74 research outputs found

    Impact of Spondyloarthritis on Pregnancy Outcome: A Descriptive Analysis from a Specialized Center in Qatar

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    Samar Al Emadi,1 Nawal Nouman Hadwan,1 Rawan Saleh,1 Eman Satti,1 Rajvir Singh2 1Department of Rheumatology, Hamad Medical Corporation, Doha, Qatar; 2Medical Research Center, Statistics, Hamad Medical Corporation, Doha, QatarCorrespondence: Samar Al Emadi, Department of Rheumatology, Hamad General Hospital, PO Box 3050, Doha, Qatar, Tel +974 55550087, Email [email protected]: Spondyloarthritis (SpA) most commonly presents at childbearing age; thus, pregnancy is of concern. However, data on pregnancy outcomes in these patients are limited.Purpose: This study aimed to retrospectively describe pregnancy outcomes in patients with SpA from the Middle East.Patients and Methods: We reviewed the electronic health records of all pregnant women attending a specialized pregnancy and rheumatic disease clinic between 2016 and 2022. All pregnant patients diagnosed with axial spondyloarthritis (axSpA) and peripheral SpA were included. Data on adverse maternal and fetal outcomes were collected.Results: Fifty-seven eligible pregnancies were identified from hospital records: 10 pregnancies ended in early miscarriage. Forty-seven pregnancies resulted in live singleton births, 25 in patients with peripheral SpA and 22 with axSpA. Human leukocyte antigen B27 was positive in 7 (15%) patients and only in women with axSpA. Twenty-nine (64%) patients received treatment throughout pregnancy. Consistent biologic disease-modifying antirheumatic drug (bDMARD) use was high, in eight (32%) patients with peripheral SpA and in nine (41%) with axSpA. A conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) was used as treatment in 11 (50%) patients with peripheral SpA and two (8%) with axSpA. Twenty-two (53%) neonates were delivered by cesarean section, 19 (40%) by normal vaginal delivery and three (6%) by assisted delivery. Additionally, 44 (94%) deliveries were at term, and 42 (91%) neonates had a normal birth weight. Exploration of a subgroup showed no difference in reported outcomes between patients treated with bDMARD and those treated with csDMARD.Conclusion: This descriptive study reports a high rate of favorable pregnancy outcomes in patients with SpA. There was no evidence to suggest a difference in pregnancy outcomes between women with axSpA and those with peripheral SpA. This study was one of the first reports from the Middle East. Further studies with larger sample size are warranted.Keywords: axial spondyloarthritis, pregnancy, pregnancy outcomes, neonatal health, maternal healt

    Vitamin D Status in Pregnant Women and their Babies in Qatar

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    Hafidh Muhammed b. Omar ai-Imadi and edition critique of his book "Mufradat al-Qurra al-Sab"

