1,721,012 research outputs found
Hemostatic powders and gels in gastrointestinal endoscopy: current perspective and future recommendations
No full textRecurrent obstruction after surgical gastrojejunostomy in a rare case of gastric outlet obstruction: endoscopic ultrasound-guided gastrojejunostomy to the rescue
No full textAn unusual complication of a ventriculoperitoneal shunt: Endoscopic ultrasound-guided drainage of a giant cerebrospinal fluid pseudocyst
No full textBleeding parastomal varices in a case of decompensated cirrhosis with tubercular abdominal cocoon: endoscopic ultrasound-guided angioembolization with coil and glue to the rescue
No full textDevice assisted endoscopic full thickness resection in colorectum: A systematic review and meta-analysis
No full textBackground and aim: Endoscopic full thickness resection (EFTR) is emerging as an effective modality for mucosal and submucosal lesions in colorectum. In this systematic review and meta-analysis, we aimed to analyze the success and safety of device assisted EFTR in colon and rectum. Methods: A literature search was performed in Embase, PubMed, Medline databases for studies evaluating device assisted EFTR between inception to October-2022. The primary outcome of the study was clinical success (R0 resection) with EFTR. Secondary outcomes included technical success, procedure duration and adverse events. Results: 29 studies with 3467 patients [59% males, 3492 lesions] were included in the analysis. The lesions were located in right colon (47.5%), left colon (28.6%) and rectum (24.3%). EFTR was performed for sub-epithelial lesions in 7.2% patients. Pooled mean size of the lesions was 16.6 mm (95% CI 14.9 - 18.2, I 2 98%). Technical success was achieved in 87.1% (95% CI 85.1%-88.9%, I2 39%) procedures. The pooled rate of en bloc resection was 87.9% (95% CI 85.1%-88.9%, I2 50%) and R0 resection was 81.6% (95% CI 78.8% to 84.2%, I2 57%). In sub-epithelial lesions, pooled rate of R0 resection was 94.3% (95% CI 89.7% to 96.9%, I2 0%). Pooled rate of adverse events was 12.1%(95% CI 10.3%-14.1%, I2 44%) and major adverse events requiring surgery was 2.5% (95% CI 2.0%-3.1%, I2 0%). Conclusion: Device assisted EFTR is a safe and effective treatment modality in cases with adenomatous and sub-epithelial colorectal lesions. Comparative studies are required with conventional resection techniques including endoscopic mucosal resection and submucosal dissection
Endoscopic ultrasound-guided radiofrequency ablation of pancreatic insulinoma: a state of the art review
No full textIntroduction: Insulinomas are the most common functional pancreatic neuroendocrine tumors (PNETs) that lead to incapacitating hypoglycemia. Guidelines recommend surgical resection as the mainstay of management. However, surgery is fraught with complications, causing significant peri/post-operative morbidity. Since insulinomas are usually benign, solitary, small (<2 cm), and do not need lymphadenectomy, hence, in this regard, endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) is now being increasingly performed, to circumvent these adverse events and impairment of pancreatic function. Areas covered: A comprehensive literature search was undertaken across various databases (PubMed/Medline, Embase, Scopus), with no language restriction, for relevant articles (case series, reviews, case reports) pertaining to EUS-RFA for insulinoma and PNETs, till October 2023. In this review, we have explicated the role of EUS-RFA for insulinoma management, detailing thoroughly its mechanism of action, EUS-RFA devices with data on its safety and efficacy, and an algorithmic approach for its management. Expert opinion: EUS-RFA is being advocated as a 'mini-invasive' option with the potential to replace surgery as a first-line approach for benign, sporadic, solitary, and small (<2 cm) insulinomas. Under real-time guidance, EUS-RFA has immense precision, is safe, predictable, with acceptable safety profile. Presently, it is being frequently performed for high-risk or inoperable candidates. Current need-of-the-hour is a randomized controlled trial to substantiate its role in the therapeutic algorithm for insulinoma management
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
An ultra-dynamic anion-cluster-based organic framework
No full textPorous organic frameworks that can dynamically expand their voids to guest uptake remain formidable to design. The challenge comes from finding the balance between rigidity and flexibility. Rigidity is required to retain the framework, and the flexibility is needed for reversible expansion/contraction. Herein, we introduced bisulfate anion clusters as soft joints to construct a single-crystalline hydrogen-bonded cross-linked organic framework HCOF-6. Upon the uptake of guest molecules, the anion clusters of HCOF-6 were disrupted, allowing the crystal to expand rapidly (<40 min) to more than twice its original length. Removing these guests restored the anion clusters and the crystallinity of HCOF-6 quickly (<10 min). These guest-induced material size expansions and contractions are highly reversible, and the dynamic anion cluster dissociation-reassociation is confirmed by molecular dynamics simulations and solid-state NMR experiments. The guest-induced size change of HCOF-6 highlights a new approach to synthesize dynamic framework materials by introducing anion clusters.This is a manuscript of an article published as Samanta, Jayanta, Rick W. Dorn, Wenlin Zhang, Xuanfeng Jiang, Mingshi Zhang, Richard J. Staples, Aaron J. Rossini, and Chenfeng Ke. "An ultra-dynamic anion-cluster-based organic framework." Chem 8, no. 1 (2022): 253-267. DOI: 10.1016/j.chempr.2021.11.014. Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Copyright 2021 Elsevier Inc. DOE Contract Number(s): AC02-07CH11358; DMR‐1844920; 1919565.
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Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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