, useful protocols, and open-source harvesters along with their intrinsic capabilities for harvesting and presenting metadata and introduces a variety of metadata services viz., OCLC’s catalogue service, UKOLN metadata editor service, OAIster harvester service, DP9 gateway service, etc. explores the underlying principles of metadata-harvesting in DSpace and web search engines. Discusses use of multiple metadata formats in DSpace archives for exposing domain-specific metadata; and the inherent mechanism for extensibility and interoperability functions. Proposes methods for creating metadata that can pursue high-precision document retrieval in dynamic collections. Also discuses semantic web technologies and use of specialized metadata for long-term management and preservation of digital objects
Marc Bloch et Lucien Febvre face à l'Allemagne nazie
No full textMarc Bloch and Lucien Febvre in the face of Nazi Germany Contrary to a widespread preconception, the Annales of Marc Bloch and Lucien Febvre were not «unaware» of Nazism, but attempted to explain its genesis and particularities in a number of articles. Thus, in discussing the work of L. Varga, Febvre proposed to analyze Nazism as a socio-cultural movement and not as a doctrine. During the war, the editors of the Annales were directly confronted with the yoke of Nazism in the form of the terrible choice between discontinuing or continuing to publish the revue. Whereas several commentators have recently accused Febvre of «accommodating» or even «collaborating» with the occupying regime, the author reconstitutes the facts involved in the conflict between Bloch and Febvre, arguing in favour of a more impartial understanding of the latter's behaviour.■ Peter Schöttler : Marc Bloch et Lucien Febvre face à l'Allemagne nazie Contrairement à un préjugé répandu, les Annales de Marc Bloch et de Lucien Febvre n'ont pas «ignoré» le nazisme, mais tenté d'expliquer dans de nombreux articles sa genèse et ses particularités. Ainsi, reprenant les travaux de L. Varga, Febvre proposa d'analyser le nazisme termes de mouvement socio-culturel non de doctrine. Durant la guerre, directeurs des Annales furent de façon directe au joug nazi : arrêter continuer la revue, telle fut la alternative dont ils durent débattre. Tandis que plusieurs commentateurs récemment accusé Febvre d'«accomodation», voire même de avec le régime d'occupation, reconstitue les conditions concrètes conflit entre Bloch et Febvre et pour une compréhension plus du comportement de ce dernier.Schöttler Peter. Marc Bloch et Lucien Febvre face à l'Allemagne nazie. In: Genèses, 21, 1995. Le nazisme et les savants, sous la direction de Susanna Magri . pp. 75-95
- …