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    Bu araştırma, Hafız İmadi'nin (ö. h.783) Mufredatu'l-Kurrai's-Seb'a adlı eserinin tahkikidir. Kitabın başlangıcından İbn Amir eş-Şami müfredesine kadar tahkik edilmiştir. Müellifinin VII. asrın alimlerinden ve disiplininde gözde bir isim olmasından dolayı bu eser, kıraat ilmi hususunda önemli bir eser sayılmaktadır. Çalışmada kariler ayrı bir şekilde incelenmektedir, ihtilaf ve ittifak yönleri ortaya koyulmaktadır. Yapıtta özellikle usulde ilkeleri ihlal etmeyen bir özetleme/ihtisar, ferşte gerekli olan şekilde detaylara girilme metodu benimsenmiştir. Bu tez giriş, dört bölüm, Sonuç ve ön sözden oluşmaktadır. Girişte eserin öneminden, seçilme nedeninden ve çalışma planından bahsedilmektedir. ve kıraat ilmi tanımlanmış, yedi harf ile kıraat ilmi arasındaki farklar açıklanmış, sahih kıraatin esasları vurgulanmıştır. Müfredeler tarif edilmiş, yedi mütevatir kıraatin imamları ve ravileri, Şatıbiyye tarikine göre anlatılmıştır. Birinci Bölüm: Müellifin hayatına dair kısa bir çalışma içermektedir. İkinci Bölüm: Kitaba ilişkin muhtasar bir araştırma barındırmaktadır. Üçüncü Bölüm: İmadi'nin Mufredatu'l-Kurrai's-Seb'a genel bilgiler. Sonuç bölümünde araştırmada ulaşılan en önemli sonuçlar ortaya konmuştur: - Kitabın İmam İmadi'ye nisbetinin doğruluğu ve başkalarına yapılan atıfların yanlışlığını ispatlanmıştır. - İmadi'nin biyografisi mevcut imkanlar çerçevesinde sunulmuş, kendisinin kıraat alanında mühim bir yeri olduğu vurgulanmıştır. - İmam Ahmed b. Halil el-Ferahidi'den nakledilen yedi harfin yedi kıraat olduğunu söyleyen görüşün doğru olmadığı, yedi kıraati toplayan alim Mücahit onun vefatından 75 sene doğduğu saptanmıştır. Dördüncü Bölüm: Tahkik hususunda üç nüshanın karşılaştırılması yapılmış, dipnotta nüsha farkları belirtilmiş, gerekli açıklama ve yorumlarla birlikte sunulmuştur. This thesis is the investigation and study of the (Mufradat Alq-urrat AlSabea) book by Al-Emadi (T 783) from the beginning of the book to the Imam Ibn Amer Al-Shami. This book presented as one of the most important books in the science of the "Al-Qurra'" with mentioning the agreement and the difference between the narrators in a manner that combines the unkind abbreviation especially in the fundamentals and the verbiage which are not boring especially in the science of "Al-Farsh". Where it has been worked on according to the method of achieving scientific research, it consists of an introduction and two sections; The introduction: contains the importance of the topic, the reason for its selection and the research plan. And the first section is The study: It contains a preamble, and three chapters, and its conclusion. While the preamble contains: Introducing the science of readings, and explaining the difference between the seven letters and the seven readings, as well as the conditions for accepting readings, and then introducing vocabulary and the most important literature in it and then the definition of the seven readers and their narrators and their methods of "AlShatbyah". As for the first chapter: it contains a brief study about the author. The second chapter contains a study about the book. The third chapter contains General information about the "Al-Mofrdat". The last part is the conclusion: I mentioned the most important findings of the study, including (Determining the author of the (Mufradat Alq-urrat Al-Sabea) book and its attribution to Imam Muhammad bin Amr Al-Emadi (T. After 783) and proof of his fault attributed to others, detection of a translation; And if it was not sufficient for al-Emadi, may God have mercy on him, and to prove the year of his death, while emphasizing that al-Emadi, may God have mercy on him, is a distinguished scholar who is proficient in the sciences of readings and the Arabic language and clarification and statement of the prevailing error that Imam Ahmed bin Khalil Al-Farahidi had interpreted the seven letters with the seven famous readings Especially if we know that Ibn Mujahid who collected the seven recitations was born after the death of Al-Farahidi by (seventy-five years).). The second section: The investigation: The complete investigative text was mentioned in it after his interview in three written copies, and the difference between them was fixed in the margin with comment and clarification on what needs to be clarified

    Interleaved Multilevel Boost Converter With Minimal Voltage Multiplier Components for High-Voltage Step-Up Applications

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    In this article, a new interleaved multilevel boost converter (interleaved-MBC) is suggested with minimal voltage multiplier (VM) cells for high-voltage step-up applications. The interleaved-MBC is derived in such a way that the maximum utilization of the VM circuit operation can be achieved by the interleaved structure. Furthermore, compared to existing multilevel interleaved converters, the reduced number of capacitors and diode with equal voltage rating makes it more attractive. Similar to the existing multilevel converter, the feature of the interleaved-MBC provides the extension of the number of levels to achieve the necessary voltages just by adding similar capacitor-diode stages (single capacitor and single diode are required to increase the stage by one). The features like continuous input current, low-input ripples, high voltage conversion ratio, and reduced stress on devices make the proposed converter more suitable for the voltage step-up applications, such as dc link, hybrid distribution systems, hybrid photovoltaic systems, etc. The detailed analysis of the converter is carried out by considering the nonidealities in the power circuit. The operation of the interleaved-MBC is presented for continuous and discontinuous conduction modes with boundary conditions. The components selection criterion and the comparison of converters are presented with suitable discussions. The converter is experimentally tested, and the obtained results validate its performance and functionality.Manuscript received October 5, 2019; revised January 11, 2020 and March 20, 2020; accepted April 20, 2020. Date of publication May 5, 2020; date of current version July 31, 2020. This work was supported in part by the Qatar National Library, Doha, Qatar, and in part by the Qatar National Research Fund, Qatar Foundation, under NPRP Grant X-033-2-007. Recommended for publication by Associate Editor Y. Siwakoti. (Corresponding author: Atif Iqbal.) Mohammad Meraj, Atif Iqbal, and Nasser Al-Emadi are with the Department of Electrical Engineering Qatar University, Doha, Qatar (e-mail: Meraj@ qu.edu.qa; [email protected]; [email protected]).Scopu

