224 research outputs found
Influence of para substituents in controlling photophysical behavior and different non-covalent weak interactions in zinc complexes of a phenol based "end-off" compartmental ligand
No full textThree dinuclear zinc(II) complexes with "end-off" compartmental ligands, namely 2,6-bis(N-ethylmorpholine-iminomethyl)-4-R-phenol (I: R = -CH3, Cl, tBu) were synthesized with the aim of exploring the role of the para substituent present in the ligand backbone in controlling the structural diversity, photophys. properties and different weak interactions of the complexes. The complexes are [Zn2L1(CH3CO2)2]1/2[Zn(NCS)4].3/2H2O (1), [Zn2L2(CH3CO2)2]1/2[Zn(NCS)4] (2), and [Zn2L3(CH3CO2)2]1/2[Zn(NCS)4] (3),. All three species, with the general formula 2[Zn2L(CH3COO)2][Zn(NCS)4], show the complex anion Zn(NCS)42- as a common structural feature decisive for crystn. All of them possess several noncovalent weak interactions where the nature of the "R'' group plays an essential role as exposed by DFT study. Besides exhibiting fluorescence behavior, the complexes also show para substitution controlled phosphorescence both at room and low temp. Anisotropy studies suggest the existence of complexes 2 and 3 as dimers in soln. The origins of the unusual room temp. phosphorescence and fluorescence behavior of the complexes were rationalized in the light of theor. calcns. [on SciFinder(R)
A Complex Relationship Among the Circadian Rhythm, Reward Circuit and Substance Use Disorder (SUD)
No full textSaptadip Samanta,1 Debasis Bagchi,2,3 Mark S Gold,4 Rajendra D Badgaiyan,5 Debmalya Barh,6 Kenneth Blum7– 12 1Department of Physiology, Midnapore College, Midnapore, West Bengal, 721101, India; 2Department of Biology, College of Arts and Sciences, Adelphi University, Garden City, NY, USA and Department of Psychology, Gordon F. Derner School of Psychology, Adelphi University, Garden City, NY, USA; 3Department of Pharmaceutical Sciences, College of Pharmacy, Southern University, Houston, TX, 77004, USA; 4Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA; 5Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, OH, USA; 6Centre for Genomics and Applied Gene Technology, Institute of Integrative Omics and Applied Biotechnology, Nonakuri, Purba Medinipur 721172, West Bengal, India; 7Division of Addiction Research & Education, Center for Sports, Exercise, and Mental Health, Western University Health Sciences, Pomona, CA, 91766, USA; 8Institute of Psychology, Eotvos Loránd University, Budapest, 1053, Hungary; 9Department of Psychiatry, Wright State University Boonshoft School of Medicine and Dayton VA Medical Center, Dayton, OH, 45435, USA; 10Department of Psychiatry, University of Vermont, Burlington, VT, 05405, USA; 11Division of Nutrigenomics, The Kenneth Blum Behavioral & Neurogenetic Institute, Austin, TX, 78701, USA; 12Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel, IsraelCorrespondence: Saptadip Samanta; Debasis Bagchi, Email [email protected]; [email protected]; [email protected]: The human brain not only controls the various physiological functions but is also the prime regulator of circadian rhythms, rewards, and behaviors. Environmental factors, professional stress, and social disintegration are regarded as the initial causative factors of addiction behavior. Shift work, artificial light exposure at night, and chronic and acute jet lag influence circadian rhythm dysfunction. The result is impaired neurotransmitter release, dysfunction of neural circuits, endocrine disturbance, and metabolic disorder, leading to advancement in substance use disorder. There is a bidirectional relationship between chronodisruption and addiction behavior. Circadian rhythm dysfunction, neuroadaptation in the reward circuits, and alteration in clock gene expression in the mesolimbic areas influence substance use disorder (SUD), and chronotherapy has potential benefits in the treatment strategies. This review explores the relationship among the circadian rhythm dysfunction, reward circuit, and SUD. The impact of chronotherapy on SUD has also been discussed.Keywords: SCN, circadian rhythm dysfunction, melatonin, cortisol, drug addictio
Combined experimental and theoretical investigation of ligand and anion controlled complex formation with unprecedented structural features and photoluminescence properties of zinc(II) complexes
No full textBy using two potential tridentate ligands, HL1 [4-
chloro-2-[(2-morpholin-4-yl-ethylimino)-methyl]-phenol] and
HL2 [4-chloro-2-[(3-morpholin-4-yl-propylimino)-methyl]-phenol],
which differ by one methylene group in the alkyl chain,
four new ZnII complexes, namely, [Zn(L2H)2](ClO4)2 (1),
[Zn(L1)(H2O)2][Zn(L1)(SCN)2] (2), [Zn(L1)(dca)]n (3), and
[Zn2(L1)2(N3)2(H2O)2] (4) [where dca = dicyanamide anion]
were synthesized and structurally characterized. The results
indicate that the slight structural difference between the ligands,
HL1 and HL2, because of the one methylene group connecting
the nitrogen atoms provokes a chemical behavior completely
different from what was expected. Any attempt to isolate the
Zn(L2) complexes with thiocyanato, dicyanamido, and azide was unsuccessful, and perchlorate complex 1 was always obtained
ETAO Keyboard: Text Input Technique on Smartwatches
No full textAbstractIn the present day context of wearable computing, smartwatches augment our mobile experience even further by providing in- formation at our wrists. What they fail to do is to provide a comprehensive text entry solution for interacting with the various app notifications they display. In this paper we present ETAO keyboard, a full-fledged keyboard for smartwatches, where a user can input the most frequent English alphabets with a single tap. Other keys which include numbers and symbols are entered by a double tap. We conducted a user study that involved sitting and walking scenarios for our experiments and after a very short training session, we achieved an average words per minute (WPM) of 12.46 and 9.36 respectively. We expect that our proposed keyboard will be a viable option for text entry on smartwatches
Directional Area Based Minutiae Selection and Cryptographic Key Generation Using Biometric Fingerprint
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