22 research outputs found
Low Cost, High Performance and Efficiency Computational Photometer Design
No full textLow-cost, high-performance and efficiency computational photometer desig
Verification of Video Frame Latency Telemetry for UAV Systems Using A Secondary Optical Method
No full textYOUR EPOCH IS NOT FOR TRYING. IT’S FOR LIVING AND FOR DYING…
No full textThe article is devoted to biographies of three Russian physicians of the Silver Age (a period in the History of Russian culture between 1890 and 1917). They made early, significant and internationally recognized contribution into medical science and became eponymous, although social disasters of the twentieth century caused deep impact on their subsequent lives and careers, so their role was shadowed from global medical community. The article analyzes biographies and academic achievements of A-F.K. Siewert (aka: Zivert, Ziwert, von Siewert) (1872–1922), known for first description of the hereditary dyskinesia of cilia (as a triad of: situs inversus of the viscera, abnormal frontal sinuses producing sinusitis and bronchiectasis); S.S. Abramov (1875–1951), discoverer of primary idiopathic myocarditis, and N.I. Taratynov (1887–1919), who was the first in description of a local form of histiocytosis X (solitary eosinophilic granuloma) and predicted the eosinophilic origin of Charcot-Leyden crystals. The contribution of these scientists into Medicine is reviewed in context of historical epoch, on background of their different individual social choices and the fate of their families. Besides their eponymous descriptions, other medical priorities of these scholars are analyzed. Some previously unpublished materials from their family archives are presented, which witness for possible existence of unknown prototype for the main hero of ‘Doctor Zhivago’ novel by B. L. Pasternak and for probable priorities of doctor Zivert – in active diastole concept, or doctor Abramov – in description of dilated cardiomyopathy. The factors facilitating rapid development of theoretical and practical Medicine in imperial Russia of late XIX – early XX centuries are discussed. The conclusion of the author is that in any epoch, even the most cruel and unfavorable one, the creative activity is a way to social immortality (19 figs, 68 refs)
Prognostic significance of downregulated expression of the candidate tumour suppressor gene SASH1 in colon cancer.
No full textThe gene SASH1 (SAM- and SH3-domain containing 1) has originally been identified as a candidate tumour suppressor gene in breast cancer. SASH1 is a member of the SH3-domain containing expressed in lymphocytes (SLY1) gene family that encodes signal adapter proteins composed of several protein-protein interaction domains. The other members of this family are expressed mainly in haematopoietic cells, whereas SASH1 shows ubiquitous expression. We have used quantitative real-time PCR to investigate the expression of SASH1 in tissue samples from 113 patients with colon carcinoma, and compared the expression with 15 normal colon tissue samples. Moreover, nine benign adenomas and 10 liver metastases were analysed. Expression levels of SASH1 were strongly and significantly reduced in colon cancer of UICC stage II, III, and IV, as well as in liver metastases. Moreover, SASH1 was also found to be downregulated on protein levels by immunoblot analysis. However, SASH1 expression was not significantly deregulated in precancerous adenomas and in earlier stage lesions (UICC I). Overall, 48 out of 113 primary colon tumours showed SASH1 expression that was at least 10-fold lower than the levels found in normal colon tissue. Downregulation of SASH1 expression was correlated with the formation of metachronous distant metastasis, and multivariate analysis identified SASH1 downregulation as an independent negative prognostic parameter for patient survival. This study demonstrates for the first time that expression of a member of the SLY1-gene family has prognostic significance in human cancer
Image and Information Fusion Experiments with a Software-Defined Multi-Spectral Imaging System for Aviation and Marine Sensor Networks
No full textThe availability of Internet, line-of-sight and satellite identification and surveillance information as well as low-power, low-cost embedded systems-on-a-chip and a wide range of visible to long-wave infrared cameras prompted Embry Riddle Aeronautical University to collaborate with the University of Alaska Arctic Domain Awareness Center (ADAC) in summer 2016 to prototype a camera system we call the SDMSI (Software-Defined Multi-spectral Imager). The concept for the camera system from the start has been to build a sensor node that is drop-in-place for simple roof, marine, pole-mount, or buoy-mounts. After several years of component testing, the integrated SDMSI is now being tested, first on a roof-mount at Embry Riddle Prescott. The roof-mount testing demonstrates simple installation for the high spatial, temporal and spectral resolution SDMSI. The goal is to define and develop software and systems technology to complement satellite remote sensing and human monitoring of key resources such as drones, aircraft and marine vessels in and around airports, roadways, marine ports and other critical infrastructure. The SDMSI was installed at Embry Riddle Prescott in fall 2016 and continuous recording of long-wave infrared and visible images have been assessed manually and compared to salient object detection to automatically record only frames containing objects of interest (e.g. aircraft and drones). It is imagined that ultimately users of the SDMSI can pair with it via wireless to browse salient images. Further, both ADS-B (Automatic Dependent Surveillance-Broadcast) and S-AIS (Satellite Automatic Identification System) data are envisioned to be used by the SDMSI to form expectations for observing in future tests. This paper presents the preliminary results of several experiments and compares human review with smart image processing in terms of the receiver-operator characteristic. The system design and software are open architecture, such that other researchers are encouraged to construct and participate in sharing results and networking identical or improved versions of the SDMSI for safety, security and drop-in-place scientific image sensor networking
