1,721,134 research outputs found

    Biofisica e tissue engineering

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    Campi elettromagnetici pulsati in ortopedia e traumatologi

    Biomechanics of the natural, arthritic, and replaced human ankle joint

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    The human ankle joint complex plays a fundamental role in gait and other activities of daily living. At the same time, it is a very complicated anatomical system but the large literature of experimental and modelling studies has not fully described the coupled joint motion, position and orientation of the joint axis of rotation, stress and strain in the ligaments and their role in guiding and stabilizing joint motion, conformity and congruence of the articular surfaces, patterns of contact at the articular surfaces, patterns of rolling and sliding at the joint surfaces, and muscle lever arm lengths. The present review article addresses these issues as described in the literature, reporting the most recent relevant finding

    Gait analysis with a multi-segment foot model for the biomechanical validation of hinged foot-ankle orthoses

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    Hinged Ankle Foot Orthoses (HAFO) are largely prescribed for the treatment of ankle joint deficits, within a variety of neurological and orthopedic disorders. These are intended to control motion of this joint, to compensate for weakness, to correct deformities or to reduce mobility in the sagittal plane only. Quantitative assessment of their functional efficacy is still very limited. The aim of this study is to assess by means of state-of-the-art gait analysis the effect of the position of the mechanical axis of rotation in unlocked HAFO. Unfortunately, in routine custom-made manufacturing, this axis of rotation is positioned exactly mediolaterally, and also a few centimeters above the malleoli, very far from the intermalleolar physiological location.Apossible better axis location for more physiological foot joint rotations was sought by looking at multi-segment foot kinematic

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    How to Treat Cartilage Injuries in the Ankle Joint by BMDC' s Transplantation

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    Osteochondral lesions of the ankle joint are defects of the cartilaginous surface and underlying subchondral bone, typically affecting the talus, most frequently traumatic in origin. Osteochondral lesions are often asymptomatic and may be treated conservatively, taking care to follow the patient over time. Bigger lesions, or higher grade lesions, especially in adult patients, are usually painful and hardly respond to a conservative treatment. So(( that,)) surgical treatment is frequently indicated. Thanks to technical advancements, regenerative techniques are quickly moving from traditional periostium based autologous chondrocyte implantation (ACI) to bone marrow derived cell transplantation (BMDCT). The introduction of a biodegradable scaffold based on the benzylic ester of hyaluronic acid for cell support and proliferation represented a first advancement toward a full arthroscopic procedure and significatively decreased the morbidity of ACI procedure in the ankle joint. Still two surgeries were required. Recently, BMDCT has been proposed as a technique capable to provide a repair of the lesion by hyaline cartilage in a one step procedure. Mesenchymal stem cells have the ability to differentiate into osteoblasts and chondroblasts. The rationale of the “one-step technique” is to transplant the entire bone-marrow cellular pool instead of isolated and expanded mesenchymal stem cells. This allows cells to be processed directly in the operating room, without the need for a laboratory phase, and BMDCT to be performed in “one step”. With a dedicated kit a total amount of about 60 ml of bone marrow aspirate is harvested from the posterior iliac crest, with the patient in prone decubitus. A scaffold and the instrumentation previously used for ACI are then used for an entirely arthroscopic implantation. Autologous platelet-rich fibrin (PRF) is added in order to provide a supplement of growth factors. The results of this procedure have been confirmed by biopsies and T2 mapping MRI and are clinically encouraging at mid-term. Evolution in surgical technique, new biomaterials and more recently the use of BMDCs permitted a marked reduction in procedure morbidity and costs up to a “one step” technique able to overcome the drawbacks of previous repair techniques. The stability of the results needs to be followed long term

    Biomeccanica dell’anca e studio di Gait analysis

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    Biomeccanica dell'anca e studio gait analysis nell'accesso anteriore mini-invasivo nella chirurgia protesica dell'anca
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