50,367 research outputs found
Participació en recerca: per què i com
No full textParticipació del pacient en recerca; Jornada SARIS; PlanificacióParticipación del paciente en investigación; Jornada SARIS; PlanificaciónPatient participation; SARIS; PlanningEn aquest document es presenta un resum de la Jornada SARIS sobre Participació del Pacient en Recerca duta a terme a Barcelona el 4 d’abril de 2018
Sistema d’avaluació de la recerca en salut: avaluació responsable
No full textRecerca sanitària; PERIS; SARISInvestigación sanitaria; PERIS; SARISHealth research; PERIS; SARISEn aquest document es presenta el model d’avaluació de la recerca del sistema d’avaluació de la recerca i innovació en salut (SARIS), sense incloure els aspectes de la innovació. El SARIS és l’instrument estratègic de la Direcció General de Recerca i Innovació en Salut (DGRIS) per al desenvolupament, seguiment i avaluació del Pla estratègic de recerca i innovació en salut (PERIS) 2016-20. L’objectiu primari del SARIS és avaluar la recerca en salut que es promou en el marc del PERIS 2016-2020 durant el seu desplegament. Els objectius secundaris són: 1) retre comptes i 2) millorar l’impacte a través de dos subobjectius (2a, l’anàlisi per millorar i 2b, la implicació –engagement– dels actors en assolir més i millor impacte en salut)
¿Estamos preparados para la participación ciudadana en investigación en salud?
No full textParticipació ciutadana; SARIS; RecercaParticipación ciudadana; SARIS; InvestigaciónCitizen participation; SARIS; ResearchEn aquest document es revisa l’estat de la participació de la ciutadania en el procés de recerca en salut i innovació a través d’una prova pilot amb grups de discussió a dos instituts d’investigació biomèdica: l’IDIBAPS i el VHIR. Es planteja la pregunta: estem preparats per fer participar a la ciutadania en la recerca en salut? Per donar resposta, es revisa el concepte de participació ciutadana, així com els seus beneficis. La discussió amb els professionals posa de manifest que, tot i que es fan avenços, els esforços encara estan molt centrats a informar, i que es desconeixen força les opcions de participació com consultar, implicar o cocrear. D’acord amb els experts, la participació de la ciutadania en la recerca encara està en un estat molt embrionari i, encara que es percep com a quelcom beneficiós, hi ha nombrosos reptes a l’hora de dur-la a la pràctica. Finalment, en base a les aportacions dels professionals, AQuAS exposa 10 recomanacions aplicables a les institucions de recerca en salut de Catalunya que es poden portar a terme per tal de facilitar la participació de la ciutadania en la recerca
Com ha anat el primer PERIS d’infermeria?: anàlisi de l'impacte immediat i directe de la recerca infermera del PERIS 2017
No full textRecerca sanitària; PERIS; InfermeriaInvestigación sanitaria; PERIS; EnfermeríaHealth research; PERIS; NurseryLa convocatòria del PERIS del 2017 ha afavorit, per primera vegada, la intensificació en investigació als professionals infermers i infermeres. Durant un període màxim de nou mesos aquesta intensificació ha permès alliberar aquests professionals de les tasques assistencials per desenvolupar activitats de recerca. El present monogràfic recull una anàlisi sistèmica de l’estat de situació indicant el que ha suposat aquesta convocatòria pel que fa a oportunitats per als professionals intensificats i beneficis per al sistema de salut. Això s’ha fet a través de l’anàlisi de text de les Instantànies de Recerca, unes fitxes que van emplenar els beneficiaris dels ajuts al final del període sobre l’experiència, la recerca, els seus resultats i els beneficis obtinguts. Els beneficis per al sistema i les oportunitats que ha suposat per als 61 professionals intensificats es pot resumir en la generació de coneixement divers i heterogeni que ha impactat tant en l’àmbit assistencial com en l’àmbit de recerca, generant valor, reconeixement i visibilitat a la recerca en infermeria, influència en les actituds dels professionals del seu entorn, reforçant relacions professionals i col·laboracions, creant noves competències formals (tesis doctorals) i informals, interaccions amb els usuaris del coneixement (siguin professionals o altres investigadors) i, en última instància, aplicant els resultats als processos assistencials, a les intervencions sanitàries i als programes. Les oportunitats necessiten, tanmateix, un suport sostingut, sobretot perquè molts dels beneficis que aquí es relaten impliquen un canvi cultural per al col·lectiu de professionals de la salut que no es fa en un, dos o tres anys. És doncs important que aquest camí encetat continuï amb un suport institucional com ja s’està fent i també amb un suport mutu i cooperació entre professionals,que les sessions del SARIS van intentar iniciar i reforçar