Correction: Comparison of RADAR, Passive Optical with Acoustic, and Fused Multi-Modal Active and Passive Sensing for UAS Traffic Management Compliance and Urban Air Mobility Safety
No full textComparison of RADAR, Passive Optical with Acoustic, and Fused Multi-Modal Active and Passive Sensing for UAS Traffic Management Compliance and Urban Air Mobility Safety
No full textBioética em discurso: efeitos sobre os processos de constituição do sujeito enfermeira/o na terapia intensiva
No full textTese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-graduação em EnfermagemInvestigação qualitativa, balizada na analítica foucaultiana com aproximações ao referencial pós-estruturalista, tendo como objetivos: analisar a constituição histórica do discurso da bioética em sua articulação com o discurso da tecnobiomedicina e o modo como os desdobramentos estratégicos e tecnológicos deste discurso atravessam o processo de produção do sujeito enfermeiro/a gerando determinados modos de conceber e intervir deste sujeito no contexto da terapia intensiva; conhecer as tensões no fazer/saber enfermagem que podem ser discursivamente articuladas à bioética, ou problematizadas a partir da emergência deste discurso. A tese utilizou fontes documentais e de entrevistas com enfermeiros/as intensivistas e teve sua proposição aprovada por Comitê de Ética (Parecer n° 186/07/CEP/UFSC). O corpus documental foi composto por 113 artigos publicados no período de 1984-2007, nos periódicos nacionais de enfermagem: Revista Latino-Americana de Enfermagem, Revista Acta Paulista, Revista Texto & Contexto Enfermagem, Revista Escola de Enfermagem USP), Revista Brasileira de Enfermagem, além da Revista o Mundo da Saúde (multidisciplinar). A busca foi orientada pelos descritores bioética e UTI e enfermagem, ética e UTI, bioética e enfermagem e ampliada para artigos com temas relacionais com a bio/ética. Foram entrevistados/as 20 (vinte) enfermeiros/as inseridos/as no contexto da terapia intensiva, utilizando-se o critério de saturação de dados. Com baliza ao corpus de análise, foram exploradas as temáticas das iatrogenias, autonomia e responsabilidade no cuidar. Na temática iatrogenias, ativou-se uma reflexão sobre o agir do/a enfermeiro/a em um contexto permeado pela possibilidade sempre latente de falhar tanto no procedimento como na conduta; e do encontro deste profissional com a obrigação de corrigir esta falha, não tanto ou não apenas no conhecimento ou na lei, mas na prática de si mesmo. O tema da autonomia foi analisado a partir do conceito de cuidado de si, desdobrando-se em categorias que expressaram o privilegiamento da moral como obediência à Lei; da conduta e da moral sobre o conhecimento técnico; e da governabilidade de si no confronto com a técnica. Estas se configuraram como possibilidades éticas do sujeito enfermeira/o intensivista, não como etapas seqüenciais ou concorrentes, mas coligadas e confluentes na experiência atual. A questão da responsabilidade do cuidar desdobrou-se em categorias que expressaram a responsabilidade frente às novas linguagens e a enfermagem como guardiã de certos atributos da UTI. Autonomia e responsabilidade no cuidar, de um lado, evidenciaram algumas possibilidades éticas do sujeito enfermeira/o, constituídas e desfeitas estrategicamente na contingência histórica; de outro lado, permitiram mapear um dos desdobramentos estratégicos e tecnológicos do discurso da bio/ética, gerando modos de conceber e intervir do sujeito enfermeiro/a na UTI. Uma autonomia como prática de si; uma responsabilidade do cuidar que evidencia uma #sutileza# na obrigação do dever ser, em um tempo de viver a enfermagem, também, como perita, conselheira, autoridade patente. Ao contrário de um apagamento da relação paradoxal entre a responsabilidade e a autonomia dos/as enfermeiros/as, sinalizou-se as múltiplas possibilidades de combinações de graus de autonomia e de responsabilidade, nem sempre ideais ou caminhando no mesmo sentido. This qualitative investigation, landmarked in Foucaltian analysis with approximationg to post-structuralist theory, explores iatrogenias as one of the tensions of nursing performance/knowledge which can be discursively articulated to bioethics and to techno biomedicine. Documental sources and interviews with intensive care nurses permitted an activation of reflection upon a nurse#s actions in a context permeated by the always latent possibility of failing, in both procedure and conduct. Based on such possibility, intensive care nurses find themselves obligated to correct their failure, not as much or merely in knowledge, nor law, but in self practice
Eponymous and no longer anonymous: hard life and long fame of Russian physicians. Proceeding II: Who was Doctor Taratynov?
