1,720,968 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Towards a better understanding of xylanase inhibition by taxi-type proteins: a crystallographic study
Get PDFDe afbraak van plantaardig celwandmateriaal door middel van enzymen is b elangrijk in verschillende biologische processen. Ten eerste is het enzy matisch moduleren van de celwand een vereiste tijdens groei- en andere o ntwikkelingsstadia van planten. Daarnaast produceren tal van micro-organ ismen een ganse waaier van afbraakenzymen, die hen in staat moeten stell en een plant binnen te dringen. Tenslotte vormt de enzymatische depolyme risatie een sleutelproces in veel industriële toepassingen, alsook in de natuurlijke recyclage van organisch materiaal. De belangrijkste hemicellulose component in de complexe celwandmatrix va n graangewassen is de heteroxylanfractie die voornamelijk uit arabinoxyl anen bestaat. Endo-ß-1,4-xylanasen, de enzymen die het verbre ken van de suikerverbindingen in de (arabino)xylan-ketenstructuur kataly seren, kunnen daarom beschouwd worden als de xylanolytische enzymen met de grootste impact op zowel biologische als biotechnologische processen. In 1997 werd aan het Laboratorium voor Levensmiddelenchemie van de K.U. Leuven voor het eerst vastgesteld dat in graangewassen eiwitten aanwezig zijn die de normale werking van xylanasen verhinderen. Wat later slaagd e men erin een eerste type eiwitten met xylanase-inhiberende werking op te zuiveren uit graan (Triticum aestivum L.). Deze werden, verwijz end naar hun oorsprong, TAXIs (Triticum aestivum xylanase inhibito r) genoemd. In dit onderzoek werd proteïnekristallografie aangewend:&nbs p;i) om inzicht te verwerven in de driedimensionale structuur van deze recent ontdekte familie TAXI-type inhibitoren; ii) om zi cht te krijgen op de moleculaire interactie tussen xylanasen en TAXIs; e n iii) om de ruimtelijke structuur te bepalen van een gemodif iceerd xylanase dat niet langer door TAXIs wordt geïnhibeerd. Nauwkeurige structuren van TAXI-IA en TAXI-IIB, en structuren van TAXI-I A in complex met A. niger xylanase, TAXI-IA in complex met&nb sp;B. subtilis xylanase en TAXI-IIA geassocieerd met B. su btilis xylanase konden worden bepaald. Daarnaast werd de structuur va n een niet-geïnhibeerde B. subtilis xylanase mutant opgehelde rd, beide in vrije en ligand-gebonden toestand. De bevind ingen dat TAXIs in planten defensief kunnen optreden door het verhindere n van de afbraak van de celwandmatrix door microbiële xylanasen, samen m et het moleculaire inzicht bekomen met de drie modellen van TAXI·xy lanase complexen en resultaten van genetische en biochemische karakteris atie, laten toe om de fysiologische functie van xylanase activiteit en i nhibitie bij planten te evalueren. Binnen een pathogeen-gastheer relatie beïvloeden pathogeniciteit en resistentie elkaar door direkte interacti es tussen eiwitten van beide partijen. Een dergelijke wisselwerking vorm t de ideale voedingsbodem voor een moleculaire co-evolutie van de virule ntie en resistentie genen, die snel gaan diversifiëren met de kans een n ieuwe specificiteit te ontwikkelen. Voor de aminozuren betrokken in de T AXI-xylanase interactie kan inderdaad een voorgeschiedenis van positieve selectie en een aanpassend vermogen aangetoond worden. Een opbiedende w apenwedloop waarbij enerzijds pathogene micro-organismes meerdere xylana sen met een verschillende vatbaarheid tegenover TAXIs produceren en ande rzijds TAXIs zich aanpassen teneinde zoveel mogelijk xylanasen te inhibe ren, is bovendien perfect in overeenstemming te brengen met de criteria voor TAXI-specificiteit die we konden afleiden uit de bekomen structurel e informatie. De grondige kennis van de TAXI-xylanase wisselwerking die met dit onderzoek gegenereerd werd, samen met moleculair genetische tech nieken, laat toe om milieubelastende klassieke chemische processen te ve rvangen door de natuurlijke werking van recombinant aangemaakte gemodifi ceerde enzymen. Daarnaast vormt het inzicht in de TAXI·xylanase int eractie een goede basis om te screenen voor natuurlijk voorkomende xylan asen en/of inhibitoren die een groot potentieel in zich dragen om aan ee n welbepaald vatbaarheids- of specificiteitsprofiel te beantwoorden.status: Publishe
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
- …
