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Concepts of Health and Disease. Traditions and Misconceptions
No full textThe organization of disease program management requires a radical change in the strategy and tactics of medicine in relation to each patient and the population as a whole. The purpose of the publication is to help doctors understand the dual nature of diseases. The author's task is to provide the necessary methodological tools and acquaint biologists and doctors with the repository of disease programs in the phylogenetic memory of all living beings, including humans. Modern dictionaries and encyclopedias do not provide such opportunities for many key terms, concepts and definitions in the humanitarian sphere, including medicine. The semantic representations that dominate in them are, by definition, unable to convey their content
Inforatio technique for treatment of patients with diabetic foot ulcers: a randomized clinical trial.
No full textRandomized clinical trial assessing a novel method for diabetic foot ulcer treatment.
Here in OSF the following are stored:
- the R scripts for the predefined analysis of trial results, uploaded before data are exported from RedCap and thereby before the R script analyses are executed.
- the blinded abstract, which is uploaded before unblinding of the dataset and analysis results.
Protocol published in BMJ Open: https://bmjopen.bmj.com/content/12/9/e062344.
Trial registered on ClinicalTrials.gov with ID: NCT05189470.
Statistical analysis codes made public on GitHub before data were exported from RedCap and analyses were conducted - link to GitHub: https://github.com/drsamoe/rct-inforatio-analysis
Elaboration about the R scripts:
The R scripts are listed by numbers in the order that they are supposed to be run. It is especially important to run the to first scripts (1_ and 2_) before the rest of the scripts are run.
Anywhere in the scripts were 'Path_to_the_folder_in_the_working_directory' is written must be replaced with the path to the folder used within the working directory. The working directory has to be defined in script 2_ before the rest of the scripts are run
Effective Primary Health Care (PHC) Strategies Aimed at Vulnerable Indigenous, Migrant, and Rural Populations in Colombia: A Scoping Review.
No full textBackground: Primary Health Care (PHC) has established itself as a cornerstone for strengthening health systems and mitigating inequalities, particularly among populations that have historically faced barriers to access. In Colombia, despite regulatory advancements and the adoption of territorially focused models, significant gaps persist, affecting indigenous communities, migrant populations, and inhabitants of rural areas. Although numerous initiatives have been implemented nationwide, evidence remains scattered across scientific literature, institutional reports, and technical documents. This fragmentation hinders a comprehensive understanding of which strategies have been developed, their specific characteristics, and the conditions under which they have proven effective.
Objective: To map, describe, and synthesize available evidence regarding PHC strategies, programs, interventions, or models implemented in Colombia targeting vulnerable indigenous, migrant, and rural populations, identifying their main characteristics, reported outcomes, barriers, and facilitators.
Methods: This scoping review protocol will be developed following the Joanna Briggs Institute (JBI) methodological guidance and reported in accordance with the PRISMA-ScR extension. The research question and eligibility criteria were structured using the PCC framework: Population (indigenous, migrant, and rural populations in Colombia), Concept (PHC strategies and interventions), and Context (services and institutions within the Colombian health system). A systematic search will be conducted across four databases (Scopus, PubMed, Web of Science, and LILACS), complemented by grey literature and institutional reports. Qualitative, quantitative, and mixed-methods studies, as well as descriptive analyses and technical documents published in Spanish or English since 2011, will be included. Two reviewers will select documents and extract data using a JBI-based matrix, and the synthesis will be presented narratively and categorized.
Expected Results: The review is expected to identify the array of PHC strategies implemented in indigenous and rural territories, as well as in areas with migrant populations, describing their scope, differential approaches, stakeholders involved, and outcomes regarding access, continuity, and quality of care. Furthermore, it anticipates recognizing recurrent barriers and facilitators that have influenced implementation, as well as knowledge gaps requiring further investigation.
