204 research outputs found
Fully stabilized 750-MHz Yb: fiber frequency comb
This study focuses on presenting a fully stabilized, self-referenced Yb: fiber frequency comb respectively phase locked to a microwave standard and an optical reference employing the highest, fundamental repetition rate of 750-MHz without additional external amplifiers and compressors. In addition, the challenge of phase locking the carrier envelop offset frequency for this high-repetition-rate fiber frequency comb is separately investigated in two schemes, namely, f-2f self-referencing and an approach of phase locking a beat note between the Yb: fiber frequency comb and a continuous wave laser. (C) 2017 Optical Society of AmericaJapan Science and Technology Agency (JST) through the ERATO MINOSHIMA Intelligent Optical Synthesizer (IOS) Project [JPMJER1304]SCI(E)ARTICLE1011910-119182
Department of Radiology Residents (2014-2015)
Residents group photograph, Department of Radiology, 2014-2015. Back Row Left to Right: Michael Bayona; Nik Damme; RJ WIllmore; Jeffrey Tutman; Doug Rogers; Brett Sjoberg; Brad Wright; Booth Aldred; Kaerli Christensen; Zachary Smith. Middle Row Left to Right: Ben Morrissey; Elaine Pigman; Bryn Putbrese; Justin Kaptuch; Atul Mallik; Kevin Horn; Satoshi Minoshima; Laura Eisenmenger. Front Row Left to Right: Leif Jensen; Michael McLaughlin; Loren Longenecker; Megan Mills; Reza Pakdaman; Marta Heilbrun
Department of Radiology Residents (2018-2019)
Residents group photograph, Department of Radiology, 2018-2019. Back Row Left to Right: Caleb Sturge; Brittany Morgan; Michael Wintraub; Adriene Eastaway; Samuel Wilhite; Abby Cogman; Tyler Smith. Middle Row Left to Right: Soham Banerjee; Matthew Curtis; April Griffith; Katie Totino; Jill Fadal; Samuel Braden. Middle Row Left to Right: Nathan Kwok; Justin Costello; Laura Linstroth; Zachary Berg; Elizabeth Ryals. Front Row Left to Right: Jessica Chan; Nicole Winkler; Leif Jensen; Satoshi Minoshima; Megan Mills; Elizabeth Joiner; Geoffry deGennaro
Department of Radiology Residents (2016-2017)
Residents group photograph, Department of Radiology, 2016-2017. Back Row Left to Right: Douglas Rogers; Adam Binneboese; Peter Hinckley; Jeffrey Tutman; Geoff deGennaro; Elizabeth Joiner; Caleb Sturge; Laura Linstroth. Middle Row Left to Right: Samuel Braden; Elaine Pigman; Tanner Clark; Jessica Chan; Bryn Putbrese; Michael Bayona; Katie Totino; Elizabeth Ryals. Front Row Left to Right: Satoshi Minoshima; Laura Eisenmenger; Kaerli Christensen; Scott Parker; Ben Morrissey; Nik Damme; Leif Jensen; Marta Heilbrun
Department of Radiology Residents (2015-2016)
Residents group photograph, Department of Radiology, 2015-2016. Back Row Left to Right: Geoff deGennaro; Atul Mallik; Zach Smith; Nik Damme; Roderick J. Willmore; Zachary Berg; Douglas Rogers; Elaine Pigman; Kaeli Christensen; Bryn Putbrese; Elizabeth Ryals. Middle Row Left to RIght: Brett Sjoberg; Jessica Chan; Michael Bayona; Oliver Edwards; Jeffrey Tutman; Laura Lynch; Laura Eisenmenger; Elizabeth Joiner. Front Row Left to Right: Leif Jensen; Scott Parker; Ben Morrissey; Satoshi Minoshima; Michael McLaughlin; Loren Longenecker; Marta Heilbrun
Cerebral processing of acute skin and muscle pain in humans
Svensson, Peter, Satoshi Minoshima, Ahmad Beydoun, Thomas J. Morrow, and Kenneth L. Casey. Cerebral processing of acute skin and muscle pain in humans. J. Neurophysiol. 78: 450–460, 1997. The human cerebral processing of noxious input from skin and muscle was compared with the use of positron emission tomography with intravenous H2 15O to detect changes in regional cerebral blood flow (rCBF) as an indicator of neuronal activity. During each of eight scans, 11 normal subjects rated the intensity of stimuli delivered to the nondominant (left) forearm on a scale ranging from 0 to 100 with 70 as pain threshold. Cutaneous pain was produced with a high-energy CO2 laser stimulator. Muscle pain was elicited with high-intensity intramuscular electrical stimulation. The mean ratings of perceived intensity for innocuous and noxious stimulation were32.6 ± 4.5 (SE) and 78.4 ± 1.7 for cutaneous stimulation and 15.4 ± 4.2 and 73.5 ± 1.4 for intramuscular stimulation. The pain intensity ratings and the differences between noxious and innocuous ratings were similar for cutaneous and intramuscular stimuli ( P > 0.05). After stereotactic registration, statistical pixel-by-pixel summation ( Z score) and volumes-of-interest (VOI) analyses of subtraction images were performed. Significant increases in rCBF to both noxious cutaneous and intramuscular stimulation were found in the contralateral secondary somatosensory cortex (SII) and inferior parietal lobule [Brodmann area (BA) 40]. Comparable levels of rCBF increase were found in the contralateral anterior insular cortex, thalamus, and ipsilateral cerebellum. Noxious cutaneous stimulation caused significant activation in the contralateral lateral prefrontal cortex (BA 10/46) and ipsilateral premotor cortex (BA 4/6). Noxious intramuscular stimulation evoked rCBF increases in the contralateral anterior cingulate cortex (BA 24) and subsignificant responses in the contralateral primary sensorimotor cortex (MI/SI) and lenticular nucleus. These activated cerebral structures may represent those recruited early in nociceptive processing because both forms of stimuli were near pain threshold. Correlation analyses showed a negative relationship between changes in rCBF for thalamus and MI/SI for cutaneous stimulation, and positive relationships between thalamus and anterior insula for both stimulus modalities. Direct statistical comparisons between innocuous cutaneous and intramuscular stimulation with the use of Z scores and VOI analyses showed no reliable differences between these two forms of noxious stimulation, indicating a substantial overlap in brain activation pattern. The comparison of noxious cutaneous and intramuscular stimulation indicated more activation in the premotor cortex, SII, and prefrontal cortex with cutaneous stimulation, but these differences did not reach statistical significance. The similar cerebral activation patterns suggest that the perceived differences between acute skin and muscle pain are mediated by differences in the intensity and temporospatial pattern of neuronal activity within similar sets of forebrain structures. </jats:p
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