67 research outputs found
Coloidal Nanoparticles in Biotechnology
No full textwww.wiley.com/chemistryLearn to use colloidal nanoparticles in a broad range of biotechnology applications Discover new and emerging applications of colloidal nanoparticles. Dr. Abdelhamid Elaissari, internationally respected author and researcher, reports on and analyzes a broad range of important findings from new studies on the use of colloidal nanoparticles in biomedical, food, and environmental diagnostics and analyses. Throughout the presentation, the book uses a blend of classical tools, including optical microscopy, atomic force microscopy, microsystems, and microfluidics, to help you take full advantage of colloidal nanoparticles for your own research and applications. Among the key topics covered are: • The evolution in malaria disease detection, from parasite visualization to colloidal-based rapid diagnostics • Biospecific reactions by affinity latexes, from diagnostics to multiplex assay • Fluorescent colloidal particles as detection tools in biotechnology systems • Gas sensors based on ultrathin films of conducting polymers and nanocomposites • Force measurements between emulsion droplets as a new tool for medical diagnostics • Electrical detection of antibodies from human serum based on the insertion of gold- labeled secondary antibodies into microgaps and nanogaps Special attention is given to the use of particles and reactive particles for in vitro biomedical diagnostics. In addition, the book explores many unusual nanoparticles with interesting and helpful applications. Biotechnological systems are presented and illustrated using examples of actual applications, helping you progress from theory to application. The first book to present and analyze the great potential of colloidal nanoparticles across a broad range of biotechnology applications, this guide will give you the information you need to develop your own important applications and help you to harness these particles' full potential. ABDELHAMID ELAISSARI, PHD, DEA, is Director of Research at the National Center for Scientific Research (CNRS) in Lyon, France. A partial list of his current research interests includes functionalization of complex colloidal systems, physical chemistry and colloidal characterization of colloidal particles, adsorption, desorption, covalent grafting, and specific immobilization of biomolecules and polyelectrolytes onto colloidal particles
Isolation and identification of marine microbial products
No full textAbstract Background The ocean is one of the world’s most important sources of bioactive chemicals in the marine environment. Microbiologists, ecologists, agronomists, taxonomists, and evolutionary biologists have been increasingly interested in marine microbial natural products (MMNPs) in recent decades. Main body Diverse marine bacteria appear to get the ability to manufacture an astounding diversity of MMNPs with a wide range of biological actions, including anti-tumor, antimicrobial, and anti-cardiovascular agents according to numerous studies. Short conclusions Innovative isolation and culture methodologies, tactics for identifying novel MMNPs via routine screens, metagenomics, genomics, combinatorial biosynthesis, and synthetic biology are all discussed in this review. There is also a discussion of potential issues and future directions for studying MMNPs
Nicaraven induces programmed cell death by distinct mechanisms according to the expression levels of Bcl-2 and poly (ADP-ribose) glycohydrolase in cancer cells
No full textNagasaki University (長崎大学)博士(医学)The PARP-1 expression level and poly (ADP-ribosyl)ation activity in cancer markedly affect the therapeutic outcome. Nicaraven, a free radical scavenger has been found to inhibit PARP, but the effect on cancer cells is still unclear. In this study, we investigated the potential role and molecular mechanism of nicaraven on cancer cells. Using U937 lymphoma cells and HCT-8 colorectal cancer cells, we found that nicaraven moderately reduced the cell viability of both cells in a dose-dependent manner. Interestingly, nicaraven significantly induced apoptosis of U937 cells that are dominantly expressing Bcl-2 but induced PAR-dependent cell death (parthanatos) of HCT-8 cells that are highly expressing poly (ADP-ribose) glycohydrolase (PARG). Based on our data, nicaraven seems to induce programmed cell death through distinct mechanisms, according to the expression levels of Bcl-2 and PARG in cancer cells.長崎大学学位論文 学位記番号:博(医歯薬)甲第1528号 学位授与年月日:令和5年3月20日Author: Lina Abdelghany, Tsuyoshi Kawabata, Shinji Goto, Keiichi Jingu, Tao-Sheng LiCitation: Translational Oncology, 26, art. no. 101548; 2022Nagasaki University (長崎大学), 博士(医学) (2023-03-20)doctoral thesi
Biomimicy Approach Design of Petrol Stations with Integrating Renewable Energy in the UAE
No full textHighway petrol stations are located outside the main cities in the UAE. Connecting these remote petrol stations to power plants requires trenching for poles or underground cables as well as countless hours of work. The integration of PV solar panels and smart materials such as chromogenic glazing into the design and structure reduces the cost and the environmental impact. Even though solar energy is one of the cheapest sources of energy worldwide, it is challenging to achieve a design that reflects the identity of the city. Modern technology makes it difficult for designers and architects to balance themes such as sustainability, formation, and identity. The goal of the research is to explore the potential of using smart technologies to improve performance and to demonstrate, simultaneously, the most suitable design for optimizing energy for highway petrol stations in the UAE. As an example, the national Ghaf tree of the UAE is a cultural and historical symbol of stability and peace that can withstand harsh environment. This study introduces a reference design for the petrol station. A three-dimensional model using Autodesk Revit and an energy model using the Autodesk Insight program is built for the reference case. Several designs for the petrol station with different surface areas, shape, orientation, and window-to-wall ratio are studied to optimize the energy consumption. Variables such as the location of the oasis, its area, and its services will remain constant. The study concludes that the dynamic characteristics of smart glazing materials can combine not only one objective sustainable design quality, but more than one, including energy efficiency requirements to harmoniously integrate with the surrounding environmentHeritage & Technolog
