157 research outputs found
sj-docx-1-pie-10.1177_09544089221112071 - Supplemental material for Empirical modeling and optimization of kerf characteristics in Nd-YAG laser cutting of Al 6061-T6 sheet
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089221112071 for Empirical modeling and optimization of kerf characteristics in Nd-YAG laser cutting of Al 6061-T6 sheet by Amit Sharma, Priyanka Joshi and Kuldeep K Saxena in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-1-pie-10.1177_09544089221150740 - Supplemental material for A role of biomaterials in tissue engineering and drug encapsulation
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089221150740 for A role of biomaterials in tissue engineering and drug encapsulation by Reeya Agrawal, Sangeeta Singh, Kuldeep K. Saxena and Dharam Buddhi in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-zip-1-pie-10.1177_09544089221112848 - Supplemental material for Microstructure and texture evolution during the groove rolling of cast aluminum/carbon nanotube composites
No full textSupplemental material, sj-zip-1-pie-10.1177_09544089221112848 for Microstructure and texture evolution during the groove rolling of cast aluminum/carbon nanotube composites by Niraj Nayan, R Madhavan, Kuldeep K Saxena, SVS Narayana Murty and SR Bakshi in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-1-pie-10.1177_09544089231215200 - Supplemental material for Life cycle assessment study on glove box assembly of Indian passenger vehicles
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089231215200 for Life cycle assessment study on glove box assembly of Indian passenger vehicles by Sreeram Jujjavarapu, Srinivas Kota, Nitin R Kotkunde, Naga Vamsi Krishna Jasti and Kuldeep K Saxena in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-1-pie-10.1177_09544089231207421 - Supplemental material for Analytical modelling of a multifunctional heterogeneous beam-bending analysis
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089231207421 for Analytical modelling of a multifunctional heterogeneous beam-bending analysis by Narayanan Kannaiyan Geetha, Pappula Bridjesh, Balram Yelamasetti, Kuldeep K Saxena and Nakul Gupta in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-1-pie-10.1177_09544089221101370 - Supplemental material for Influence of processing and microstructure on the corrosion behavior of ultrafine grained Al 5083 alloy
No full textSupplemental material, sj-docx-1-pie-10.1177_09544089221101370 for Influence of processing and
microstructure on the corrosion
behavior of ultrafine grained
Al 5083 alloy by Dharmendra Singh, Palukuri Nageswara Rao and
Chandra Shekhar Rajoria, Jaiprakash Bhamu, Sunkulp Goel,
Sunil J Raykar, Kuldeep K Saxena, Rangaswamy Jayaganthan in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
sj-docx-2-pie-10.1177_09544089221101370 - Supplemental material for Influence of processing and microstructure on the corrosion behavior of ultrafine grained Al 5083 alloy
No full textSupplemental material, sj-docx-2-pie-10.1177_09544089221101370 for Influence of processing and
microstructure on the corrosion
behavior of ultrafine grained
Al 5083 alloy by Dharmendra Singh, Palukuri Nageswara Rao and
Chandra Shekhar Rajoria, Jaiprakash Bhamu, Sunkulp Goel,
Sunil J Raykar, Kuldeep K Saxena, Rangaswamy Jayaganthan in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
Atomic and Near-atomic Scale Additive Manufacturing: Past, Present, and Future Outlook
No full textThe next stage of micro manufacturing is nano and atomic scale manufacturing. A state-of-the-art approach to manufacturing, atomic and near-atomic scale additive manufacturing (ACSM) seeks to manipulate materials at the atomic or near-atomic level to produce next-generation goods with previously unheard-of precision. Currently, facility for manufacturing and machining at nano and atomic scale is in developing stage, the technique used in the atomic force microscope giving a positive hope to develop a facility for machining a material or deposited a material. The historical evolution from craft-based manufacturing (millimetre precision) and precision-controllable manufacturing (micrometre to nanometre accuracy) to atomic-scale precision is built upon by this field, which is frequently referred to as Manufacturing III. An outline of ACSM is provided here, with an emphasis on current advancements, methods, uses, and difficulties, especially about additive manufacturing. The ACSM is a next stage of industrial revolution
Challenges and Opportunities in Additive Manufacturing in Defence Applications
No full textIn recent years, Additive Manufacturing (AM) has gained significant attention due to its versatility and low-waste production cycle. Additive manufacturing fabricates complex, intricated structures and miniaturized shapes with high dimensional accuracy, tailored properties, multiple materials in a single part, and colour aesthetics. many solid-state and liquid-state AM techniques are available to achieve specific mechanical properties while simultaneously providing thermal and structural stability. Powder bed fusion (PBF) and direct energy deposition (DED) have the potential to make components for the defence and industrial sectors. The part production speed with AM techniques limits the application in mass production. The process involved in this technique is limited to polymers and non-metals for processing, and defects due to the liquid-solid interface need a lot of research to be done. The proposed chapter describes the role of AM in the defence sector and the challenges involved
Fragment-based design, docking, synthesis, biological evaluation and structure–activity relationships of 2-benzo/benzisothiazolimino–5–aryliden–4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors
Get PDFBalanced modulation of several targets is one of the current strategies for the treatment of multi-factorial diseases. Based on the knowledge of inflammation mechanisms, it was inferred that the balanced inhibition of cyclooxygenase-1/cyclooxygenase-2/lipoxygenase might be a promising approach for treatment of such a multifactorial disease state as inflammation. Detection of fragments responsible for interaction with enzyme's binding site provides the basis for designing new molecules with increased affinity and selectivity. A new chemoinformatics approach was proposed and applied to create a fragment library that was used to design novel inhibitors of cycloxygenase-1/cycloxygenase-2/ lipoxygenase enzymes. Potential binding sites were elucidated by docking. Synthesis of novel compounds, and the in vitro/in vivo biological testing confirmed the results of computational studies. The benzothiazolyl moiety was proved to be of great significance for developing more potent inhibitor
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