    Real-Time Fault Detection and Identification for MMC Using 1-D Convolutional Neural Networks

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    Automated early detection and identification of switch faults are essential in high-voltage applications. Modular multilevel converter (MMC) is a new and promising topology for such applications. MMC is composed of many identical controlled voltage sources called modules or cells. Each cell may have one or more switches and a switch failure may occur in anyone of these cells. The steady-state normal and fault behavior of a cell voltage will also significantly vary according to the changes in the load current and the fault timing. This makes it a challenging problem to detect and identify such faults as soon as they occur. In this paper, we propose a real-time and highly accurate MMC circuit monitoring system for early fault detection and identification using adaptive one-dimensional convolutional neural networks. The proposed approach is directly applicable to the raw voltage and current data and thus eliminates the need for any feature extraction algorithm, resulting in a highly efficient and reliable system. Simulation results obtained using a four-cell, eight-switch MMC topology demonstrate that the proposed system has a high reliability to avoid any false alarm and achieves a detection probability of 0.989, and average identification probability of 0.997 in less than 100 ms. - 2018 IEEE.Manuscript received October 23, 2017; revised February 11, 2018 and March 27, 2018; accepted April 16, 2018. Date of publication May 3, 2018; date of current version June 28, 2019. This work was supported by the National Priorities Research Program award (NPRP10-1203-160008) from the Qatar National Research Fund, a member of the Qatar Foundation. (Corresponding author: Serkan Kiranyaz.) S. Kiranyaz, A. Gastli, L. Ben-Brahim, and N. Al-Emadi are with the Department of Electrical Engineering, Qatar University, Doha 2713, Qatar (e-mail: [email protected]; [email protected]; [email protected]; [email protected]).Scopu

    A Novel Modified Switched Inductor Boost Converter with Reduced Switch Voltage Stress

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    Recently, switched inductor (SI) and switched capacitor techniques in dc-dc converter are recommended to achieve high voltage by using the principle of parallel charging and series discharging of reactive elements. It is noteworthy that four diodes, one high-voltage rating switch, and two inductors are required to design classical SI boost converter (SIBC). Moreover, in classical SIBC, the switch voltage stress is equal to the output voltage. In this article, modified SIBC (mSIBC) is proposed with reduced voltage stress across active switches. The proposed mSIBC configuration in this article is transformerless and simply derived by replacing the one diode of the classical SI structure with an active switch. As a result, mSIBC required low-voltage rating active switches, since the total output voltage is shared into two active switches. Moreover, the proposed mSIBC is low in cost, provides higher efficiency, and requires the same number of components compared with the classical SIBC. The continuous conduction mode and discontinuous conduction mode analysis, the effect of nonidealities on voltage gain, design methodology, and comparison are presented in detail. The operation and performance of the designed 500-W mSIBC are experimentally validated under different perturbations.Manuscript received July 14, 2019; revised October 15, 2019 and December 13, 2019; accepted January 3, 2020. Date of publication February 5, 2020; date of current version October 30, 2020. This work was supported by Qatar University High Impact under Grant QUHI-CENG-19/20-2, from the Qatar University. The publication charges are funded by the Qatar National Library. The statements made herein are solely the responsibility of the authors. (Corresponding author: Atif Iqbal.) S. Sadaf, M. Meraj, A. Iqbal, and N. Al-Emadi are with the Department of Electrical Engineering, Qatar University, Doha 2713, Qatar (e-mail: [email protected]; [email protected]; [email protected]; [email protected]).Scopu

    A comparison of microleakage of fissure sealants following three different application techniques :

