1,621 research outputs found

    Micro-scratching behavior of heat-treated cutting chips of Inconel 718

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    The present work investigates the micro-scratching behavior of Inconel 718 alloy processed by machining and subsequent heat-treatment. As-machined chips were heat-treated at 700 °C, 800 °C, and 900 °C, all for a short duration of 15 min, followed by water quenching to allow the precipitation of γ I and γ II phases. Microstructural analysis of the processed Inconel 718 chips revealed the formation of nano-size precipitates either along the grain boundaries or at the triple junctions, which contributed to the improved mechanical property compared to the solution annealed sample. It was found that the chips heat-treated at 700 °C possessed the highest average hardness (548 Kgf/mm 2) among all the sample conditions. High hardness of as-machined chips and short heat-treatment at 700 °C led bimodal microstructure and precipitation pining resulting in maximum wear resistance compared to other heat-treatment conditions. Subsequently, to verify the outcome, worn surface analysis of as-machined and subsequently heat-treated chips was performed. Comparatively, larger size cracks in sample heat-treated at 900 °C attributed to a high cracking scratch zone in the processed material, i.e., less wear resistance, whereas no/nominal crack in as-machined chips and chips heat-treated at 700 °C attributed to no cracking scratch zone. </p

    <b>Supplemental Material - Rituximab as add-on therapy in patients with resistant lupus nephritis who have failed induction or maintenance therapy with other agents: A real-world experience from a single center in Mumbai</b>

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    Supplemental Material for Rituximab as add-on therapy in patients with resistant lupus nephritis who have failed induction or maintenance therapy with other agents: A real-world experience from a single center in Mumbai by Sandeep Yadav, C Balakrishnan, Gurmeet Mangat and Jatin Kothari in Lupus.</p

    First person – Shweta Yadav

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    ABSTRACT First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Shweta Yadav is the first author on ‘RDGBα localization and function at membrane contact sites is regulated by FFAT–VAP interactions’, published in Journal of Cell Science. Shweta is a post-doctoral associate in the laboratory of Prof. Juan Botas at Baylor College of Medicine, Texas, USA, investigating neurodegenerative diseases.</jats:p

    The generation of dual wavelength pulse fiber laser using fiber bragg grating

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    A stable simple generation of dual wavelength pulse fiber laser on experimental method is proposed and demonstrated by using Figure eight circuit diagram. The generation of dual wavelength pulse fiber laser was proposed using fiber Bragg gratings (FBGs) with two different central wavelengths which are 1550 nm and 1560 nm. At 600 mA (27.78 dBm) of laser diode, the stability of dual wavelength pulse fiber laser appears on 1550 nm and 1560 nm with the respective peak powers of -54.03 dBm and -58.00 dBm. The wavelength spacing of the spectrum is about 10 nm while the signal noise to ratio (SNR) for both peaks are about 8.23 dBm and 9.67 dBm. In addition, the repetition rate is 2.878 MHz with corresponding pulse spacing of about 0.5 μs, is recorded

    Comparative genomic analysis reveals evolutionary and structural attributes of MCM gene family in Arabidopsis thaliana and Oryza sativa

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    The mini-chromosome maintenance (MCM) family, a large and functionally diverse protein family belonging to the AAA+ superfamily, is essential for DNA replication in all eukaryotic organisms. The MCM 2-7 form a heterohexameric complex which serves as licensing factor necessary to ensure the proper genomic DNA replication during the S phase of cell cycle. MCM 8-10 are also associated with the DNA replication process though their roles are particularly unclear. In this study, we report an extensive in silico analysis of MCM gene family (MCM 2-10) in Arabidopsis and rice. Comparative analysis of genomic distribution across eukaryotes revealed conservationof core MCMs 2-7 while MCMs 8-10 are absent in some taxa. Domain architecture analysis underlined MCM 2-10 subfamily specific features. Phylogenetic analyses clustered MCMs into 9 clades as per their subfamily. Duplication events are prominent in plant MCM family, however no duplications are observed in Arabidopsis and rice MCMs. Synteny analysis among Arabidopsis thaliana, Oryza sativa, Glycine max and Zea mays MCMs demonstrated orthologous relationships and duplication events. Further, estimation of synonymous and nonsynonymous substitution rates illustrated evolution of MCM family under strong constraints. Expression profiling using available microarray data and qRT-PCR revealed differential expression under various stress conditions, hinting at their potential use to develop stress resilient crops. Homology modeling of Arabidopsis and rice MCM 2-7 and detailed comparison with yeast MCMs identified conservation of eukaryotic specific insertions and extensions as compared to archeal MCMs. Protein-protein interaction analysis revealed an extensive network of putative interacting partners mainly involved in DNA replication and repair. The present study provides novel insights into the MCM family in Arabidopsis and rice and identifies unique features, thus opening new perspectives for further targeted analyses

    The hired farm labor market: some recent evidence from Oregon

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    T.M. Hammonds, R. Yadav, and C. Vathana.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references (pages 22-23).Mode of access: Internet from the Oregon Government Publications Collection.Text in English

    Modern techniques for agricultural disease management and crop yield prediction Advances in environmental engineering and green technologies (AEEGT) book series./ N. Pradeep, Sandeep Kautish, C.R. Nirmala, Vishal Goyal, Sonia Abdellatif, [editors].