Conclusions: This review will facilitate the integration and clarification of existing evidence on PHC strategies targeting vulnerable populations in Colombia. It will provide relevant insights for policy formulation, territorial planning, and the strengthening of culturally pertinent interventions aimed at reducing health inequities
Innovations in Practice: A Pilot Randomised Trial on Smartphone and Social Media Abstinence: Effects on Sleep Quality and Psychological Well-being in Adolescents
No full textThere is growing concern that smartphones and social media (S/SM) disrupt adolescent sleep, wellbeing and cognition, yet causal evidence from robust interventions is limited. To assess the acceptability of a total 21-day S/SM detox we conducted a preregistered (https://osf.io/79zd2) pilot randomised control trial with eighty-two adolescents aged 13-18 years from UK schools. Participants were randomly assigned to a total S/SM detox (N=26), total S/SM detox with access to a basic “brick” phone (N=26) or a business-as-usual control (N=30). Pre-and post-intervention measures of sleep, wellbeing, and cognition were collected using surveys, wearables, and cognitive tasks. Retention was high, with 13% attrition across groups. At 21-days, one or both detox groups showed tentative improvements in sleep duration, daytime sleepiness, depressive symptoms, perceived stress, and working memory relative to the controls, however these changes were not maintained at a two-month follow-up. Open-ended post-detox reflections reflected a range of both positive and negative experiences, with reported challenges including boredom, functional reliance on smartphones, and fear of missing out. Nevertheless, 83% endorsed the need for government action. Digital detoxes appear feasible for generating causal evidence; however, they can also pose functional challenges to young people. Fully powered trials should address these challenges, potentially via more targeted intervention approaches (e.g. switching off the internet on smartphones, particularly at bed-time)
Education Psychological Challenges and Research Gaps in GenAI-Integrated Creative Disciplines: A Scoping Review
No full textThis scoping review systematically synthesizes empirical studies on the application of Generative AI (GenAI) tools in creative education (e.g., for industrial design, architectural design, and visual communication design students), focusing on the negative psychological responses induced by GenAI—including career anxiety, creativity anxiety, professional identity threat, and concerns about self-efficacy—and integrating theoretical frameworks such as Self-Determination Theory (SDT) and Extended Technology Acceptance Model (ETAM) to clarify the current research status, core impact dimensions, and existing research gaps in this field
Still Images, Shifting Minds: Testing the Transformative Effects of Evocative Visuals
No full textThis dataset accompanies a study on aesthetic perception and encounter‑proneness. The project examined how individual differences in the tendency to perceive symbolic or numinous significance (“encounter‑proneness”) shape responses to curated visual stimuli. An online convenience sample of 167 adults rated 100 images (50 “enchanted,” 50 “disenchanted”) using brief measures of six environmental Gestalt variables and situational enchantment. Results showed that encounter‑prone participants consistently evaluated both image types as more immersive and meaningful than encounter‑resistant participants, and they sustained situational enchantment even with low‑valence stimuli. These findings support a co‑constructive model of aesthetic engagement, highlighting the dynamic interplay between external stimuli and internal dispositions. The raw dataset provided here includes all participant ratings and measures used in the analyses
Designing the built environment of outpatient mental healthcare facilities: A systematic scoping review
No full textThis systematic scoping review seeks to examine and synthesise current evidence and design principles in relation to the effects of the built environment of outpatient mental health facilities on user outcomes
A Rare Integrated Cognitive Architecture: Theoretical Model of a Human Exhibiting Advanced Cognition, Hyper-Motivation, and Enhanced Metacognitive Self-Analysis
No full textThis project presents a conceptual and phenomenological framework describing an integrated cognitive profile characterized by high levels of cognitive integration, metacognition, and sensitivity to internal processing load.
Across versions 1.0 to 4.0, the model evolves from conceptual exploration to theoretical refinement, functional stabilization, and finally conceptual closure. The most recent and complete version, HCIR v4.0, consolidates integrated self-regulation as the central functional axis of the model, explicitly distinguishing temporary access to states of cognitive hyperintegration from maladaptive persistence in such states, and incorporating biological and systemic limits as structural components of the framework.
Earlier versions are provided for reference to document the conceptual evolution of the model.
This work is intended as a non-diagnostic, non-hierarchical theoretical framework for exploration and research purposes, grounded in phenomenological observation and aligned with neuroscientific principles