No full textThe article is devoted to biographies of Russian physicians of the Silver Age (a period in the History of
Russian culture between 1890 and 1917). They made early, significant and internationally recognized
contributions to medical science and became eponymous, although social disasters of the twentieth
century caused deep impact on their subsequent lives and careers so that their role was occluded
from the global medical community. These proceedings are devoted to the biography and academic
achievements of Nikolay Ivanovich Taratynov (1887–1919), known for first description of a local form
of histiocytosis X (solitary eosinophilic granuloma). It was also he who first correctly hypothesized
that Charcot-Leyden crystals belong to products of eosinophilic leucocytes. He also studied the role of
the immune system in the regeneration of muscles, but he was killed during Civil War in Russia. The
previous proceeding dealt with academic and personal biography of A. K. Zivert, known for first description
of Siewert-Kartagener triad, and the subsequent proceeding will cover also biography of their
contemporary S. S. Abramov, discoverer of primary idiopathic myocarditis. The contribution of these
scientists to Medicine is reviewed in the context of historical epoch against the background of their
different individual social choices and the fate of their families. Besides their eponymous descriptions,
other medical innovations of these scholars are analyzed. Some previously unpublished materials from
their family archives are presented, which witness to the possible existence of an unknown prototype
for the main hero of the novel ‘Doctor Zhivago’ by B. L. Pasternak and for probable other priorities. The
factors facilitating rapid development of theoretical and practical Medicine in the imperial Russia of
the late 19th and early 20th centuries are discussed. One of them was definitely the fruitful activity of
the Imperial Kazan University, which was at the top of its academic development during that period.
The conclusion of the author is that in any epoch, even the most cruel and unfavorable one, creative
activity is a means toward social immortality. Refs 19. Figs 12
Software Defined Multi-Spectral Imaging for Arctic Sensor Networks
No full textAvailability of off-the-shelf infrared sensors combined with high definition visible cameras has made possible the construction of a Software Defined Multi-Spectral Imager (SDMSI) combining long-wave, near-infrared and visible imaging. The SDMSI requires a real-time embedded processor to fuse images and to create real-time depth maps for opportunistic uplink in sensor networks. Researchers at Embry Riddle Aeronautical University working with University of Alaska Anchorage at the Arctic Domain Awareness Center and the University of Colorado Boulder have built several versions of a low-cost drop-in-place SDMSI to test alternatives for power efficient image fusion. The SDMSI is intended for use in field applications including marine security, search and rescue operations and environmental surveys in the Arctic region. Based on Arctic marine sensor network mission goals, the team has designed the SDMSI to include features to rank images based on saliency and to provide on camera fusion and depth mapping. A major challenge has been the design of the camera computing system to operate within a 10 to 20 Watt power budget. This paper presents a power analysis of three options: 1) multi-core, 2) field programmable gate array with multi-core, and 3) graphics processing units with multi-core. For each test, power consumed for common fusion workloads has been measured at a range of frame rates and resolutions. Detailed analyses from our power efficiency comparison for workloads specific to stereo depth mapping and sensor fusion are summarized. Preliminary mission feasibility results from testing with off-the-shelf long-wave infrared and visible cameras in Alaska and Arizona are also summarized to demonstrate the value of the SDMSI for applications such as ice tracking, ocean color, soil moisture, animal and marine vessel detection and tracking. The goal is to select the most power efficient solution for the SDMSI for use on UAVs (Unoccupied Aerial Vehicles) and other drop-in-place installations in the Arctic. The prototype selected will be field tested in Alaska in the summer of 2016
