1,721,527 research outputs found
Personalized Ubiquitous Health and Wellness Care: The KNOWLEDGE-CARE Vision
No full textThe KNOWLEDGE-CARE vision is to enable new e-health services that are personalized, preventive, predictive, pre-emptive, participatory, pervasive and precise. This vision aims to make a move from reactive medicine to predictive medicine, developing dynamic and responsive models through knowledge extraction and using such models for personalized clinical healthcare. The proposed healthcare ecosystem can learn over time and can adapt to the variation seen in the actual real-world population
An investigation about an automotive DI solenoid injector dynamic flow shift in durability
No full textA novel approach to minimizing gingival recession in the treatment of vertical bony defects.
No full textBackground: In ideal conditions, the gain in clinical attachment following regenerative therapy of infrabony defects should be equal to probing depth reduction; thus, gingival recession should not increase as a consequence of the treatment procedures. The goal of the study was to evaluate the effectiveness of a surgical technique for the treatment of intrabony defects aimed at minimizing gingival recession and increasing the potential for clinical periodontal regeneration. Methods: Fifteen deep intrabony defects were treated with cause-related therapy aimed at eliminating bleeding on probing in the surgical area with minimal mechanical trauma to the root and the soft tissues. Four weeks later, a surgical technique combining the simplified papilla preservation approach at the level of the defect and the coronally advanced buccal flap at the adjacent teeth was performed. Enamel matrix protein was used in the intrabony defect. Soft tissue measurements were made before cause-related therapy, before and after surgery, and at the 1-, 6-, and 12-month follow-up visits. The clinical reevaluation was made 1 year after the surgery. Results: No changes in the position of the buccal and interproximal soft tissues next to the defect area were observed before and after cause-related therapy or when comparing the baseline (before surgery) and 1-year follow-up visits. The clinical attachment gain (5.9 ± 1.4 mm), probing depth reduction (6.0 ± 0.8 mm), and radiographic bone level gain (5.0 ± 0.5 mm) were statistically and clinically significant, whereas no statistically significant increase in gingival recession (0.1 ± 1.0 mm) was noted during the observation period. Conclusions: It is possible to avoid statistically and clinically significant changes in the position of the soft tissues when treating vertical bony defects. This can be accomplished by minimizing soft tissue trauma durinq cause-related therapy and by advancing the buccal flap coronally during the surgery
The papilla amplification flap. A surgical approach to narrow interproximal spaces in regenerative procedures.
No full textA modified surgical approach to interproximal guided tissue regeneration procedures (GTR) was used when anatomic conditions at the defect-associated interdental area rendered papilla preservation techniques very difficult. The main goal of this study was to evaluate the effectiveness of the papilla amplification flap (PAF) in obtaining and maintaining primary soft tissue closure of the interdental space above nonresorbable, titanium-reinforced, expanded polytetrafluoroethylene (e-PTFE) membranes and to quantify the regenerative outcomes obtained using this procedure. Seventeen patients with one deep intrabony defect associated with a narrow interproximal space were selected for this case-series clinical study. The application of the PAF in combination with e-PTFE membranes resulted in clinically and statistically highly significant gains in clinical attachment levels (4.7 ± 1.4 mm) and reductions in probing pocket depth (6.3 ± 1.3 mm) after 1 year. Primary soft tissue closure of the interdental space was obtained in 100% of cases after completion of the surgery and maintained in 65% of cases during the initial healing period (6 weeks). Results from the present study indicate that the PAF can be considered a suitable soft tissue surgical approach for GTR treatment of intrabony defects when papilla preservation techniques are not recommended because of unfavorable local anatomic conditions interproximally
Long-term outcome following treatment of multiple Miller class I and II recession defects in esthetic areas of the mouth.
No full textBackground: Multiple recession defects can be successfully treated using envelope-type coronally advanced flaps. The aim of the present study was to evaluate the long-term (5 years) stability of clinical outcomes achieved with the surgery and the association between patient variables and long-term stability.
Methods: Seventy-three Miller Class I and H gingival recessions affecting 22 young, systemically healthy subjects were treated with coronally advanced flaps with no releasing incisions. All patients were instructed to perform a coronally directed roll technique to minimize the toothbrushing trauma to the gingival margin. The clinical reevaluation was made I year after the surgery. At this point, 13 patients took part in a supportive periodontal care program consisting of oral hygiene instructions, control of toothbrushing technique, and professional tooth cleaning every 4 months. The remaining nine patients did not participate and received only sporadic care by general dentists. At 5 years post-surgery, all patients were reexamined.
Results: At the 5-year examination, 94% of the root surfaces initially exposed due to gingival recession were still covered with soft tissue, and 85% of the treated recession defects showed complete coverage. Complete root coverage in all recessions was maintained in 15 out of 22 patients (68%). The long-term stability of the soft-tissue margin in the treated sites was significantly influenced by the patient's regular participation in the recall program and the susceptibility to gingival recession in other areas of the mouth. A statistically significant increase of keratinized tissue (0.80 +/- 0.64 mm) was observed between the 1- and 5-year observation visits, and the average increase of keratinized tissue between the baseline and the 5-year follow-up amounted to 1.38 +/- 0.90 mm. This increase was significantly affected by the baseline keratinized tissue (KT) and recession (REC) depth: in particular, the 5-year increase in the amount of keratinized tissue was greater in sites with a greater recession depth and lower amount of keratinized tissue at baseline.
Conclusions: 1) The successful root coverage results obtained with the coronally advanced flap for multiple recession defects were well maintained over the 4-year observation period. 2) Negative patient characteristics such as a lack of compliance with a supportive care program and individual susceptibility to gingival recession were significantly associated with the recurrence in gingival recession. 3) The increase in keratinized tissue height that followed the coronally advanced flap procedure may be attributed to the tendency of the mucogingival line to regain its genetically determined position
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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