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    "eISSN: 2326-9170."Includes compilation of bibliographical references (pages 259-284) and index."This book explores the current practices and widespread open challenges in the field of applications of computational techniques in smart agriculture. It also examines computational methods that will aid in agriculture disease management, weed detection, and crop yield prediction"--Provided by publisher.Issues and challenges in smart farming for sustainable agriculture / Immanuel Zion Ramdinthara, Shanthi Bala P -- Image processing techniques aiding smart agriculture / Aspira S. Tripathy, Deepak Kumar Sharma -- Expert system design for diagnosis of diseases for paddy crop / Sreekantha Desai Karanam, Deepthi M.B. -- Deep learning and computer vision in smart agriculture / Shiv Kumar, Agrima Yadav, Deepak Kumar Sharma -- Computer vision for green plant segmentation and leaf count / Praveen Kumar J., Domnic S. -- Automatic data acquisition and spot disease identification system in plants pathology domain : agricultural intelligence system in plant pathology domain / Rajesh T.M., Kavyashree Dalawai, Pradeep N. -- Applications of data mining techniques in smart farming for sustainable agriculture / Anandhavalli Muniasamy -- Agro guardian : a smart agriculture framework for precision farming / Sanjeevakumar M. Hatture, Susen P. Naik -- A study on technology-LED solution for fruit grading to address post-harvest handling issues of horticultural crops / Arun Kumar R., Vijay S. Rajpurohit, Sandeep Kautish -- Optimized data mining techniques for outlier detection, removal, and management zone delineation for yield prediction / Roopa G.M., Arun Kumar G.H., Naveen Kumar J.R., Nirmala C.R.1 online resource (xix, 291 pages)

    “Discovery of the Wave-Edge Rectangle (WER) and its Area Formula”

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    Title: The Wave-Edge Rectangle (WER): A Newly Identified Geometric Structure and Its Area Formula Author: Yadvendra Singh Yadav Date: 2 December 2025 Summary: I discovered a new geometric shape called the Wave-Edge Rectangle (WER), formed by replacing all four straight sides of a rectangle with equal semicircular arcs. I derived a general area formula: =2(4+(+)

    Distinct intramolecular hydrogen bonding dictates antimicrobial action of membrane-targeting amphiphiles

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    As mechanisms underpinning the molecular interactions between membrane-targeting antimicrobials and Gram-negative bacterial membranes at atomistic scale remain elusive, we used cholic acid (CA)-derived amphiphiles with different hydrophobicities as model antimicrobials and assessed the effect of their conformational flexibility on antimicrobial activity. Relative to other hydrophobic counterparts, a compound with a hexyl chain (6) showed the strongest binding with the lipopolysaccharide (LPS) of Gram-negative bacterial membranes and acted as an effective antimicrobial. Biomolecular simulations, validated by complementary approaches, revealed that specific intramolecular hydrogen bonding imparts conformationally rigid character to compound 6. This conformational stability of compound 6 allows minimum but specific interactions of the amphiphile with LPS that are a sum of exothermic processes like electrostatic interactions, membrane insertion, and endothermic contributions from disaggregation of LPS. Therefore, our study reveals that a membrane-targeting mechanism with the help of conformationally selective molecules offers a roadmap for developing future therapeutics against bacterial infections.</p

    Ultra-light nanocomposite aerogels of bacterial cellulose and reduced graphene oxide for specific absorption and separation of organic liquids

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    Novel materials based on sustainable materials with high absorption capacity are still rare for the separation of organic liquids or oil spills and water. In this report, ultra-light nanocomposite aerogels consisting of sustainable bacterial cellulose (BC) and graphene oxide (GO) were constructed after an eco-friendly freeze-drying process for the first time. Due to the hydrophilic properties of both materials and the highly porous structure, BC/GO aerogels could highly absorb not only organic liquids, such as cyclohexane and DMF, but also water. Specific absorption for organic liquids was achieved after the reduction of GO using H-2 gas, which led to nanocomposite aerogels of BC and reduced GO. They could specifically absorb 135-150 g organic liquids per g of their own weight, even with a high content of 80 BC in the nanocomposite aerogel
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