1,042 research outputs found
Polymeric micelles and the Dy-166/Ho-166 generator: A study of the loading mechanism of Dy/Dy-166 and Ho-166 into PCL-b-PEO polymeric micelles for imaging and cancer treatment
No full textA radioisotope used in radionuclide therapy is Holmium-166 (Ho-166). The treatment effectiveness of Ho-166 could be improved by the use of a so called in vivo Dysprosium-166(Dy-166)/Ho-166 generator. The application of this generator is hindered by an effect called internal conversion (IC). This affect can arise after the decay of Dy-166 to Ho-166, which can cause separation of Ho-166 from its carrier.Polymeric micelles might form a solution in the application of the Dy-166/Ho-166 generator in radionuclide therapy. The main goal of this thesis was to investigate and understand the loading mechanism of metallic species and polymeric micelles with a focus on the loading of Dy/Dy-166 and Ho-166. It was found that it was not effective to load metallic species (Dy/Dy-166) as free ions or as solid precipitates. Loading metallic species as aqueous hydroxides showed to be crucial for achieving a good loading and high stability. The second goal was to study if polymeric micelles were able to retain Ho-166 inside their core under the effects of internal conversion. No additional losses of Ho-166 were found when Dy/Dy-166 and Ho-166 were loaded into the micelles. It was concluded that the PCL-PEO micelles prevented the loss of Ho-166 under internal conversion effects.Applied Science
Electrical and Optical Study of Dy doped Bismuth Layer SrBi2Ta2O9(SBT)
No full textThe two layer Aurivillius compound SrBi2Ta2O9 (SBT) and SrBi2-xDyxTa2O9 (x=0.025, 0.05, 0.1) was synthesized by using a solid state sintering method. The X-ray diffraction (XRD) analysis revealed that the dysprosium substituted ceramic SrBi2Ta2O9 have a pure two-layer Aurivillius type structure. The effects of Dysprosium oxide on the microstructure, ferroelectric, dielectric and optical properties of the ceramics were investigated. Dy doping is found to be significantly affect on the structural and physical properties of SBT. The dielectric constant (Ԑ) and transition temperature (Tc) of Dy-doped samples was found to be decrease with increase of Dy content. Well-developed P (polarization)-E (Electric field) hysteresis loops were observed for all the samples and also the band-gap (Eg) of this sample was verify by UV-VIS spectrophotometer
Rare earth Dy activated Li3PO4:Dy phosphors for lyoluminescence dosimetry of ionizing radiations
No full text Rare earth Dy doped Li3PO4 phosphate based phosphors were prepared by high temperature solid state diffusion technique. The peak LL intensity initially increases with increasing mass of the sample, then tends to attain a saturation value for higher mass of the solute added to the solvent. Eaelier experiments on gamma irradiated crystals have proved that the light emission originates from the recombination of released F-centres with trapped holes (V2-centres) at the liquid-solid interface.In this paper lyoluminescence(LL) characteristics of Li3PO4:Dy phosphors have been reported . These LL characteristics of Li3PO4 phosphor may be useful for high radiation dosimetry using LL technique
beta-delayed proton decays and spin assignments for Tb-140, Dy-141 and Dy-143
No full textThe proton-rich isotopes Tb-140 and Dy-141 were produced via the fusion evaporation reaction Ca-40+ Cd-106. Their beta-delayed proton decays were studied by p-gamma coincidence in combination with a He-jet tape transport system, and half-lives, proton energy spectra, gamma-transitions following the proton emission, as well as beta-delayed proton branching ratios to the low-lying states in the grand-daughter nuclei were determined. Comparing the experimental data with statistical model calculations, the ground-state spins of Tb-140 and Dy-141 were found to be consistent with 7 and 9/2, respectively. The configuration-constrained nuclear potential energy surfaces (NPES) of Tb-140 and Dy-141 were calculated using the Woods-Saxon-Strutinsky method, which suggest the ground-state spins and parities of Tb-140 and Dy-141 to be 7(+) and 9/2(-), respectively. In addition, the configuration-constrained NPES of Dy-143 were calculated, which predict a 1/2(+) ground state and a 11/2(-) isomer with excitation energy of 198 keV. These findings are consistent with our previous experimental data on Dy-143 reported in Eur. Phys. J. A 16, 347 (2003).Physics, NuclearPhysics, Particles & FieldsSCI(E)3ARTICLE137-402
Solvent Extraction and Separation of Nd, Pr and Dy from Leach Liquor of Waste NdFeB Magnet Using the Nitrate Form of Mextral® 336At in the Presence of Aquo-Complexing Agent EDTA
No full textSolvent extraction and separation of Pr, Nd and Dy from a synthetic leach solution of spent NdFeB magnet from wind turbines in the presence of aquo-complexing agent Ethylenediaminetetraacetic acid (EDTA) was studied using the nitrate form of Mextral® 336At ([336At][NO3]) as an extractant. The effect of different process parameters such as pH, extractant, nitrate, and EDTA concentrations on the extraction of Pr, Nd and Dy was studied. The extraction of these rare earths elements follows the order Pr > Nd > Dy, whereas EDTA forms stable complexes in the order Dy > Nd > Pr. The synergy of these two effects improved the selectivity among these elements as compared to when no aquo-complexing agent was used. The mechanism of extraction of rare earth elements was established by slope analysis method. The Fourier-Transform Infrared Spectroscopy (FTIR) spectra of [336At][NO3] and extracted Nd complex were recorded to understand the interaction of extractant with rare earth metal ions in the organic phase
Radiation Hardness of Undoped BGO Crystals
No full textWe measured the radiation hardness of undoped BGO crystals from two different manufacturers. Such crystals are proposed to be used in a small angle calorimeter of the BELLE detector of the KEK B-factory. Transparency and scintillation light output of the crystals were monitored to see the effect of radiation damage. The crystals show considerable radiation hardness up to 10.2 MRad equivalent dose, which is much higher than the maximum expected dosage of 500 kRad per year of running at BELLE. Submitted to NIM-A. y Corresponding author; Present address : University of Hawaii, Honolulu, HI 96822, U.S.A.; [email protected] 1 Introduction Bismuth Germanate (Bi 4 Ge 3 O 12 ) crystals, commonly known as BGO, have been extensively used for electromagnetic calorimetry in high energy physics experiments[1]. Advantages of BGO are its excellent e=fl energy resolution (0.3 -- 1 %/ q (E(GeV )), high density, short radiation length, large refractive index, suitable scintillating properties(f..