Optimization of culture conditions for biodiesel production from Egyptian isolate Penicillium commune NRC2016
No full textAbstract Background Biodiesel is a type of renewable energy, an ideal substitute for petroleum diesel fuel. The present study concerns about optimization of culture conditions for biodiesel production by Penicillium commune NRC2016. Results The maximum lipid production from P. commune NRC2016 was investigated using basal liquid medium with initial pH 7.0, incubation temperature 20 °C, and after 5 days of incubation time at static condition. Six types of agro-industrial by-products (broken rice, rice straw, wheat bran, corn stalk, sweet sorghum, and bagasse) were separately used as components of semi-solid fermentation media. The highest lipid accumulation was recorded with sweet sorghum 99.1 mg/g as compared with the other by-products. Biodiesel obtained from P. commune NRC2016 was blended “B5” and the physical properties were determined and found to be as follows: density 0.8 g/ml, viscosity 2.1 mm2/s, flash point 77.0 °C, cloud point − 1.5 °C, iodine value 42.3 g I2/100 g, acid value 2.1 mg/g, pour point − 1.7 °C, and cetane number 47.8 min. Conclusions This work revealed the optimization of culture conditions for biodiesel production from Egyptian fungal strain P. commune NRC2016
Eco-conscious upcycling of sugarcane bagasse into flexible polyurethane foam for mechanical & acoustic relevance
No full textThis study explores the use of sugarcane bagasse (SCB), a byproduct of sugarcane processing, as a bio-filler in the production of flexible polyurethane foam (FPU), focusing on its benefits for both the environment and the economy. By varying the inclusion of SCB waste from 1 to 6 wt%, the research aims to enhance the FPU's mechanical and acoustic characteristics. Techniques such as Fourier transform infrared (FTIR) spectroscopy and field emission scanning electron microscopy (FESEM) were utilized to analyze the chemical structure and surface characteristics of both SCB and the FPU/SCB composites. Additionally, tests on gel fraction, density, and mechanical properties were conducted. The results indicate that adding 4 wt% SCB to FPU considerably improved the foam's properties. This modification resulted in a 148.63% increase in apparent density, a 228.47% rise in compressive strength, and a 116.24% boost in tensile strength. Furthermore, sound absorption across various frequency ranges was enhanced compared to the control foam. Additionally, the findings show that SCB effectively shifts sound absorption characteristics to lower frequencies. Specifically, at a low frequency of 500 Hz, the sound absorption coefficient increased to 0.4 with a foam thickness of 20 mm. This demonstrates that SCB can significantly improve FPU's performance, making it an attractive option for applications requiring noise mitigation, such as in the automotive and construction industries, thereby offering a sustainable solution to waste management and materials innovation.This article is published as El-Metwaly, Esraa A., Hadeel E. Mohamed, Tarek M. El-Basheer, Manal TH Moselhy, Sonia Zulfiqar, Eric W. Cochran, and Ahmed Abdelhamid Maamoun. "Eco-conscious upcycling of sugarcane bagasse into flexible polyurethane foam for mechanical & acoustic relevance." RSC advances 14, no. 33 (2024): 23683-23692.
doi: https://doi.org/10.1039/D4RA04025B. © 2024 The Author(s). This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence
ICT in Education: A Study of Public Health Education
No full textModern technologies such as Information Communication Technologies have helped many of the development sectors. One of the sectors it has lot of scope to develop is the Education. It is also evident from the experience that the benefits of these technologies have contributed much in the area of healthcare. However, these benefits come with few limitations. A technology is useful only if (a) the systems are designed keeping the user perspective mind, (b) if the users are trained on those systems, (c) users recognize the need for a system and (d) users feel there is a need for such system. Developing a system for an application does not necessarily lead to usage. Many developments ended without giving any benefit to society. For the better usage and the benefits, one has to have a commitment to promote the system among the appropriate users by demonstrating the benefits of such systems. This further discouraged by the restrictions imposed by the IPR regime. There is some relief now due to the popularization of the free software movements. This paper is an effort to highlight the benefits of such systems in public health education with special reference to the open source online tools. Author is a faculty of a Public Health school teaching health management course to the students of public health. The paper addresses the importance of ICT systems in training the public health professionals. It also discusses the benefits and limitations of such system. The present system is a complementary teaching method to the existing classroom teaching.ICT Education, Online Tools, Learning Management System
Electrochemical studies on functional materials derived from biomolecules with potential therapeutic and diagnostic applications
No full textThis thesis was scanned from the print manuscript for digital preservation and is copyright the author.
Researchers can access this thesis by asking their local university, institution or public library to
make a request on their behalf. Monash staff and postgraduate students can use the link in the References field
Designing of a SAW RFID/Sensor Interrogator System
No full textThe purpose of this report is to provide a brief idea about the final year project of the author and the progress achieved so far. The project aims to design a SAW RFID interrogator system on a lab scale, that interrogator would ideally be able to identify each of the SAW tags in its range. The project requires the combination of different scopes of fields such as wireless communication, signal processing and embedded systems. In pursuit of these objectives, extensive research was carried out to find the proposed solutions by previous researchers. System simulation was used to assist in choosing the appropriate solution. This is followed by the design stage where the actual prototype is produced. The next stage is prototype testing and performance assessment. The project is now in the final stages, and should be completed in the few coming days
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