28 research outputs found
Porous organic crystals crosslinked by free-radical reactions
No full textTwo hydrogen-bonded crosslinked organic frameworks (HCOFs) were synthesized via free radical reactions utilizing butadiene and isoprene as crosslinkers. These HCOFs exhibit high crystallinity, enabling detailed structural characterization via single-crystal X-ray diffraction analysis. Subsequently, one of the olefin-rich HCOFs was converted to a hydroxylated framework through hydroboration–oxidation while maintaining the high crystallinity.This article is published as Samanta, Krishanu, Jiashan Mi, Albert D. Chen, Fangzhou Li, Richard J. Staples, Aaron J. Rossini, and Chenfeng Ke. "Porous organic crystals crosslinked by free-radical reactions." Chemical Communications 60, no. 57 (2024): 7311-7314. doi: https://doi.org/10.1039/D4CC02454K
Preliminary physico-phytochemical study of the leaves parts of Hygrophila difformis Blume
No full textABSTRACT Hygrophila difformis Blume (Family-Acanthaceae) and has great medicinal importance like An antibacterial activity, high insecticide activity and Tribal's are also used as anticoagulants. It is very useful in tropical fresh water aquarium plant and Environmental importance Ornamentals plants. In present study deals with the characterization of morphological features, determination of physical constant such as the total ash value, acid insoluble ash value and water soluble ash value were 1.97%, 0.59%, 1.37% respectively. Loss of weight drying was 4.5%, the percent yield for ethanol 9.12% and aqueous 5.45%
Emphysematous pancreatitis predisposed by Olanzapine
No full textA 32-year-old male presented to our intensive care unit with severe abdominal pain and was diagnosed as acute pancreatitis after 2 months of olanzapine therapy for bipolar disorder. His serum lipase was 900 u/L, serum triglyceride 560 mg/dL, and blood sugar, fasting and postprandial were 230 and 478 mg/dL, respectively on admission. Contrast enhanced computed tomography (CECT) of abdomen was suggestive of acute pancreatitis. Repeat CECT showed gas inside pancreas and collection in peripancreatic area and patient underwent percutaneous drainage and antibiotics irrigation through the drain into pancreas. We describe the rare case of emphysematous pancreatitis due to development of diabetes, hypertriglyceridemia and immunosuppression predisposed by short duration olanzapine therapy
Preliminary physico – phytochemical and phytocognostical evaluation of the leaves parts and evaluation of herbal ointment using leaves of Achyranthes aspera L. Leaf extract
No full textHerbal plants are huge sources of neutraceuticals, prevent the different disease or maintain healthy life. Plant produces primary metabolites for their basic survival and secondary metabolites for their ecological, taxonomical and biochemical differentiation and diversity. Achyranthes aspera L. (Family Amaranthaceae) are broadly used in traditional system of medicine throughout different part of India, South Andaman Island, Pacific Island, Baluchistan, Tropical Asia, America, and Australia. It has great medicinal importance like to stomach tonic, diuretic, laxative, anthelmintic, anti hyperlipidemic, expectorant, anti-inflammatory, anti-bacterial, anti-fungal, hypoglycemic, anti-asthmatic and anti-allergic etc. The study of diseases and their treatment are important part of our ancient time worldwide. The knowledge of medicinal plants must have been accumulated in the course of many centuries. Herbal medicine prepare different part of plant are used. Herbal drug is design as the alternative formulation for the external use in the form of ointment. For the clinical use the herbal ointment apply externally on human body. The main aims of this research are Preliminary physico–phytochemical & phytocognostical evaluation of the leaves parts and preparation of herbal ointment from the Achyranthes aspera. Achyranthes aspera L. plants used as antibacterial activity. Under this research work, it is design as herbal ointment with the help of Ethanolic extract of Achyranthes aspera and determines the anti-bacterial capacity on it. In vitro study the antibacterial activity of the Ethanolic extracts of dried leaves of Achyranthes aspera L. are determine by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the Ethanolic extract of Achyranthes aspera L. (10 % w/w) into aqueous cream we formulated herbal ointment. The emulsifying agent and simple ointment bases are added in above herbal ointment for increase the antibacterial effectiveness during in vitro evaluation. The current study deals with the characterization of morphological features, determination of physical constant such as the total cash value, water soluble ash value were 11.25%, 5.25% respectively. Loss of weight drying was 12.9%, foaming index>100, swelling index were1.5cm, the percent yield for petroleum ether 5.25%, chloroform 6.34%, ethanol 7.65%, and aqueous 8.35%, and determination of formulation and evaluation of herbal ointment using Achyranthes aspera L. leave extract
Formulation and evaluation of herbal ointment using Emblica officinalis extract
No full textHerbal medicine prepare various part of plant are used like flower, leaves, seeds, root etc. Instead off an herbal drug is design as the alternative formulation for the external use in the form of ointment. For the medicinal use the herbal ointment apply externally on human body. The main aims of this research are preparation of herbal ointment from the Emblica officinalis plants the antibacterial activity. Under this research work, it is design as herbal ointment with the help of methanolic extract of Emblica officinalis and determines the anti-bacterial capacity on it. In vitro study the antibacterial activity of the methanolic extracts of dried leaves of Emblica officinalis are determine by using the Agar cup plate method versus different bacteria such as Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa etc. By blending the methanolic extract of Emblica officinalis (10 % w/w) into aqueous cream we formulated herbal ointment. The emulsifying agent and simple ointment bases are added in above herbal ointment for increase the antibacterial effectiveness during in vitro evaluation. The herbal ointment is also better in comparison to a commercial brand of Gentamicin ointment. Emblica officinalis (Family Euphorbiaceae) are broadly used in traditional system of medicine throughout different part of India. It is used in the treatment of cold, anemia, dysentery, fever, gravel, sores. It is very important to standardize the plant part pharmacognostically for its utilization in different formulation. The current study deals with the determination of formulation and evaluation of herbal ointment using Emblica officinalis extract
Crystal Structure Landscape of a Triphenol: Polymorphism and Isostructurality in Solvates and Cocrystals, and Pentameric and Hexameric Aromatic Stacks
No full textCrystal Engineering of a Tetraphenol with Bispyridines toward Hydrogen-Bonded Emissive Cocrystals
No full textHerein, we report the cocrystals
of an AIEgenic tetraphenol, namely
tetrakis(4-hydroxybiphenyl)ethylene (THBPE), with a few bispyridyl
aza donors, built with phenol···pyridine hydrogen bonding.