Direct numerical simulation of turbulent Couette-Poiseuille flow with zero skin friction
No full textThe near-wall scaling of mean velocity U(y) is addressed for the case of zero skin friction on one wall of a fully turbulent channel flow. The present DNS results can be added to the evidence in support of the conjecture that U is proportional to √yw in the region just above the wall at which the mean shear dU/dy = 0
Iron oxide nanoparticles as carriers for the Dy-166/Ho-166 in vivo generator: A study into the characteristics and retention of Dy and Ho in iron oxide nanoparticles
No full textBackground:Cancer is one of the leading causes of death worldwide. Targeted radionuclide therapy has become a important treatment, this is when a carrier molecule is attached to a radionuclide to deliver cytotoxic radiation levels to diseased cells. β− emitters are frequently used in RNT because they have a long penetration depth, such as the dysprosium-166/holmium-166 (166Dy/166Ho) in vivo generator. The 166Dy/166Ho in vivo generator shows great potential for large tumors because of the long half-life time of the mother nuclide 166Dy and the emission of high energy β− from the daughter nuclide 166Ho. Previous research shows the release of 72 % of the 166Ho when 166Ho is bound to conventional chelators due to internal conversion after the β− decay. The aim of this thesis is to synthesize an iron oxide nanoparticle as carrier for the 166Dy/166Ho in vivo generator. This iron oxide nanoparticles (SPIONs) should prevent internal conversion and thus the loss of the daughter nuclide 166Ho.Results:The dysprosium doped iron oxide nanoparticles were synthesized successfully with an average diameter of 6.1 ± 1.5 nm, measured with TEM. The DLS and TEM results showed that the SPIONs were aggregating. The labeling efficiency represents how much Dy is retained in the Dy doped SPIONs, for the non-radioactive Dy this was measured with the ICP/OES. The labelling efficiency was 3.21 ± 0.8 %. The 166Dy doped iron oxide nanoparticles were also synthesized successfully with a radiolabelling efficiency of 3.12 ± 2.2 %, measured with a 2480 Wizard 2 Gamma counter. The retention of 166Dy + 166Ho was 79.2 ± 1.8 % after 96 h.Conclusion:The retention of 166Dy + 166Ho in iron oxide nanoparticles was 79.2±1.8 % after 96 hours. This is much higher than the retention of 28% by conventional chelators. This means that the iron oxide nanoparticls is a safer carrier for the 166Dy/166Ho in vivo generator than the conventional chelator.Applied Physic
Carrier recombination processes and divalent lanthanide spectroscopy in YPO4:Ce3+;L3+ (L=Sm,Dy,Tm)
No full textWe studied charge carrier trapping, detrapping, and recombination phenomena in Ce3+ doped YPO4, codoped with Sm3+, Dy3+, or Tm3+. Ce ions trap the holes and Sm, Dy, and Tm trap electrons created during x-ray irradiation. By means of red to infrared stimulation, the trapped electrons can be back transferred to Ce leading to shorter wavelength Ce3+?5d-4f luminescence. Excitation spectra for this recombination luminescence were recorded from 10 K to room temperature. It provides information on the excited state energies of divalent Sm, Dy, and Tm with respect to the lanthanide ground state energy and with respect to the mobility edge energy of YPO4. From the temperature dependence, insight is obtained on the carrier recombination pathways. We will identify temperature independent tunneling recombination, recombination by thermal excitation to the conduction band, and phonon-assisted delocalization of electrons from impurity states within the conduction band.QN/Quantum NanoscienceApplied Science
Study on Superdeformed Bands of Dy-152 and Its Neighboring Nuclei
No full textDy-152 is the first observed superdeformed nucleus, whose band structure reflects the typical distribution of high j low Omega orbitals of superdeformed nuclei in A similar to 150 mass region. The particle-number conserving treatment of the cranked shell model with monopole and quadrupole paring interactions is adopted to investigate the observed six superdeformed bands in Dy-152. The pi[523]7/2 orbital is emphasized for the first time to interpret the microscopic structure of band 2 and 3 of Dy-152. A new comprehension is proposed on the basis of ever existing experimental and theoretical results, and the reliability is illustrated by several superdeformed bands of neighboring nuclei.Physics, Fluids & PlasmasSCI(E)EI中国科学引文数据库(CSCD)05408-4111
- …