Detection of Unlikely Answers in Survey Research
No full textIn recent years a lot of attention has been dedicated to non-sampling survey errors, and many editing procedures have been elaborated. The widespread use of computer-assisted surveys makes it possible to perform on-line checks and corrections, which are particularly useful, because the respondent himself can solve the eventually detected inconsistencies. Most of the editing procedures are limited to detect and correct impossible answers or combinations of answers. This contribution investigates the feasibility of a general automatic on-line procedure to detect not only impossible, but also inconsistent and unlikely answers
Participació en recerca: per què i com
No full textParticipació del pacient en recerca; Jornada SARIS; PlanificacióParticipación del paciente en investigación; Jornada SARIS; PlanificaciónPatient participation; SARIS; PlanningEn aquest document es presenta un resum de la Jornada SARIS sobre Participació del Pacient en Recerca duta a terme a Barcelona el 4 d’abril de 2018
Phage-host interactions in <em>Lactobacillus delbrueckii</em>: host recognition and transcription of early phage genes
No full textAbstractThe scope of this study includes aspects of phage evolution and antagonistic/mutualistic coevolution between a phage and its host. As a basic study it may provide tools for developing phage resistant starters and offer regulatory elements and factors for biotechnological applications.The LL-H anti-receptor was characterized by isolation of spontaneous LL-H host range mutants and subsequent sequencing of candidate genes. All LL-H host range mutants carried a single point mutation at the 3' end of a minor tail protein encoding gene g71. The genomic location of g71 is congruent with the other verified anti-receptor genes found in the λ supergroup. The C-terminus of Gp71 determines the adsorption specificity of phage LL-H similarly for the number of phages infecting Gram-positive and Gram-negative bacteria. A Gp71 homolog of phage JCL1032 showed 62% identity to LL-H Gp71 within the last 300 amino acids at the C-terminus.Lactobacillus delbrueckii phage receptors were investigated by the purification of different cell surface structures. Certain Lb. delbrueckii phages from homology groups a and c including LL-H, LL-H host range mutants and JCL1032, were specifically inactivated by the LTAs. In structural analyses LTAs showed differences in the degree of α-glucosyl and ᴅ-alanyl substitution. α-glucose is necessary for LL-H adsorption. A high level of ᴅ-alanine esters in LTA backbones inhibited Lb. delbrueckii phage inactivation in general. Lysogenization of strain ATCC 15808 with the temperate phage JCL1032 revealed a rarely described coexistence of phage adsorption resistance and phage immunity, which could not be explained by lysogenic conversion. In this case the role of spontaneously induced JCL1032 may be significant.The LL-H early gene region was localized between the dysfunctional lysogeny module and the terminase encoding genes. The function of five ORFs could be connected to phage DNA replication and/or homologous recombination. Transcription of LL-H genes could be divided into two, possibly three, phases in which large gene clusters were sequentially transcribed. The intensity of the late transcripts exceeded the intensity of the early transcripts by several times. Two candidate genes for transcription regulators were found. One of the two candidates is the first ORF in the LL-H early gene region.Academic dissertation to be presented, with the assent of the Faculty of Science of the University of Oulu, for public defence in Kuusamonsali (Auditorium YB210), Linnanmaa, on May 4th, 2007, at 12 noonAbstract
The scope of this study includes aspects of phage evolution and antagonistic/mutualistic coevolution between a phage and its host. As a basic study it may provide tools for developing phage resistant starters and offer regulatory elements and factors for biotechnological applications.
The LL-H anti-receptor was characterized by isolation of spontaneous LL-H host range mutants and subsequent sequencing of candidate genes. All LL-H host range mutants carried a single point mutation at the 3' end of a minor tail protein encoding gene g71. The genomic location of g71 is congruent with the other verified anti-receptor genes found in the λ supergroup. The C-terminus of Gp71 determines the adsorption specificity of phage LL-H similarly for the number of phages infecting Gram-positive and Gram-negative bacteria. A Gp71 homolog of phage JCL1032 showed 62% identity to LL-H Gp71 within the last 300 amino acids at the C-terminus.