We employed two different crystallization conditions: diffusion of
hexane into THF and slow evaporation from ethyl acetate. The former
condition readily afforded cocrystals in all instances except one,
whereas the latter afforded only one. Attempted cocrystallization
with 4,4′-bipyridine (BP) did not result in any cocrystals
but instead afforded THF solvates of the tetraphenol. The rigid coformers
4,4′-azopyridine (AP) and 1,2-bis(4-pyridyl)ethylene (BPE)
resulted in nonemissive close-packed cocrystal solvates. In both cases,
the THF solvent competes with the pyridyl moiety for hydrogen bonding
at two of the four possible sites in the tetraphenol, which is uncommon
for a phenol···pyridine supramolecular synthon. However,
the synthon wins out in the crystals from ethyl acetate solution with
one coformer (AP) to form a fully hydrogen bonded square lattice (sql) network. The moderately flexible 1,2-bis(4-pyridyl)ethane
(BPA) led to a close-packed hydrated cocrystal solvate. The highly
flexible 1,2-bis(4-pyridyl)propane (BPP) afforded emissive cocrystals,
with nanotubular pores of 10 Å diameter. The latter cocrystal
adopts aqtz topology with 8-fold interpenetration.
The last two cocrystals are emissive in the solid state, which is
unusual for phenol···pyridine hydrogen-bonded complexes.
The quantum yields of the solid-state emission exhibited by the lastlatter
two cocrystals are 16% and 25%, which are higher than that of the
tetraphenol at 9%. The observed emission property can be correlated
with how uniquely and efficiently the AIEgens are packed in the solid
with the assistance of coformers. The cocrystallization experiments
with rigid tetraphenol and diverse bispyridyl coformers also provide
insight into the formation of cocrystals along with solvates and hydrated
solvates. Notably, four among the five cocrystals reported herein
have Z′ = 2
Anthelmintic Activity of Hygrophila difformis Blume
No full textThis study evaluated the anthelmintic activity of the petroleum ether, benzene, chloroform, ethanol extracts of aerial parts of Hygrophila difformis (Family: Acanthaceae). The Pheretima posthuma were used for all the experimental protocol due to their anatomical and physiological resemblance with the intestinal roundworms of ruminants and human beings. The worms were treated with the extract solutions containing three different concentrations (10, 25 and 30 mg/ml), for each extracts supplemented with 1% gum acacia in normal saline at 37 ± 1°C. Albendazole at a dose of 10 mg/ml was used as reference. The effectiveness of the extracts was judged on the basis of the loss of spontaneous movement and/or death of the worms. Qualitative phytochemical analysis of different extracts of the plant was carried out following the standard procedure. All extracts at different dose levels effectively paralyzed and killed the worm in dose-dependent fashion (p < 0.001). Maximum anthelmintic activity was found with benzene extract. Cardiac glycosides, tannins, steroids, flavonoids and saponins were found positive in phytochemical analysis. The present study established the anthelmintic activity of H. difformis and can be utilized for the ruminants
Phytochemical screening, physochemical and microscopical evaluation of Hygrophila difformis aerial parts
No full textHerbal plants are marvelous source of traditional & modern medicine, useful for primary health care system globally. Herbal plants are also massive sources of neutraceuticals prevent the different disease and maintain healthy life style. The study of diseases and their treatment are important part of our ancient time worldwide. The awareness of medicinal plants must have been accumulated in the course of many centuries. Herbal medicine prepare different part of plant are used. Hygrophila difformis Blume is well known as water wisteria. It is tropical aquarium plant used as environmental ornaments. It is found in different part of India and Indian subcontinent including Bangladesh, Bhutan and Nepal. The plant is used as coagulant by tribal people of East Medinipur, dist West Bengal, India. The aerial part of the plant showed good anti-oxidant property, anthelmintic activity. Also ethanolic extract of aerial parts of the plant also showed CNS depressant activity. The main aims of this research are Preliminary physico– phytochemical & phytocognostical evaluation of the aerial parts of Hygrophila difformis Blume. The current study deals with the characterization of morphological features, determination of physical parameter such as the total ash value, water soluble ash, acid insoluble ash value were 14%, 5.25%, 6.81% respectively. Loss of drying was 13%, foaming index < 100, swelling index were 0.3cm, the percent yield for petroleum ether 3.29%, cyclo hexane 2.57% chloroform 1.99%, ethanol 9.15%, and aqueous 5.46%. Also determine the presence or absence of phytochemicals such as glycosides, tannins, steroids, flavonoids and saponins
The role of carbon dioxide insufflation of the pericardial field in open chamber cardiac surgery to prevent neurocognitive decline
No full textThis thesis was scanned from the print manuscript for digital preservation and is copyright the author.
Researchers can access this thesis by asking their local university, institution or public library to
make a request on their behalf. Monash staff and postgraduate students can use the link in the References field