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    PLEASE NOTE: This work is protected by copyright. Downloading is restricted to the BU community: please log in with a valid BU account to access and click Download. If you are the author of this work and would like to make it publicly available, please contact [email protected] (MSD) --Boston University Institute for Dental Research and Education, Dubai, 2011 (Pediatric Dentistry).Includes bibliographic references: leaves 86-95.Purpose: The purpose of this in vitro study was to compare the microleakage of fissure sealant placed on the occlusal surface of premolars using three different application techniques. Methods: A total of ninety four extracted sound human premolar teeth were assigned in this in vitro study. The samples were kept in distilled water for not more than a week and then randomly were distributed into three different test groups with 30 teeth in each; (A) teeth in the first group were treated with 37% phosphoric acid etching and Clinpro fissure sealant; (B) teeth in the second group were treated with 37% phosphoric acid, single bottle dentin bonding agent and fissure sealant; (C) teeth in the third group were treated with self etch adhesive and fissure sealant. Groups B and C were further divided equally into two subgroups based on light curing of dentin bonding agent and self etch adhesive prior to the application of sealant. A negative control of 2 teeth and a positive control group of 2 teeth were included to confirm that the basic conditions of the experiment are able to produce negative and positive results. Samples were thermocycled, stained with 5% methylene blue, sectioned and examined for microleakage under the stereomicroscope with a magnification range of X30 to X40. To determine the most appropriate time for maximum dye penetration, a pilot study of 12 teeth was conducted. Groups were compared using Pearson Chi square analysis. Results: No dye penetration was observed in 16, 7, and 11 teeth for groups A, B, and C respectively. Statistically significant difference was found in microleakage between the use of different application techniques (P[less than] 0.01). Etch and sealant group exhibited significantly higher microleakage compared to the other groups. Conclusion: The application of a bonding agent layer prior to a sealant afforded less microleakage than when no bonding agent was used. Furthemore, the separate curing of the bonding agent resulted in significantly less microleakage (P[less than] 0.01). Clinical trials should be performed to evaluate the performance of these techniques before definitive conclusions can be drawn

    Trends in Student Radicalization across University Campuses in Afghanistan

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    This study aims to examine the trends in student radicalization across eight university campuses in Afghanistan. We conclude from our survey of student and staff views and an analysis of the character of protests across campuses that the extent of student radicalization varies. In particular, we come to three noteworthy findings. First, most university students are more concerned over prospects of post-graduation follow-on careers than ideological ambition. Second, while we find that most students and lecturers denounce radical views and violence, a relatively more aggressive response to both the policies of the Afghan government and the armed international intervention exhibited by students from universities in Kabul, Qandahar and Nangarhar suggests differentiated patterns across university campuses, with these campuses suggestive of a stronger tendency toward radicalized views. Finally, as an institution, the university does not play a strong role in the radicalization of its students. Rather, a charged political climate and the readily available opportunity to mobilize quickly enable students to stand in protest rather easily. However, findings also suggest that it is this same easy access to mobilize in protest that seems to attract a number of external groups as evident by the black, white and green flags representative of al-Qaeda, the Taliban, and the militant wing of Hezb-e- Islami Hekmatyar. Moreover, it is these protests that seem to encourage polarization and consequential division on campus which increasingly resemble the practice of takfir. Referring to the practice of excommunication wherein one Muslim declares that another Muslim has abandoned Islam, takfir is in direct competition with the more tolerant teachings common to the characteristically liberal curriculum of public universities. While protest in and of itself is a characteristic common to progressive democracies, evidence suggests that some student protests do call for division along sectarian lines or the suppression of women’s rights, both of which stand in contradiction to democratic principles and pose a threat to stability. With more than sixty-three percent of the Afghan population under the age of twenty-four, left unchecked such influence has the likelihood and potential to expand with substantial consequences for development and security in Afghanistan. As Afghanistan moves into a new phase of its era of state-building, a special focus on meeting the needs of its youth and in particular of Afghan university students is indispensable in meeting and maintaining lasting stability and prosperity. This study is the first part of an ongoing series of papers dedicated to examining the trends in radicalization across the various sectors throughout Afghanistan. Launched in late 2013, we plan follow-on studies to complement the series, including examinations of the trends in radicalization in madrassas across Afghanistan and within the Afghan security forces
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