Lactobacillus delbrueckii phage receptors were investigated by the purification of different cell surface structures. Certain Lb. delbrueckii phages from homology groups a and c including LL-H, LL-H host range mutants and JCL1032, were specifically inactivated by the LTAs. In structural analyses LTAs showed differences in the degree of α-glucosyl and ᴅ-alanyl substitution. α-glucose is necessary for LL-H adsorption. A high level of ᴅ-alanine esters in LTA backbones inhibited Lb. delbrueckii phage inactivation in general. Lysogenization of strain ATCC 15808 with the temperate phage JCL1032 revealed a rarely described coexistence of phage adsorption resistance and phage immunity, which could not be explained by lysogenic conversion. In this case the role of spontaneously induced JCL1032 may be significant.
The LL-H early gene region was localized between the dysfunctional lysogeny module and the terminase encoding genes. The function of five ORFs could be connected to phage DNA replication and/or homologous recombination. Transcription of LL-H genes could be divided into two, possibly three, phases in which large gene clusters were sequentially transcribed. The intensity of the late transcripts exceeded the intensity of the early transcripts by several times. Two candidate genes for transcription regulators were found. One of the two candidates is the first ORF in the LL-H early gene region
Author Self-Citation in the Turkish Otorhinolaryngology Literature
No full textObjective:To evaluate the prevalence and other characteristics of author self-citations in six Turkey-originated general otorhinolaryngology (ORL) journals of Turkish ORL literature.Methods:A total of 970 articles published in six Turkey-originated general ORL journals (ENT Updates, Journal of Ear Nose Throat and Head Neck Surgery, KBB-Forum, Praxis of Otorhinolaryngology, The Turkish Journal of Ear Nose and Throat, and Turkish Archives of Otorhinolaryngology) in 2016-2020 were analyzed for author self-citations. The association between author self-citations and journal types, study types, study topics, country of origin, and compatibility with the topic were also evaluated.Results:There were 265 author self-citations (0.273 per article) which corresponded to 1.36% of all citations. There was no significant difference between the journal types, study topics, and origin of the studies in terms of mean self-citation values per study, whereas case reports had significantly lower self-citations than review and original investigations. There were three citations (1.1%) that were irrelevant to the study topic.Conclusion:To the best of our knowledge, this is the first study that investigated the practice of author self-citation in Turkish ORL literature. Author self-citation rate in the Turkish-originated general ORL journals was found remarkably lower than the medical literature, whereas the self-citations were found compatible with the study topic to a very large extent. Members of the scientific community including authors, readers, and journal editors should be cautious regarding the unethical practices of self-citations
Applicativo web per audioguide - HooRMI Author
No full textHooRMI Author è la parte da content creator del progetto HooRMI.
La dissertazione si concentra sul funzionamento HooRMI Author, ovvero di come viene permesso all'utente di produrre contenuti video basati sulla propria posizione acquisita tramite tecnologia Plus code e caricarli sul proprio canale Youtube. I contenuti risulteranno pronti per essere selezionati e fruiti dai turisti, grazie alla profonda personalizzazione dei metadati associati ad ogni clip
Sectoral allocation by gender of Latin American workers over the liberalization period of the 1990s
No full textThe recent restructuring of Latin American economies has renewed interest in the effects of trade liberalization, on labor markets, and on the gender division of labor. The author does not attempt to establish casuality between economic reforms, and the types of jobs that men and women hold. Instead, she provides a detailed description of the trends in male, and female formal, and informal sector participation during the economic reform period in Argentina, Brazil, and Costa Rica. The author first compares the gender composition of the formal, informal wage, and self-employment sectors in a year before reforms (1988 for Argentina, 1989 for Brazil, and Costa Rica), and a year after reforms implementation (1997 for Argentina, 1995 for Brazil and Costa Rica). Although women continued to be more likely than men to work in the informal wage sector, there is no trend of"masculinization"or"feminization"of the informal sector, or any other. Instead, in Argentina men have overtaken women as the most prevalent workers in the informal wage sector, while in Brazil, the opposite has occurred (as men move into self-employment). In Costa Rica there have been no statistical, observable changes. The author then considers the distribution across sectors within each gender group, to identify whether men, and women are more likely to select different sectors in the post-reform period relative to the pre-reform period. Among both men, and women in all three countries (except Brazilian men), workers have become more likely to hold informal wage jobs, and less likely to hold formal sector jobs. Trends in human capital accumulation explain these changes for both men, and women, while changes in gender roles, primarily in homecare and marriage, do not seem to have an effect.Health Monitoring&Evaluation,Labor Policies,Population&Development,Public Health Promotion,Environmental Economics&Policies,Health Monitoring&Evaluation,Environmental Economics&Policies,Population&Development,Banks&Banking Reform,Work&Working Conditions
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