1,720,975 research outputs found
Alterations in Cardiometabolic and Vascular Function Measures during the Menopause Transition
No full textBackground: The risk of cardiovascular disease (CVD) in women accelerates after midlife, suggesting a contribution of the menopause transition (MT). A piecewise-linear increase in a CVD predictor close to the final menstrual period (FMP) would be indicative of a menopause contribution.
Objectives: This dissertation included three papers with the following objectives: to determine whether arterial stiffness (paper 1) and abdominal visceral adipose tissue (VAT, paper 2) show piecewise-linear increases close to the FMP, and whether menopause-related VAT changes predict carotid artery intima-media thickness (cIMT, paper 2). In paper 3, we sought to determine whether distinct trajectories of systolic (SBP) and diastolic (DBP) blood pressure over the FMP can be identified, whether any SBP or DBP trajectory shows a piecewise-linear increase close to the FMP, and whether menopause-related factors (age at menopause, vasomotor symptoms, estradiol, and follicle-stimulating hormone [FSH]) predict blood pressure trajectories.
Methods: Participants from the Study of Women’s Health Across the Nation (SWAN; n=3,302, age: 46.3±2.7) and SWAN Heart Ancillary Study (n=362, age: 51.1±2.8 years) who had 2 measures of arterial stiffness and VAT and 17 measures of blood pressure over the MT were included. FMP-anchored piecewise-linear mixed effects models and group-based trajectory modeling were used for the analyses. Models were adjusted for age at the FMP, and demographic, lifestyle, and CVD risk factors.
Results: Over 2.3 years of follow-up, both arterial stiffness and VAT showed a piecewise-linear trajectory with significant accelerated increases close to the FMP. Menopause-related VAT increase predicted greater cIMT. Over 19.1 years of follow-up, women experienced three distinct SBP trajectories with 36% of the SWAN cohort experiencing a piecewise-linear increase trajectory with a significant accelerated increase close to the FMP. The other SBP trajectories and all DBP trajectories did not show menopause-related increases. An older age at menopause and vasomotor symptoms predicted a higher SBP trajectory and higher FSH levels predicted a lower SBP overtime.
Conclusions: The MT is associated with increases in cardiometabolic and vascular function measures beyond aging. It is prudent to timely detect increases in CVD risk factors during the MT and emphasize lifestyle changes with the aim of combating such increases
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Symptoms trends after hematopoietic stem cell transplantation
No full textObjective: To characterize patterns of symptom severity and determine interference of symptoms with daily activities after allogeneic and autologous hematopoietic stem cell transplantation (HSCT). Methods: A combined dataset of four different studies was used for the analysis with a total of 304 patients. MD Anderson Symptom Inventory – Bone Marrow Transplantation was the questionnaire used to evaluate symptoms severity and their interference with daily activities. These data were collected longitudinally. The analysis was based on each of the five worst symptoms and the mean of the worst five symptoms. The data were analyzed using linear mixed models, where time was the number of days from day of transplant. Results: The five worst symptoms based on the grand mean were fatigue, physical weakness, sleep disturbance, lack of appetite, and pain. Older patients reported more fatigue, physical weakness, and they had higher mean of the worst five symptoms. Male patients had significantly lower fatigue compared to female patients. Sleep disturbance was less in Hispanic compared to white non-Hispanic patients. The interaction between type of transplant and time was significant in the mean of the worst five symptoms, fatigue, physical weakness, and lack of appetite. However, time, without interaction with transplant type, was a significant predictor of sleep disturbance and pain. Symptom severity was significantly correlated with symptoms interference at all time points; strongest correlation was at day 30. Conclusion: Age and the interaction between types of transplant and time are the main factors that determine symptoms severity for the worst five symptoms. This information is valuable when managing patients’ symptoms after they had HSCT and to tailor interventions according to different patient’s characteristics
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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